手性拆分

β-受体阻滞剂类药物的RP-HPLC手性拆分

Chiral Separation of β - Blocking Agents by RP-HPLC

众多手性拆分方法中，毛细管电泳（CE）技术因其分析速度快、分离能力强、试剂消耗少等优点而被广大研究者广泛应用。

Among so many chiral separation methods , capillary electrophoresis ( CE ) was applied to chiral separation by many researchers because of its short analysis time , high resolving power and less reagent consumption .

考察了不同手性拆分试剂对手性选择性的影响，其中羧甲基β环糊精（CMβCD）能够给出满意的拆分结果。

Several cyclodextrins ( CDs ) were applied as the chiral selectors and it was found that the ionic modified carboxymethyl β cyclodextrin ( CM β CD ) could give satisfactory enantioselectivity .

目的比较在毛细管电泳中不同中性环糊精（CD）及其衍生物对氧氟沙星对映体的手性拆分能力，并提出可能的手性识别机制。

AIM : To compare the separation ability of different neutral cyclodextrins ( CD ) and their derivatives on ofloxacin enantiomer by capillary electrophoresis ( CE ) and to explore the possible mechanisms of chiral separation .

阐述了酒石酸衍生物手性拆分对映体的多种机理，并对酒石酸衍生物在对映体的HPLC手性拆分中的应用前景做了展望。

Several kinds of chiral recognition mechanism of tartaric acid derivatives as chiral selectors are discussed and the development trends of tartaric acid derivatives as chiral selectors in the separation of enantiomers in HPLC are prospected .

μ3-S盖帽的外消旋金属簇合物的直接手性拆分

Direct Chiral Separation of (μ _3-S ) - Bridged Racemic Metal Clusters

在对手性农药中间体的分离中，H1-CD表现出了良好的手性拆分能力。

We study enantioseparation of some chiral insecticide 's intermediates on H1-CD .

毛细管电泳手性拆分N-Fmoc保护氨基酸

Chiral Separation of N-Fmoc Amino Acids by Capillary Electrophoresis

功能化AAILs的高分离能力使得其在制备规模的手性拆分中优势明显。

As chiral separation media , the high separation capacities of ionic liquids have obvious advantages for chiral extraction in preparative scale . 3 .

支配手性拆分的主要因素是外消旋萘普生酯在CTA手性空腔中的体积大小适应性，尤其是立体结构的空间适应性是关键。

The decisive factor for the chiral recognition is the fitness of the size of racemic naproxen ester to the chiral cavities of CTA , however the space fitness of the steric structure of the solute is also a key point .

通过对反应原料的摩尔配比、反应温度、溶剂量以及手性拆分等条件的优化，并在最后产品成盐时用干燥HCl气体取代液体盐酸，使最后产品总收率达到18.4%，高于文献报道的13%。

The dry HC1 , instead of concentrated HC1 solution , was used in the final salt-formation reaction . The overall recovery of hydrochloride Duloxetine reached 18.4 % , which is higher than that with original process reported in the literature ( 13 % ) .

通过电渗析过程拆分DL-对羟基苯甘氨酸（DL-4-hydroxyphenylglycine，DL-HPG）外消旋混合物以评价该膜的手性拆分效果。

Electrodialysis process for the separation of DL-4-hydroxyphenylglycine racemic mixture was carried out to evaluate these chiral selective cation-exchange membranes .

选择性扩散和选择性吸附手性拆分膜及其应用

Selective-Diffusion or Selective-Sorption Membranes and their Application Prospect in Chiral Resolution

液相色谱手性拆分机理的热力学方法研究

Thermodynamic Study on the Mechanistic Aspects of Chiral Resolution by HPLC

胺修饰β-环糊精在手性拆分中的应用

Application of Amine - modified β - Cyclodextrins in Chiral Resolution

本论文研究的目的就是为实验室制备2`-氯苯乙酮及它的衍生物，作为进行手性拆分研究的底物。

The aim of this work is to prepare 2-chloroacetophenone derivatives .

手性拆分技术及其在手性药物合成中的应用新进展

Application progress of novel optical resolution technologies in the chiral drugs

外消旋苯丙氨酸及其衍生物的合成与手性拆分

The Synthesis and Chiral Resolution of DL-phenylalanine and Its Derivatives

毛细管电泳手性拆分中的二元环糊精体系

Chiral Drug Separation in Binary Cyclodextrin Systems by Capillary Electrophoresis

高效液相色谱法对反式-1,2-二取代环丙烷类化合物的手性拆分

Enantiomeric Resolution of trans 1,2 Disubstituted Cyclopropane by High Performance Liquid Chromatography

无胶筛分毛细管电泳相互作用分析及毛细管电泳手性拆分

Non Gel Capillary Electrophoresis Interaction Analysis and Chiral Separation of Capillary Electrophoresis

毛细管电泳手性拆分喹诺酮类药物对映体

Chiral Separation of Enantiomers of Quinolone Drugs by Capillary Electrophoresis

毛细管电泳技术在手性拆分中的最新进展和应用研究

Chiral Separation by Capillary Electrophoresis : Recent Developments and Applications

山莨菪碱和阿托品毛细管电泳手性拆分研究

Study on the Enantiomeric Separation of Anisodamine and Atropine by Capillary Electrophoresis

人血清白蛋白柱上药物的手性拆分

Enantiomeric Separation of Drug on Human Serum Albumin Column

环糊精接枝聚硅氧烷气相色谱固定相的手性拆分性能

Chiral Resolution of β - Cyclodextrin Bonded Polysiloxane as Gas Chromatographic Stationary Phase

醋酸纤维素液相色谱固定相的制备与手性拆分

Preparation of Cellulose Triacetate Stationary Phase and Separation of Chiral Compounds by HPLC

维拉帕米和布比卡因的毛细管电泳手性拆分

Chiral Separation of Verapamil and Bupivacaine by Capillary Electrophoresis

杀鼠灵对映体的高效毛细管电泳手性拆分

Enantiomeric Separation of Dethmor by High Performance Capillary Electrophoresis

盐酸苯海索的高效毛细管电泳手性拆分

Enantiomeric Separation of Benzhexol Hydrochloride by Capillary Zone Electrophoresis