聚乙醇酸
- 网络Polyglycolic Acid;pga;PLGA;polyglycolide;Dexon
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通过聚乳酸(PLLA)、聚乙醇酸(PGA)的复合纺丝,获得一种新的皮芯复合纤维,并对纤维拉伸特性和微观结构进行探讨。
A new core-sheath conjugate fiber was obtained through PLLA and PGA conjugate spinning , and the tensile properties and micro-structure were discussed .
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目的:了解单纯聚乙醇酸和聚乳酸共聚物(PLGA)以及经Ⅱ型胶原表面修饰后的PLGA,对诱导后的骨髓间充质干细胞(MSC)粘附、增殖及分化的影响。
Aim : To investigate the effects of PLGA and PLGA modified by Collagen ⅱ on the adhesion and differentiation in the induced mesenchymal stem cells ( MSCs ) .
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方法:纯度为99%的川芎嗪单体、甲基丙烯酸甲酯共聚物和聚乙醇酸均匀喷涂于金属裸支架上,制成含川芎嗪200μg的涂层支架。
Methods : Bare metal stents were uniformly sprayed painting with Tetramethylpyrazine monomer ( 200 μ g )、 methyl methacrylate copolymer and polyglycolic acid , and prepared Tetramethylpyrazine-eluting stents .
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目的探讨在高脂内环境下聚乙醇酸(PGA)可降解血管外支架对自体移植静脉(VG)再狭窄的防治作用。
Objective To investigate preventive effect of the polyglycolic acid ( PGA ) biodegradable external stent on restenosis of autologous vein graft in hyperlipemia rabbits .
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取新生SD大鼠背根神经节与人工材料聚乙醇酸纤维联合培养3周,倒置显微镜与扫描电镜观察。
The coculture of dorsal root ganglia from 13 d SD rat with artificial material of polyglycolic acid filament were performed for 3 weeks , and observed under inverted phase contract microscope and scanning electron microscope .
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目的探讨联合应用兔骨髓基质干细胞(MSCs)、聚乙醇酸(PGA)支架材料和成骨诱导因子在旋转式细胞培养系统(RCCS)中构建组织工程化骨的可行性。
Objective To explored the possibility of construction of tissue engineered bone in the rotary cell culture system ( RCCS ) using marrow stromal stem cells ( MSCs ) with polyglycolic acid ( PGA ) and osteogenic inducing factors .
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胶原膜、聚乙醇酸/聚乳酸共聚物在组织工程心脏瓣膜支架材料中的应用
Preliminary study on collagenous film and PGLA applying to tissue engineering heart valve
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胶原膜和聚乙醇酸/聚乳酸共聚物构建组织工程心脏瓣膜的对照研究
Fabrication of heart valve with collagenous film and PGLA by using tissue engineering
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聚乙醇酸支架组织工程神经复合物修复大鼠脊髓损伤
Repair of acute spinal cord injury in adult rats by constructing tissue-engineered neural complex
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骨髓基质干细胞接种于聚乙醇酸支架中异位成骨的观察
Marrow stem cells seeded into polyglycolic acid scaffold to restore new bone in vivo
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多聚乙醇酸-羟基磷灰石复合体为支架的骨髓基质细胞修复兔关节软骨缺损
Repair of articular cartilage defects by bone marrow derived mesenchymal cells combined with hydroxyapatites-polyglycolic acid composite
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壳聚糖管与聚乙醇酸纤维复合移植修复大鼠坐骨神经缺损研究
Experimental study of repair of sciatic nerve gap in rat by chitosan tube and polyglycolic fiber
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探索人工生物降解材料聚乙醇酸纤维与周围神经组织的生物相容性。
To investigate the biological compatibility of artificial material of polyglycolic acid with peripheral nerve tissue .
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使用聚乙醇酸/聚乳酸镀膜铂金属圈治疗破裂或未破裂的脑动脉瘤患者:一项单中心试验
Polyglycolide / polylactide-coated platinum coils for patients with ruptured and unruptured cerebral aneurysms : A single-center experience
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本研究评估使用交联聚乙醇酸棒开放复位内固定治疗骨软骨骨折。
This study assessed open reduction and internal fixation of the osteochondral fragments with use of multiple polyglycolic acid rods .
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目的将骨髓基质干细胞接种于聚乙醇酸支架中,进行异位骨再造的研究。
Objective New bone restoration by marrow stem cells ( MSCs ) seeded into polyglycolic acid ( PGA ) scaffold was studied .
