以洛伐他汀为原料，三甲基氯硅烷为羟基保护基，用活泼的强亲核试剂叔丁基锂代替当前的吡咯烷锂合成了目标产物新伐他汀，总收率达78%。
It can be synthesized with the material of lovastatin , hydroxy protecting agent of trimethylchlorosilane , and t-butyl lithium instead of pyrrole lithium . The total yield is about 78 % .
叔丁基锂