压力负荷

ALT-711对压力负荷诱导的舒张性心力衰竭大鼠心脏功能的影响

Effect of ALT-711 on Cardiac Function in Rats of Diastolic Heart Failure Induced by Pressure Load

解偶联蛋白-2基因在压力负荷模型大鼠心肌中的动态表达变化

The Expression of UCP_2 Gene in Myocardium with Pressure Load in Rats

负荷过重的心脏，可能承担额外的压力负荷或容量负荷。

The overburdened heart may be carrying an extra pressure or volume load .

大鼠压力负荷性肥大心肌中TNF-αmRNA表达变化

Expression of TNF - α mRNA in hypertrophic myocardium by pressure overload in rats

cDNA芯片法筛选压力负荷型心肌肥厚相关基因

Identification of genes related to mechanical load-induced cardiac hypertrophy by cDNA chip

压力负荷增加大鼠模型心肌α-MHC和β-MHCmRNA的表达

Expressions of myocardial α - MHC and β - MHC mRNA in rats with pressure overload

COPD缓解期患者阈压力负荷吸气肌锻炼的疗效观察

Effects of threshold loading device for inspiratory muscles training in patients with COPD

结论：压力负荷增加大鼠心肌Ⅰ和Ⅲ型胶原及其mRNA的表达增加；

CONCLUSION : Myocardial collagen type ⅰ and type ⅲ and mRNA expression in rats with pressure overload are increased .

压力负荷性大鼠肥厚心肌中AngⅡ受体的表达

Expression of Ang ⅱ receptors in excess load-pressured hypertrophied cardiac muscles of rats

有研究证明，蛋白酶体抑制可以通过降低NF-κB的活性而减轻压力负荷导致的心肌重构，从一定程度上逆转心肌肥大。

Proteasome inhibitor could reduce the myocardium remodeling caused by pressure overload by inhibiting the activity of NF - κ B , resulting in reverse of cardiomyocyte hypertrophy .

结论：TGFβ1表达增多、MMP-8/TIMP-1表达相对上调可能参与了大鼠压力负荷性心肌重塑的发生和发展。

Conclusion : The expression elevation of TGF β 1 and MMP-8 / TIMP-1 might relate with myocardial remodeling in pressure overload rats .

目的：观察压力负荷增加大鼠心肌Ⅰ和Ⅲ型胶原及其mRNA表达的改变及卡托普利的影响。

Objectives : To observe morphological and mRNA expression changes of myocardial collagen type ⅰ and type ⅲ, and the effect of captopril in rat with pressure overload .

方法利用末端转移酶介导的切口末端标记法（TUNEL）及TEM法，检测慢性压力负荷性心衰大鼠左、右心室心肌的凋亡细胞。

Methods left and right ventricular myocardium of rats with chronic heart failure was used to study apoptosis by TUNEL and TEM methods .

荞麦花叶总黄酮对大鼠急性压力负荷c-fos蛋白表达的影响

Effect of total flavones of buckwheat flower and leaf on c-fos protein expression in course of acute pressure overload in rats

方法采用缩窄腹主动脉造成大鼠压力负荷模型，将大鼠随机分为两组：假手术组（SOG）和手术组（OG）。

Methods Pressure_overload rat model was adopted by constricting the abdominal aorta .

大鼠压力负荷性心肌肥厚时心脏RAS的变化。

Cardiac RAS and myocardial hypertrophy : The pressure overload myocardial hypertrophy was induced in rats by abdominal aortic banding for 6 weeks .

探讨压力负荷增高性心肌肥厚时心肌胶原网络及心肌细胞外基质金属蛋白酶（MMPs）活性的变化。

To examine changes of collagen network and Matrix Metaloproteinases ( MMPs ) activity in hypertrophied rat myocardium .

结论阿托伐他汀能部分防止压力负荷诱导的心肌肥厚时的Cx43重构。

[ Conclusion ] Atorvastatin can prevent partly gap junction remodeling of hypertrophied myocardium induced by pressure overload .

