美洛西林

美洛西林钠的HPLC测定

HPLC determination of mezlocillin sodium

方法：A组35例，用美洛西林6～9g·d1静脉滴注，分2或3次给药；

Methods : 35 cases in A group received intravenous infusion mezlocillin , 6 ~ 9 g · d - 1 in 2 ~ 3 divided doses ;

目的：考察不同温度（25℃、37℃）下6h内，美洛西林钠与木糖醇的配伍稳定性。

Objective : To study the stability of compatibility of mezlocillin sodium in 5 % xylitol injection at different temperature ( 25 ℃、 37 ℃) winthin six hours .

鲎试剂检查注射用美洛西林钠/舒巴坦钠细菌内毒素的探讨

Bacterial Endotoxin Test of Mezlocillin Sodium / Sulbactam Sodium for Injection

美洛西林钠是一种新型半合成青霉素。

Mezlocillin sodium is a new kind of important semi-synthetic penicillin .

美洛西林治疗呼吸道感染54例

Efficacy of mezlocillin in treatment of respiratory tract infections in 54 patients

由于美洛西林有一定的市场优势，开发它是有前途的。

As it possesses market advantages , the development of mezlocillin is promising .

美洛西林血清杀菌与美洛西林/舒巴坦效价研究

Serum Bactericidal Activities of Mezlocillin and Mezlocillin / sulbactam : A Comparative Study

结论美洛西林可作为治疗淋病的有效而安全的抗生素。

Conclusion The mezlocillin is an effective and safe antibiotic in treatment of gonorrheae .

高效液相色谱外标法测定注射用美洛西林钠的含量。

A HPLC method for the determination of mezlocillin sodium for injection was established .

鲎试剂法检测注射用美洛西林钠的细菌内毒素

Study on the Determination of Bacterial Endotoxin In Mezlocillin Sodium for Injection By Tachypleus Amebocyte Lysate

美洛西林与哌拉西林随机对照治疗下呼吸道细菌感染的临床研究

A Randomized Comparative Clinical Study of Mezlocillin Versus Piperacillin in the Treatment of Lower Respiratory Tract Bacterial Infections

哌拉西林/舒巴坦与美洛西林/舒巴坦治疗呼吸道感染的疗效比较

Comparison of the effect of piperacillin / sulbactam and mezlocillin / sulbactam in the treatment of acute respiratory infection

将此法用于生物体液中美洛西林钠的测定，结果令人满意。

The method has been applied to the measurement of mezlocillin sodium in the biological fluids with satisfactory results .

美洛西林/舒巴坦体内外杀菌活性及其对感染性疾病临床疗效评价

In Vivo and in Vitro Antibacterial Activities of Mezlocillin / Sulbactam and Evaluation of Its Clinical Efficacy Against Infectious Disease

对抗生素敏感≥40%的抗生素为羧苄西林、美洛西林、甲氧苄啶、头孢他啶、替卡西林、替卡西林/克拉维酸。

Antibiotics with more than 40 % sensitivity rates were carbenicillin , mezlocillin , trimethoprim , ticarcillin , ticarcillin / clavulanic acid .

目的：分析美洛西林所致不良反应的特点，为临床合理用药提供参考。

OBJECTIVE : To analyze the characteristics of mezlocillin-induced ADRs so as to provide references for the rational use of drugs in the clinic .

结论：美洛西林在治疗呼吸道和泌尿道感染方面优于头孢呋辛，是一种成本-效果较好的药物。

CONCLUSION : Mezlocillin is better than cefuroxime in the treatment of bacterial infections in respiratory and genitourinary systems , and is a good cost-effect drug .

目的对比哌拉西林/舒巴坦（试验药）与美洛西林/舒巴坦（对照药）对急性细菌性呼吸道感染的临床疗效及细菌学疗效。

Objective To observe the comparison of the clinical effect and bacteriological effect of piperacillin / sulbactam ( trial drug ) and mezlocillin / sulbactam ( contrast drug ) in the treatment of acute respiratory infection .

结果美洛西林组的痊愈率（75%）略高于头孢呋肟组（70%）、有效率均为100%；

Results It was showed that the cure tate in mezlocillin group ( 75 % ) was higher than that in cefuroxime group ( 70 % ) and the effective rates in both groups were 100 % .