葛根素

葛根素与DNA的作用机理也进行了探讨。

The mechanism for the binding of puerarin to DNA is also studied .

葛根素对抗H2O2引起血管平滑肌细胞凋亡及坏死

Inhibition of Puerarin on the H_2O_2-induced Apoptosis of Smooth Muscle Cells

葛根素对不稳定心绞痛患者血小板颗粒膜蛋白、溶酶体膜蛋白及血浆纤溶酶原激活物抑制物、C反应蛋白的影响

Effect of Puerarin on Platelet Activating Factors CD63 and CD62P , Plasminogen Activator Inhibitor and C-reactive Protein in Patients with Unstable Angina Pectoris

葛根素及其衍生物对实验性SD大鼠急性血瘀症血液流变学的影响

Effects of Pur and Derivatives on Hemorheology of Acute Blood Stasis in Rats

葛根素对过氧化氢诱导鼠晶状体上皮细胞NF-κB活化表达的抑制作用

The inhibitory effect of Puerarin on the expression and activation of NF - κ B induced by hydrogen peroxide in rat lens epithelial cell

RP-HPLC测定益脑复健胶囊中葛根素的含量

Content determination of the puerarin in Yi'nao Fujian Capsules by RP-HPLC

葛根素对凝血酶诱导的血管平滑肌细胞增殖及凝血酶受体mRNA表达的影响

Effects of puerarin on thrombin-induced-proliferation of vascular smooth muscle cells and the role of puerarin on the TR mRNA expression

葛根素和丹酚酸B是两个传统的活血化瘀中药，具有明显的抗血小板聚集，抑制血栓形成的作用，广泛用于缺血性心脑血管疾病。

Traditional Chinese medicine , Puerarin and salvianolic acid B , have significant antiplatelet and antithrombotic activity , and widely used in ischemic heart and cerebrovascular diseases .

葛根素对球囊损伤血管内皮后血小板活化及血管紧张素Ⅱ1型受体mRNA变化的影响

The effects of puerarin on platelet activation and expression of angiotensin ⅱ AT_1 receptor mRNA after vascular balloon injury in rats

与用普通溶剂结晶相比，发现采用超临界CO2结晶所得葛根素的溶剂残留最少、与中国药典中的标准红外光谱最为接近、品质更优。

Compared with normal solvents , crystal from super critical fluid extraction had the fewest residue solvents ; best quality and shape ;

葛根素对兔肺缺血再灌注损伤时Bcl-2、Bax及caspase-3的影响

Effect of puerarin on Bcl-2 , Bax and caspase-3 in rabbit lung ischemic reperfusion injury

本文运用配位化学的基本原理，采用pH电位滴定法，对葛根素的配位特性进行研究。

According to the basic principle for complex chemistry , the complex character of puerarin with metal ions was studied by pH-potentiometric titration method .

目的建立HPLC测定犬口服复方葛根制剂后葛根素的血药浓度。

AIM A RP-HPLC method was developed to determin puerarin ( Pur ) in dog plasma after administering Puerarin lobata recipe .

葛根素对高血压缺血性脑卒中血ET-1，SOD，MAD的影响

Effects of Puerarin on blood ET-1 , SOD , MDA in the patients with stroke or hypertension

葛根素对肾缺血/再灌注时肾小管上皮细胞c-Fos蛋白表达的影响

Effects of puerarin injection on c-Fos protein of renal tubule cells during ischemic-reperfusion in kidney

葛根素在CTAB胶束体系中的酸碱平衡研究

Acid-Base Equilibrium of Puerarin in CTAB Micelles

葛根素对实验性脑缺血GAD、VEGF表达变化的影响

Effects of Puerarin on the Expression of GAD 、 VEGF After Experimental Cerebral Ischemic Damage in Rats

葛根素对糖尿病大鼠肾功能及肾组织MMP-2与TIMP-2表达的影响

Effects of puerarin on renal function , expressions of MMP-2 and TIMP-2 in diabetic rats

葛根素对大鼠肠缺血再灌注的肠黏膜iNOS基因表达的影响

Effect of puerarin on the expression of iNOS gene in the gut mucosa of intestinal ischemia-reperfusion rats

葛根素及其磷脂复合物在Beagle犬体内的药动学比较

Comparison of pharmacokinetics between puerarin and its phospholipid complex in Beagle dogs in vivo

根据葛根素收率、HPLC图谱，筛选洗脱剂的浓度、洗脱方式；

According to the yield of puerarin and the figure of HPLC , the concentration of the eluent and the procedure of the elution were chosen .

方法利用大鼠在体肠吸收模型，以HPLC法测定不同纯度葛根素提取物中葛根素的小肠吸收情况，计算动力学参数。

METHODS Rats were cannulated for in situ recirculation , HPLC was used to determine the parameters of the absorption kinetics of different purities of puerarin extracts .

葛根素及其纳米粒在Caco-2细胞模型的吸收机制研究

Study on Absorption Mechanism of Puerarin and Its Nanoparticles across Caco-2 Cell Model

葛根素的药理研究&Ⅴ.葛根素对人和动物血小板聚集性和5-HT释放的影响

Pharmacological Studies on Radix Puerariae & ⅴ . Effects of Puerarin on Platelet Aggregation and Release of 5-HT from Platelet

CBN中葛根素、人参皂苷Rg1的高效液相色谱测定法及其在脑缺血再灌大鼠体内的药代动力学

High-performance liquid chromatographic determination of puerarin and ginsenoside Rg1 in rat plasma : application to pharmacokinetic studies

目的建立RP-HPLC法测定葛根素长循环脂质体中葛根素的含量和包封率。

OBJECTIVE To establish an RP-HPLC method for determining the content of puerarin in Puerarin long circulating liposome and its entrapment efficiency .

以Caco-2细胞为模型考察了葛根素在肠粘膜的透过性。葛根素在Caco-2细胞的转运呈现较强的方向性，随着葛根素浓度的增加，其表观渗透率（PDR）降低（2.1～1.4）。

The Caco-2 cell model was used to study the transport of puerarin across the intestinal membrane .

葛根素对高脂血症大鼠脂质代谢及血浆PGI2、TXA2水平的影响

Effects of puerarin on the levels of PGI_2 and TXA_2 in plasma of rats with hyperlipidemia

目的研究高脂饮食喂养的胰岛素抵抗（IR）大鼠骨骼肌中蛋白激酶B（PKB）表达和葡萄糖转运蛋白4（GluT4）转位的改变及饮食治疗、葛根素、罗格列酮干预的影响。

Objective To study the changes in PKB expression and GluT-4 translocation in skeletal muscle of insulin resistant rats fed with high fat diet and the effect of intervention treatments .

取72只雄性SD大鼠随机分为假手术组、缺血对照组、葛根素组曲克芦丁组4组各18只。

Seventy-two SD male rats were randomly divided into 4 groups : sham operation group , ischemia control group , kakonein group and troxerutin group with 18 rats in each group .