缺血再灌注
- 网络ischemia-reperfusion;I-R;hIR
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在脑缺血再灌注过程中,产生氧自由基等毒性产物攻击DNA和DNA损伤修复系统,两者共同参与脑缺血再灌注损伤的病理过程,保护DNA通常可以减轻脑缺血再灌注损伤。
During cerebral ischemia-reperfusion , harmful products , especially oxygen free radicals , attacked DNA and DNA repairing system , which influenced cerebral ischemia-reperfusion injury .
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目的观察异丙酚对大鼠胃缺血再灌注损伤(gastricischemia-ReperfusionInjury,GI-RI)的影响。
Objective To investigate the effect of propofol on gastric ischemia-reperfusion injury ( GI-RI ) .
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甲基维生素B(12)对反复前脑缺血再灌注大鼠学习、记忆功能的影响
The Effects of Methyl-vitaminB_ ( 12 ) on Leaning and Memory Following Repeated Forebrain Ischemia-reperfusion in Rats
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17一p一雌二醇可减轻大鼠肝脏缺血再灌注后肝组织损伤,加快肝脏缺血再灌注损伤后肝脏功能的恢复。
( 2 ) 17-beta-estradiol significantly protects liver from ischemia reperfusion injury and accelerate comeback of liver function after liver ischemia reperfusion injury .
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目的探讨胸段硬膜外阻滞(TEA)对缺血再灌注损伤心肌的保护作用。
Objective : To explore the protective effects of thoracic epidural anesthesia ( TEA ) aganist myocardial ischemia-reperfusion injury .
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异氟烷预处理对缺血再灌注损伤鼠脑组织中Bcl-2和Bax的mRNA表达的影响
Effect of isoflurane preconditioning on Bcl-2 and Bax mRNA expression after ischemia / reperfusion in gerbil brain
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IL-1β和IL-6在脑缺血再灌注微血管内皮细胞炎症反应中的作用
The role of IL-1 β and IL-6 in inflammation of endothelial cell after global cerebral ischemia-reperfusion
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结论BDNF比NGF分布广泛,缺血再灌注早期额叶有NGF、BDNF较好的神经元保护机制;
Conclusion The distribution of BDNF was wider than that of NGF .
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MT可通过阻止线粒体凋亡途径而保护模拟缺血再灌注诱导小脑颗粒细胞的凋亡。
MT can suppress the apoptosis of cerebellar granule cells by preventing the mitochondrial apoptosis pathway .
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结果缺血再灌注组脑组织SOD下降,血清SOD先升后降;
Results For focal cerebral ischemia group , concentration of brain tissue SOD decreased and serum SOD increased and then decreased .
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大鼠小肠缺血再灌注后肝Bax,Bcl-2,p53的表达和超微结构改变
Expression of Bax , Bcl-2 , p53 and ultrastructural change in the liver after small intestine ischemia-reperfusion in rats
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慢性脑低灌注状态缺血再灌注后大鼠海马P21和P53蛋白的表达
Expression of P21 and P53 protein in hippocampus of rats after ischemia reperfusion following chronic cerebral hypoperfusion
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ICAM-1在移植心脏缺血再灌注损伤中的表达及意义
The Expression and Significance of ICAM-1 on Myocardial Reperfusion Injury after Cardiac Transplantation in Rats
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方法健康雄性SD大鼠54只,线栓法制作大鼠大脑中动脉缺血再灌注模型。
Methods 54 healthy male SD rat models with middle cerebral artery occlusion and reperfusion were made by suture method .
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方法用Wistar大鼠腹腔内注射链脲佐菌素,建立超负荷糖尿病大鼠模型,之后做大脑中动脉脑缺血再灌注模型。
Methods Hyperglycemia model was made by injection of streptozocin through abdomen in Wistar rats ; Cerebral ischemia ;
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三七三醇皂苷对局灶性脑缺血再灌注大鼠脑组织Nestin表达的影响
Effects of PTS on Expression of Nestin following Focal Ischemia-Reperfusion in Rats
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目的:探讨促凋亡蛋白Bid在模拟缺血再灌注乳鼠心肌细胞凋亡中的作用及其可能的机制。
Objective To study the role of Bid in simulated ischemia / reperfusion injury in cultured neonatal rat cardiocytes and its possible mechanism .
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针刺对全脑缺血再灌注大鼠外周血WBC和细胞因子的影响
The Effect of Acupuncture on Peripheral Blood WBC and Cell Factors in Cerebral Ischemia Reperfusion
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三七总皂苷对大鼠脑缺血再灌注损伤血清IL-8的影响
Effect of Panax Notoginseng Saponins on the Content of IL-8 in Serum After Cerebral Ischemia-Reperfusion in rat
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大鼠脑缺血再灌注PAF、PAF受体基因表达的变化
Expression of platelet activating factor receptor gene during focal reversible ischemia of rat brain
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IKK-NF-κB通路在肝脏缺血再灌注复合内毒素血症损伤中的作用及PDTC的保护机制
The Role of IKK-NF - κ B Pathway during Hepatic Ischemia Reperfusion Endotoxemia and Protective Effect of PDTC in Rats
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目的观察异丙酚对离体大鼠全心缺血再灌注损伤心肌c-fos基因表达的影响,探讨其对缺血再灌注损伤心肌保护作用机制。
Objective To study the protective effects of propofol on isolated rat heart during global myocardial ischemia-reperfusion .
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利用沙土鼠脑缺血再灌注动物模型,研究脑缺血和再灌注时红细胞免疫粘附功能(redcellimmuneadherence,RCIA)的变化与脂质过氧化的关系。
This experiment studied the functional changes of red blood cell immune adherence ( RCIA ) and lipid peroxidation during cerebral ischemia-reperfusion in gerbil .
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总丹酚酸亦增强缺血再灌注小鼠脑组织SOD的活性,降低MDA含量,增加GSH的含量。
The total salvianolic acid also significantly inhibited the changes of SOD , MDA and GSH in the cerebrum induced by ischemia reperfusion .
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目的探讨bcl-2基因对供体小肠缺血再灌注损伤的调控作用及机制。
Objective To investigate the effect of the regulation of the bcl-2 gene on the ischemia reperfusion injury of donor intestine and the mechanism .
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灯盏花素对缺血再灌注沙土鼠海马ATP含量变化和兴奋性氨基酸释放的影响
Effects of erigeron on ATP content and release of excitatory amino-acids of the hippocampus after cerebral ischemia / reperfusion injury in gerbils
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Caspase-3在大鼠心肌缺血再灌注损伤中的作用及药物干预研究
The Study of the Role of Caspase-3 on Apoptosis During Myocardial Ischemia Reperfusion in Rats and the Effect of Ac-DEVD-CHO
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结果三型NOS在缺血再灌注12、24、72h后与正常对照组比较均明显增加。
Result The expression of three types NOS increased significantly than control after reperfusion 12h , 24h and 72h .
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针刺不同穴组对全脑缺血再灌注大鼠TNF-α、IL-6、WBC和自由基的影响
Effects of Electroacupuncture of Different Acupoint Groups on Blood TNF - α、 IL-6 、 WBC and Cerebral Free Radicals in Cerebral Ischemia-Reperfusion Rats
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结果:心肌缺血再灌注后心肌梗死范围明显,血浆CK活性增高,心肌细胞坏死增多。
Results : Myocardial infarct size enlarged and serum CK level elevated and the number of myocyte necrotic cell in creased in MIR group .