Tei指数评价右心容量和压力负荷过重对房间隔缺损患者心功能的影响

Relation of Tei index to right ventricular volume and pressure overload in patients with atrial septal defect

卡维地洛与压力负荷心衰大鼠心室重塑和Rho激酶表达的关系

Relationship of Carvedilol with Cardiac Remodeling and the Expression of Rho Kinase in Pressure Overload Induced Heart Failure Rats

结论压力负荷性大鼠表达上调的ET1参与心室重构。

Conclusion Over-expressed endothelin-1 gene may contribute to ventricular remodeling in hypertrophied rats .

而钙调蛋白磷酸酶抑制剂则可以阻断压力负荷导致的心肌肥厚的发生，并且还能够减少心肌细胞的APD延长。

And calcineurin inhibitor could prevent myocardium from hypertrophy induced by pressure overload and decrease the prolongation of APD in myocardial cells .

方法：本实验采用腹主动脉缩窄法建立大鼠压力负荷性心肌肥厚模型，用放免法测定MAng及比色法测定NOS含量。

Methods : The pressure overload cardiac hypertrophy model was produced by constriction of abdominal aorta . MAng ⅱ was measured by radioimmunoassay , and NOS by colorimetric method .

目的：观察卡托普利对压力负荷性心肌肥厚大鼠心肌组织中的血管紧张素（MAng）及一氧化氮合成酶（NOS）含量的影响。

Aim : To investigate the effect of captopril on the myocardium angiotensin ⅱ ( MAng ⅱ) and nitric oxide synthase ( NOS ) in rats with pressure overload cardiac hypertrophy .

目的探讨心血管系统压力负荷增加到心肌肥厚形成的过程中血清中肿瘤坏死因子-α（TNF-α）、白介素-1β（IL-β）、白介素-6（IL-6）等细胞因子的变化及意义。

[ Objective ] To investigate the significance of changes in serum tumor necrosis factor - α ( TNF - α), interleukin-1 β ( IL-1 β) and interleukin-6 ( IL-6 ) from the increasing of load to hypertrophy .

而且，压力负荷引起血管活性肽如血管紧张素Ⅱ（AngⅡ）和内皮素-1（ET-1）的分泌和产生，其在诱导肥厚反应中扮演着重要角色。

Furthermore , pressure overload leads to the release of secretion and production of vasoactive peptides , such as angiotensin II and endothelin-1 , which play pivotal roles in the induction of these hypertrophic responses .

目的观察特异性COX2抑制剂对大鼠慢性压力负荷性心肌肥厚过程中左室重构的影响。

Objective To investigate the influence of selective cyclooxygenase-2 inhibitor on rats with pressure overloaded myocardial hypertrophy .

10例COPD患者经松静内养功锻炼4个月后在相同运动强度下呼吸频率减低，呼吸困难减轻，压力负荷呼吸时胸腹矛盾呼吸减轻。提示气功锻炼可改善生活质量。

In 10 COPD patients , who have finished rehabilitative program for 4 months with Qigong , respiratory frequency was reduced at the same exercise strength with ergometer and the paradoxical respiratory motion was improved while threshold pressure loading breathing .

结论是，左心房SEC现象为二尖瓣狭窄患者中常见病理性超声现象，其存在提示左心房容量或压力负荷增加，但并不一定表示左心房内附壁血栓的存在。

We believe that SEC is a common pathological echo phenomenon in left atrium of patient with mitral stenosis . It might be due to the increased diastolic or systolic over-loading of the left atrium , but not necessarily be the sign of left atrium thrombosis .

目的：观察荞麦花叶提取的总黄酮（TFBFL）对大鼠急性压力负荷左心室c-fos蛋白表达的影响。

AIM : To explore the effect of total flavones of buckwheat flower and leaf ( TFBFL ) on the expression of c-fos protein in the course of acute pressure overload of the left ventricle in rats .