抗血小板抗体

用单克隆抗体对ITP自身抗血小板抗体及其相关抗原的初步研究

A preliminary study on antiplatelet autoantibodies and their related antigens with monoclonal antibodies in ITP

结论：FCM可成为血小板自身抗体检测的一项新的快速简便的方法，与ELISA等方法同时应用可进一步提高ITP患者抗血小板抗体检测的阳性率与可靠性。

Conclusion : FCM can be used as a new , rapid and simple method in detecting platelet autoantibody . FCM , in combination with ELISA , would improve the reliability and the positive percentage of PAIgG measurement in ITP patients .

目的：为深入研究抗血小板糖蛋白抗体基因的表达提供途径。

Objective : To further investigate the expression of the gene of anti-platelet antibody .

以广泛皮肤、粘膜或内脏出血，血小板减少，骨髓巨核细胞发育、成熟障碍，血小板生存时间缩短及抗血小板自身抗体出现为特征。

It is characterized with extensive skin , mucosa or internal organs hemorrhage , the decrease of platelet count , failure of megakaryocyte development and maturity in bone marrow , platelet survival time shortening and appearence of platelet-associated autoantibody .

应用抗血小板膜糖蛋白抗体、免疫组织化学技术、对10例骨髓增生异常综合征（MDS）骨髓活检组织中巨核细胞（MK）进行了观察。

N immunohistochemical study was performed on trephine biopsy specimens of bone marrow in 10 patients with myelodysplastic syndromes ( MDS ) .

目的比较抗血小板特异性抗体、PAIgG及淋巴细胞亚群在特发性血小板减少性紫癜（ITP）及非免疫性血小板减少症中的水平，以评价其在ITP中的诊断价值。

Objective To compare specific autoantibodies against platelet glycoprotein ( GP ), platelet-associated IgG ( PAIgG ) and lymphocyte subpopulations in the patients with idiopathic thrombocytopenic purpura ( ITP ) and non-immune thrombocytopenia .

目的检测恶性肿瘤非免疫性血小板减少患者的抗血小板特异性抗体，评价单克隆抗体特异性俘获血小板抗原（MAIPA）诊断及鉴别诊断价值。

Objective To study the possibility of the exist of specific antibody against platelet in tumor patients and to evaluate the value of MAIPA in measure of specific antibody against platelet in malignant tumor patients with nonimmune thrombocytopenic purpura .

抗血小板糖蛋白VI单克隆抗体的制备及其功能研究

Preparation and characterization of a monoclonal antibody directed against platelet glycoprotein VI

抗血小板糖蛋白IIb/IIIaFab抗体的原核表达及其生物活性

Expression of antibody Fab against platelet IIb / IIIa in E.coli and characterization of its biological activity

目的：探讨小剂量方案美罗华治疗ITP的疗效、安全性及治疗前后B淋巴细胞、抗血小板膜白IgG抗体的变化。

Objective : To evaluate the efficacy and safety as well as the effects of lower dose of rituximab on B-lymphocytes and anti-platelet glycoprotein-specific antibodies in patients with immune thrombocytopenic purpura ( ITP ) .

本文应用三种抗血小板膜糖蛋白单克隆抗体，按ELISA间接法、ELISA双抗体夹心法、ELISA竞争法，对ITP患者自身抗血小板抗体及其相关抗原进行了初步研究。

We studied on antiplatelet autoantibodies and their related antigens in patients with ITP , by using three McAb against platelet glycoproteins , ( anti-GPIb , IIb , IIIa ), according to ELISA indirect method , ELISA sandwich method and ELISA competitive method .

抗血小板人源化抗体的研究进展

Advances in the Studies of Humanized Anti-platelet Antibody & Review

抗血小板膜糖蛋白单克隆抗体洗脱性血管内支架体外实验研究

In Vitro Study of Platelet Glycoprotein Monoclonal Antibody Eluting Stents

本文就血小板在出血和血栓性疾病中的作用，人源化抗体的发展现状和抗血小板人源化抗体在出血性及血栓性疾病中的应用作一综述。

The important role of platelet in bleeding and thrombotic diseases , the present status of development on study of humanized anti-platelet antibody and its application in treatment of bleeding and thrombotic diseases were summarized in this review .