germline

More important is strict enforcement of a moratorium on clinical use of germline editing .

更重要的是，应严格执行对种系编辑临床应用的禁令。

The Advance of Embryonic Stem Cells and Germline Chimeras

胚胎干细胞及种系嵌合体的研究进展

Finally I should say a word about germline gene therapy .

最后，我应当提一句生殖系基因疗法。

The Chicken Germline Stem Cells Culture and Testicular Tissue Transplantation

鸡生殖系干细胞培养与睾丸组织移植研究

Prepubertal Mice Female Germline Stem Cell Isolation , Cell Line Establishment and Characterization

青春前期小鼠雌性生殖干细胞的分离、建系和鉴定

Signal Transduction in the Proliferation of Germline Stem Cell

生殖干细胞增殖中的信号转导

Mechanism of Nuclear Membrane Protein Determines the Fate of Germline Stem Cells in Drosophila

核膜蛋白决定果蝇生殖干细胞命运的作用机制

The new germline stem cells displayed all the markers indicative of fully mature sperm .

新的生殖干细胞显示完全成熟的精子的所有标记。

Nine kinds of malignant lymphoma cell lines and normal germline DNA using southern blotting technique were compared .

淋巴瘤为恶性克隆起源的血液病，Ig基因的重排测定可以帮助其分型和预示早期复发.本文用Southern印迹技术分析人9种恶性淋巴瘤细胞系，并于正常胚系DNA比较。

This experiment shows this EG cell line is pluripotent , germline transmission remains to be confirmed .

结果表明该EG细胞系具有多能性，是否可以进入种系有待进一步验证。

Cloning and Characterization of Two JH and C μ Ig Genes in Bovine Germline Gene

牛胚系基因中两种JH和Cμ抗体基因的克隆与分析

Once a germline mutation is determined in a family , it is easy to conduct gene diagnosis and risk prediction .

在一个家系中一旦确定RB基因生殖细胞性突变，则很容易对患者同胞及子女作出明确基因诊断与风险预测。

Expression of GATA-2 Gene and Immunoglobulin Heavy Chain Germline Gene C_ μ in Leukemia Cells and Its Significance

GATA-2与免疫球蛋白重链胚系基因Cμ在白血病细胞中的表达及其意义

Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis

与家族性胃肠道间质瘤及肥大细胞病相关的KIT的新种系变异

Somatic mutation & A mutation occurring in a somatic cell rather than in the germline .

发生在体细胞而非种系中的可遗传的变异。

Association of the Germline Mutations of E-Cadherin Gene ( CDH1 ) in Gastric Cancer

E-Cadherin（CDH1）基因胚系突变与胃癌风险的研究

Most cell lines maintained normal karyotype and expressed markers of pluripotency , including germline transmission in chimeric mice .

经ES细胞鉴定，结果表明大部分ES样细胞系保持正常的核型并表达多能性的标志分子，可以在嵌合体小鼠中进行生殖系传递。

Two copies of JH and C μ genes in the bovine germline may contribute to the antibody diversification as well .

双拷贝JH，Cμ基因的存在可能是牛抗体多样性产生的新的基因来源。

In the policy realm , one of the most important decisions we humans will have to make is whether to allow germline gene modification .

在政策领域，我们人类必须做出的一个最为重要的决定：是否允许修正人类生殖细胞基因。

Here we are looking at male germline mutations , which are mutations in the DNA of sperm .

我们在这里是看男胚系突变，其中突变，在基因的精子。

Genomic instability involving structure alterations and epigenetic effect stems from germline and somatic mutation and related to genetic susceptibility of cancer .

基因组不稳定性与癌的遗传易感性相关，涉及基因组结构改变和表遗传效应，来源于胚系突变和体细胞突变。

With further research , the method can be improved and used to produce somatic and germline chimeric chickens efficiently and enable the production of transgenic birds .

通过后续研究，我们可以改善这种方法，用于有效生产体细胞和生殖细胞嵌合的鸡和转基因禽类。

We hypothesized that germline variation contributes to MPN predisposition and phenotypic pleiotropy .

我们推测种系变异可促进MPN易感及表型多向性。

In warmer climates annual metabolic activity is likely to be greater , so this will lead to more total cell divisions per year in the germline .

在较温暖的气候，每年新陈代谢活动可能更剧烈，所以，在生殖系上会产生出更多的细胞分裂。

The nanos gene encodes a Zinger-finger protein , it plays critical role in maintaining the totipotency of germline stem cells .

nanos基因编码一个具有锌指结构的蛋白，在生殖干细胞全能性调控方面起着重要作用。

Throughout the cell cycle , centrosomes in germline stem cells ( GSCs ) are oriented within their niche and this ensures asymmetric division .

在细胞周期整个过程中，干细胞在微环境中确定中心体取向，决定了细胞的不对称分裂。

There are germline polymorphisms lying in all of the three genes that can cause significant decrease of enzymes expression and might have solid impact on genetic susceptibility of COPD .

以上三种基因均存在显著影响产物表达水平的多态现象，从而推测这些重要的多态改变能够影响中国人COPD的遗传易感性。

Instead , every time a germline stem cell divides by meiosis to make sperm in adults the jumping genes are activated only to be silenced soon thereafter .

而且在成体中生殖系干细胞产生精子的每一次减数分裂都伴随着跳跃基因的活化，而活化后很快就被沉默。

The Research of Gene Targeting of the Bovine Immunoglobulin Heavy Chain JH , E μ Locus and Analysis of JH , C μ Genes in the Bovine Germline Gene

牛免疫球蛋白重链基因中JH，Eμ片段敲除的研究和JH，Cμ基因的分析

According to reports , ESC culture in vitro was more than two years and attained 450 serial passages . Embryonic germline ESC attained 70 ~ 80 passages at most .

据报道，ES细胞目前已有在体外培养两年，连续传代达450次以上，而胚胎生殖干细胞传代次数最多可达70~80次。