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体外联合培养结果提示,人工生物降解材料聚乙醇酸与大鼠周围神经组织有较好的生物相容性。
Experimental study of coculture in vitro showed that there had good biological compatibility between artificial biodegradable material of polyglycolic acid and peripheral nerve tissue of rat .
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并以辛酸亚锡为引发剂,采用本体开环聚合反应成功地合成了聚乙醇酸、乙交酯/丙交酯及乙交酯/ε-己内酯等聚合物。
Details of the synthesis polyglycolic acid ( PGA ) were described , as well as a series of glycolide / latide and glycolide / ε - caprolactone copolymers by a ring-opening polymerization of glycolide , lactic and e - caprolactone upon initiation with an appropriate amount of stannous octoate .
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聚乳酸乙醇酸(PLGA)是一种可降解的高分子聚合物,其对药物具有缓释作用,且有较好的生物相容性。
PLGA is a kind of degradable high molecular polymer with good biocompatibility . Drug connected have the function of control release .
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材料有聚乳酸乙醇酸共聚物,溶菌酶,聚乙烯醇,其他试剂均为分析纯。
The other reagents were analytical pure .
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方法采用乳化-分散法,将可生物降解高分子聚乳酸/乙醇酸共聚物(PLGA)对VEGF进行包裹,合成可缓慢释放的微粒。
Methods The method of emulsification-diffusion was to incorporate VEGF into microparticles that composed of biodegradable PLGA , and the controlled release of microparticles were acquired .
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以可生物降解材料聚乳酸聚乙醇酸共聚物(Poly-dl-lactic-co-glycolic,PLGA)为原料,采用多相乳化技术制备载VEGF纳米粒子。
VEGF nanoparticle ( VEGF-NP ) was prepared by a multi-emulsification technique using a biodegradable poly-dl-lactic-co-glycolic ( PLGA ) as matrix material ?
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海藻酸壳聚糖聚乳酸羟乙醇酸复合微球的制备及其对蛋白释放的调节
Preparation of alginate-chitosan-poly ( lactic-co-glycolic acid ) composite microsphere and its regulation of protein release
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目的:了解二丙酸倍氯米松聚乳酸聚乙醇酸纳米微囊体内分布和释药情况。
Objective : To investigate the kinetics and distribution of beclomethasone dipropionate nanocapsule in vivo .
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方法:在一定的温度和压力下,采用配位-插入聚合法通过交酯开环合成聚乳酸-乙醇酸共聚物缓释材料。
METHODS Under specified temperature and press , adopt coordination-insertion mechanisms by a ring-opening polymerization process .
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聚乳酸-乙醇酸的合成及在药物缓释微球中的应用
Studies on the direct synthesis of poly ( lactic acid-glycolic acid ) and its application in drug delivery microspheres
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方法应用聚乳酸聚乙醇酸共聚物和聚乙烯醇包载特异性反义单核细胞趋化蛋白1基因,制备纳米级粒子混合物。
Methods Nanoparticle DNA complex was prepared with PLGA bearing antisense monocyte chemotactic protein 1 ( A MCP 1 ), a specific expression gene , and the package efficiency , release progress in vitro , and size of the complex were determined .
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HPLC测定雷帕霉素聚乳酸-聚乙醇酸纳米粒的包封率
Determination of Encapsulation Efficiency of Rapamycin-loaded Poly ( lactic-co-glycolic ) acid Nanoparticles by HPLC
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方法建立Silybin含量测定的高效液相色谱方法;以Silybin为模型药物,聚乳酸-聚乙醇酸(PLGA)为载体材料,结合快速膜乳化-溶剂萃取/挥发法制备SilybinPLGA微球。
Silybin as the model drug and PLGA as the carrier material , Silybin PLGA microspheres were prepared by premix membrane emulsification-solvent extraction / evaporation method .
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目的研究食管上皮细胞在聚乳酸-聚乙醇酸[poly(lactic-co-GlycolicAcid),PLGA]三维支架材料上的黏附和生长情况,探索利用组织工程技术构建组织工程食管的可行性。
Objective To verify adhesion and growth ability of canine esophageal epithelial cells ( EECs ) on the poly ( lactic-co-glycolic acid )( PLGA ), a three-dimensional biodegradable polymer scaffold , and to reconstruct the canine esophagus by the tissue engineering .