神经变性

星形胶质细胞在炎症相关的神经变性疾病发病机制中的作用研究

Role of Astrocyte in the Aetiology of Neurodegeneration Diseases Involving Inflammation

神经变性过程中钙稳态变化与氧化应激初步研究

The Relationship of Calcium Homeostasis and Oxidative Stress in Neurodegeneration

阿尔茨海姆病（Alzheimer'SDisease，AD）是一种神经变性性疾病。

Alzheimer 's disease is a kind of neural degenerative disease .

NA干扰及其在神经变性性疾病研究中的应用

RNA interference and its application to neurodegenerative diseases

帕金森病（PD）是锥体外系统的进行性神经变性疾病，其发病机制有多种学说。

Parkinson Disease ( PD ) is a kind of progressive neural degeneration of nigrostriatal system .

帕金森病（PD）又名震颤麻痹，是一种常见的进行性神经变性疾病。

Parkinson 's disease ( PD ), namely paralysis agitans , is a vulgar nervous system disease .

帕金森病（PD）是主要发生在中老年人锥体外系统的进行性神经变性疾病。

Parkinson 's disease ( PD ) is a neurodegenerative disease which mostly occurs in the extrapyramidal system of middle or old age .

α-synuclein片段NAC对多巴胺能神经元的神经变性作用

Neurodegenerative Effect of α - Synuclein Fragment-NAC on Dopaminergic Neurons

肌萎缩侧索硬化（AmyotrophicLateralSclerosisALS）是一个致命的神经变性疾病。

Amyotrophic lateral sclerosis ( ALS ) is a common progressive neurodegenerative disease in central nervous system .

神经变性疾病Batten病中的谷氨酸脱羧酶的自身免疫

Autoimmunity to glutamic acid decarboxylase in the neurodegenerative disorder Batten disease

18F-FDGPET在神经变性性痴呆的诊断与鉴别诊断中具有重要的价值，SPM分析是可靠有效的图像分析工具。

FDG PET is a valuable means to diagnose and differentiate neurodegeneration dementia , and SPM is a reliable and useful method .

帕金森病（Parkinson'SDisease，PD）是一中老年人常见的慢性进行性神经变性疾病，主要临床表现为震颤、运动减少、肌强直和姿势障碍等。

Parkinson 's disease ( PD ) is a chronic progressive neurodegenerative disorder among middle age and old-age persons . PD 's cardinal manifestations are tremor , rigidity , bradykinesia and postural instability et al .

随着年龄的增长，EPO在CNS的含量逐渐减少，提示EPO可能和衰老有关的神经变性病有关。

In addition , with advancing age , EPO levels gradually reduced in CNS , suggesting that EPO may be related to aging-related neurodegenerative disease .

神经变性疾病细胞膜损伤机制：分泌型磷脂酶A2-Ⅴ亚型诱导小鼠皮质及海马神经元前列腺素E2受体表达的研究

Mechanisms of plasmalemma injury of neurodegenerative disease : the expression of prostaglandin E2 receptor in cortical and hippocampal neurons of mice induced by secretory phospholipase A_2 - ⅴ

HgCl2染毒大鼠的胫神经变性

Degeneration of Tibial Nerve Induced by HgCl_2 in Rats

RoyFreeman教授：基于临床前研究的数据和最近的临床资料，有许多生化途径在神经变性的功能障碍中发挥着关键作用。

Prof Roy Freeman : There are a number of biochemical pathways based on preclinical data and more recently clinical data which play a key role in dysfunction of nerve degeneration .

αsynuclein可能起到联系基因和环境因素在PD中的发病机制的作用，而多巴胺导致的氧化应激则可能是神经变性的共同途径。

α - synuclein may contribute to the relationship between genetic and environmental factors in pathogenesis of Parkinson disease . And oxidative stress generated by dopamine may be the common pathway of the neurodegenerative .

ICAM-5通过ERM/PI3K/Akt信号途径减轻Aβ诱导的神经变性

ICAM-5 Attenuates Amyloid Beta Protein Induced Neuronal Degeneration by ERM / PI3K / Akt Pathway

研究发现，JNK信号转导通路与多种疾病（包括肥胖、2型糖尿病、炎症、神经变性以及肿瘤等）的发生机制有关[3]。

Studies have shown that JNK signaling pathway is relevant to the pathogenesis of many diseases ( including obesity , type 2 diabetes , inflammation , nerve degeneration , and tumors , etc. ) .

近年来研究发现，糖尿病时视网膜发生微血管病变之前就出现了视网膜Müller细胞功能的改变，包括谷氨酸代谢异常、胶质细胞反应性增加、Müller细胞凋亡等，这些改变统称视网膜神经变性。

More recently , it has emerged that M ü ller cells ′ dysfunctions occur in those with diabetic retinopathy , including altered glutamate metabolism , glial cell reactivity , increased apoptosis and so on .

选择12只形成感觉神经变性盐敏感高血压wistar大鼠及10只对照同龄wistar大鼠，麻醉下取外周动脉组织，用PCRELISA方法测定高血压及对照大鼠动脉组织端粒酶活性。

Select 12 Wistar rats in with salt-sensitive hypertension , and 10 normal Wistar rats as control , with age and gender being comparable between two groups . Arterial tissues were harvested under anesthesia , and telomerase activities of arterial tissues in both groups were measured with PCR-ELISA .

在体和离体实验也提示GDNF和BONF可能对PD或其他神经变性疾病有治疗作用，但GDNF等大分子蛋白不能通过血脑屏障，使其难以应用于临床。

Data in vitro and in vivo suggests that GDNF and BDNF could be a useful therapy for PD and other neurodegenerative disorders , but these neurotrophic factors can 't penetrate BBB ( barrier ), which limits the usage of neurotrophic factors in clinic .

神经变性与肌肉内吞摄取增加的关系

Relationship Between Nervous Degeneration and Increase of Endocytic Uptake in Muscle

氧化损伤在神经变性疾病中发挥着重要的作用。

Oxidative damage plays a critical role in many neurodegenerative diseases .

脊髓；神经变性；磁共振成像；诊断。

Spinal cord ; Nerve degeneration ; Magnetic resonance imaging ; Diagnosis .

组蛋白脱乙酰基酶6在聚集小体和神经变性疾病中的作用

Role of histone deacetylase 6 in aggresome and neurodegenerative diseases

神经变性疾病是我们老龄化社会最大挑战之一。

Neurodegenerative diseases represent one of the greatest challenges of our aging society .

帕金森病相关神经变性中自噬溶酶体途径的作用。

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson 's disease .

胼胝体、锥体束和周围神经变性一家系报告

Hereditary pyramidal tract , corpus callosum and peripheral degeneration , one family report

生长因子与糖尿病性神经变性及再生

Growth factor in diabetic neuropathy and nerve regeneration