亲脂性
- 名lipophilicity
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CsA的分子量大、亲脂性强、水溶性低、口服生物利用度较低[2,3]。
Due to its great molecular weight , strong lipophilicity , low water-solubility and low oral bioavailability , the effects and applications of CsA have been seriously affected .
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目的测定左氧氟沙星的质子解离平衡和亲脂性。
Aim To determin the protonation equilibrium and lipophilicity for levofloxacin .
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其C端有一段25个氨基酸组成的片段具有亲脂性和跨膜特性。
The first 25 amino acid residues at C terminal form had hydrophobic trans-membrane helix .
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两者都有一个跨膜螺旋结构N末端20个氨基酸具有信号肽的特征,C末端25个氨基酸具有明显的亲脂性,并且具有跨膜特征。
Both of them have one transmembrane helix structure . The first 20 amino acid residues at C-end is hydrophobic transmembrane helix .
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蒲黄炒炭前后亲脂性成分的GC-MS分析
GC-MS analysis of the fatty components of Pollen Typhae before and after being carbonized
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另外,DCS中碳水化合物的含量明显高于亲脂性抽出物与合成聚合物,而合成聚合物的含量相对比较低。
Furthermore , the content of carbohydrate was much higher than that of lipophilic extractives and synthetic polymers .
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一元醇亲脂性基于理论线性溶解能相关的QSPR研究
QSPR research on the lipophilicity of monohydric alcohols based on theoretical linear solvation energy relationship
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研究结果表明由酚类化合物引起的DNA损伤可用有机物的亲脂性参数KOW和分子折射率MR很好地表征。
, were established . The results showed that the DNA damage by phenols was correlated well with the logarithm of octanol / water partition coefficient ( logKOW ) and molecular refractivity MR.
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壬基酚属于内分泌干扰物(EDCs),在环境中具有亲脂性、高毒性和持久性,被定义为持久性有机污染物(POPs)。
Nonylphenol , an endocrine disrupter contaminants with high lipotropy , toxicity and persistent characteristics , is defined as persistent organic pollutants .
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本实验采用两种不同的合成方法用亚油酸和α-亚麻酸修饰Cu,Zn-SOD,以期提高SOD的稳定性和亲脂性。
In this study , Chemically modified Cu , Zn-superoxide dismutase ( SOD ) with linoleic acid and α - linolenic acid were achieved through two different synthetic methods to improve the stability and lipophilicify .
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采用石英晶体微天平现场技术,研究了胆红素在纳米TiO2表面的吸附动力学行为,并考察了溶液pH、硅烷亲脂性试剂及金属离子修饰的纳米TiO2对胆红素吸附的影响。
In_situ technique of quartz crystal microbalance was employed to study the adsorption behavior of bilirubin on nanocrystalline titania films , and effects of pH of bilirubin solution , surface modification of TiO_2 with silane coupling agent and metal ions were investigated .
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TMT具有较强的亲水性和亲脂性,极易通过消化和皮肤黏膜进入机体,对水生生物产生毒性并在体内富集,因此极有可能对水生生物造成潜在危害。
Because of the TMT having both hydrophilic and lipophilic , it could enter organism through digestion and skin easily , generate toxicity to aquatic organisms and be accumulated in the body .
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结果表明,SPMD能够用模拟鱼从水体中亲脂性富集硝基芳烃化合物的过程,富集系数和化合物正辛醇/水分配系数相似;
Our results showed that the accumulation of the nitroaromatics in SPMD and in fish was compared and good correlation between device concentration factor and the octanol / water distribution coefficients of the compounds .
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亲脂性修饰对小檗碱体内调脂活性的影响
Influence of lipophilic structure-modification on lipid-modulating effect of berberine in vivo
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结论月桂酰吲达帕胺为弱酸性亲脂性药物。
Conclusions Lauroyl indapamide is a weak acid with lipophilic property .
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肝型脂肪酸结合蛋白与亲脂性药物的相互作用的研究
The Interaction of Lipophilic Drugs with Liver Fatty Acid Binding Protein
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亲水/亲脂性附加剂对乳酸-羟乙醇酸共聚物微球中蛋白释放的影响
Effect of hydrophilic / hydrophobic additives on protein release from PLGA microspheres
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对甾体类生物碱的提取,按照不同的文献方法,采取不同的提取步骤,整体来讲是采用醇类提取和亲脂性有机溶剂提取法。
But as a whole methods of alcohol-extraction and lipophilic-organic-solvent have been adopted .
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结论9位引入亲脂性芳基增强了小檗碱的抗菌活性。
Conclusion Introduction of lipophilic aryl in9-position of berberine increases its antibacterial activities .
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亲脂性盐对中性载体钙离子选择性微电极性能的影响
Effect of Lipophilic Salts on the Performance of Neutral Carrier-Based Calcium Selective Microelectrodes
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由于大部分的迁移物具有亲脂性,迁移发生最厉害的情形通常出现在脂肪食品与包装材料的接触过程中。
Since most potential migrations are lipophilic , worst cases usually occur with fatty foodstuffs .
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结果显示活性物质是一种大分子的亲脂性物质。
The result suggested that the active substance be a low molecular weight substance with liposolubility .
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目的分析卷丹及其水提液中亲脂性成分。
OBJECTIVE To analyze the categories of Dahurian Lily and the lipophilic components in its water extract .
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松花粉和松针提取物在亲脂性体外模型系统中抗氧化能力和机制的研究
Study on the antioxidant properties and mechanism of pollen and needle extracts from pinus massoniana in lipophilic model system
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应用亲脂性阴离子荧光染料DiBAC4(3)标记小鼠腹腔巨噬细胞,以粘附式细胞仪观察虎杖甙对腹腔巨噬细胞膜电位的影响。
Con focal microscopy was performed to study the effects of Polydatin on the membrane potential in intraperitoneal macrophages .
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结论:磷脂的加入可有效提高柚皮苷的亲脂性,改善机体对其吸收,从而提高其成骨细胞活性。
CONCLUSION : The main activity of phospholipids on phospholipids complex is to promote the absorption of the cell .
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细胞内受体介导亲脂性信号分子的信息传递,如胞内的甾体类激素受体。
Cell receptor-mediated lipophilic signal molecule in the transmission of information , such as cell within the steroid hormone receptors .
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紫花松果菊亲脂性化学成分研究(Ⅱ)热固性丙烯酸粉末涂料&Ⅱ.树脂的合成
Study on the lipid compounds from Echinacea purpurea Thermosetting Acrylic Coating Powder & ⅱ . The Synthesis of Acrylic Resins
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自乳化药物传递系统对于亲脂性和难溶性药物是一个非常有希望的新型载体系统。
Self emulsifying drug delivery systems ( SEDDS ) is a new potential delivery system for lipophilic or poorly soluble drugs .
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目的:对松花粉和松针提取物在亲脂性抗氧化模型系统中的抗氧化能力和机制进行研究。
Objective : Antioxidant capacity and relative mechanism of pollen and needle extracts from pinus massoniana were evaluated in lipophilic model system .