嗜酸粒细胞

近期的研究提出的迟发相变态反应的概念认为，除了组胺之外，趋化因子、嗜酸粒细胞、Th细胞及其细胞因子在慢性荨麻疹的发病中也具有举足轻重的地位。

Recent researches raise the definition of late-phase allergic reactions . In addition to the function of histamine , chemokines , eosinophil , T lymphocyte and its cytokines also play an important role in the pathogenesis of chronic urticaria .

目的观察哮喘患者急性发作期、缓解期的肺功能和血嗜酸粒细胞（EOS）的变化，探讨其临床意义。

Objective We explore the clinic usage according to observing the change of lung-functions and eosinophil ( EOS ) between the acute-outbreak period and catabatic period of asthma sufferers .

P物质对哮喘患者嗜酸粒细胞的活化和趋化作用

Effect of substance P on the activation and chemotaxis of eosinophils from asthmatic subjects

嗜酸粒细胞可能为鼻息肉中TGFβ1的主要来源。

Eosinophils in nasal polyps represent a major source of TGF β 1 .

砒石对哮喘小鼠信号转导和转录激活因子6及嗜酸粒细胞趋化因子mRNA表达的影响

Effects of arsenolite on expressions of signal transducer and activator of transcription 6 and eotaxin ( mRNA ) in asthmatic mice

雷公藤甲素对哮喘豚鼠嗜酸粒细胞凋亡及Fas，Bcl-2mRNA表达的影响

Effects of triptolide on expression of Fas and Bcl-2 mRNA and apoptosis in eosinophils in asthmatic guinea-pigs

结论ECP是嗜酸粒细胞活化后脱颗粒释放的主要炎性介质，是反映支气管哮喘气道炎症发生发展的重要指标之一。

Conclusion ECP is an important chemokine secreted by activated eosinophil cells .

术前行鼻内镜检查、皮肤点刺变态反应皮试、总IgE及鼻分泌物嗜酸粒细胞涂片检查。

The preoperative examinations included nasal endoscopy , skin prick test , total serum IgE and nasal secretion smear .

结论：RSV毛细支气管炎急性期嗜酸粒细胞增多以后更易发生婴幼儿哮喘。

Conclusion : Eosinophilia at the time of RSV bronchiolitis may predicts the development of asthma in infancy .

目的探讨哮喘患儿免疫球蛋白IgG、IgM、IgA、补体C3、C4和外周血嗜酸粒细胞（PBEC）的含量变化及临床意义。

Objective To explore the change and clinical purpose of asthma chidren 's immune globulin IgG , IgM , IgA , Complement C3 , C4 and eosinophile .

哮喘豚鼠肺组织Eotaxin基因表达与嗜酸粒细胞活化相关

Correlation between eotaxin gene expression and eosinophils activation in lung tissue of asthmatic guinea pigs

目的：探讨嗜酸粒细胞白血病（EoL）的诊断标准。

Objective : To define the diagnostic criteria of eosinophilic leukemia ( EoL ) .

嗜酸粒细胞阳离子蛋白（ECP）对鼻黏膜上皮具有破坏作用，其含量代表Eos的活性。

Eosinophil cationic protein ( ECP ) can injury the nasal epithelium , the contain of ECP may show the activity of Eos .

AR发病过程中，辅助性T细胞、肥大细胞、嗜酸粒细胞、纤毛功能障碍和机体防御机制等对鼻窦炎的发生起了重要作用；

During the course of AR , help T cells , mast cell , eosinophil , disorders of ciliary motility and defense mechanism all have important effects on the occurrence of sinusitis .

嗜酸粒细胞增高或正常者病情轻，预后好，减少或消失者恶化率及病死率明显增高。作者就SAH致WBC改变的机理及相互影响进行了讨论。

Increased or normal eosinophils suggested a mild SAH with a good prognosis , The mortality rate was high when cosinophil was decreased or disappeared .

方法用1%多聚甲醛固定嗜酸粒细胞和支气管上皮细胞系BEAS-2B细胞；

Methods Eosinophils and BEAS-2B cells were fixed with 1 % paraformaldehyde for 1h separately .

口服7d茶碱（1-125mg/kg，bid）可减轻气道炎症（细支气管壁肿胀和肺嗜酸粒细胞浸润），对支气管高反应性也有一定抑制作用。

Oral theophylline ( 1-12.5 mg / kg , bid for 7 days ) attenuated antigen-induced inflammation ( swelling of bronchiole walls and pulmonary eosinophilia ) and bronchial hyperreactivity .

Bcl-xl和Bcl-2在鼻息肉组织嗜酸粒细胞中的表达

The protein expression of Bcl-x_l and Bcl-2 in eosinophils in nasal polyps and the influence of beclomethasone dipropionate on the expression

结论：人脐血CD34+细胞在体外培养条件下经过IL-5和病人血清刺激可早期分化为嗜酸粒细胞。可作为有效的相关研究模型。

CONCLUSION : The allergic patient serum and IL-5 induce differentiation of CD34 ~ + cells in human umbilical blood to eosinophils .

同时应用不同方法测定了其血清总IgE（tIgE）及嗜酸粒细胞阳离子蛋白（ECP）。

Serum total IgE ( tIgE ) and eosinophil cationic protein ( ECP ) were assayed with the Pharmacia CAP system .

生长激素（Growthhormone，GH）是脑垂体前叶嗜酸粒细胞分泌的一种蛋白质激素，其主要生物学效应是直接的代谢作用和间接的促生长作用。

Growth hormone ( GH ) is one kind of protein hormone , which is secreted by eosinophilic granulocyte of anterior pituitary . Its effect at the level of physiological dose is to promote children 's normal growth development .

MIF通过调控嗜酸粒细胞、细胞因子、气道反应性及黏液分泌等参与了哮喘的病理生理过程。

MIF is involved in the pathogenesis of asthma by regulating the eosinophils , cycline and airway hyperresponsiveness as well as mucus excretion .

目的：探讨血清、导痰嗜酸粒细胞阳离子蛋白（ECP）哮喘气道炎症及哮喘严重程度的关系。

AIM : To explore the relationship among serum and induced sputum eosinophil cationic protein ( ECP ), asthmatic airway inflammation and the severity of asthma .

结论母牛分枝杆菌菌苗能减少哮喘豚鼠BALF及肺组织嗜酸粒细胞数量，与其抑制eotaxinmRNA在哮喘豚鼠肺组织的表达有关。

Conclusions Mycobacterium vaccine can decrease the number of eosinophils in BALF and lung tissues , which can inhibit the expression of Eotaxin mRNA in lung tissues of asthmatic guinea pig .

结论血清ECP水平能更准确反映哮喘患儿嗜酸粒细胞活化状态和气道炎症变化，是诊断、判断病情及指导治疗的可靠指标。

Conclusion These results suggest that the level of serum ECP can reflect the inflammation in the bronchial tube and the activated state of eosinocyte more sensitively than IgE .

结果：应用cpGODN组与对照组相比：（1）明显抑制抗原激发后气道内嗜酸粒细胞的浸润（P<0.01）；

Results : ( 1 ) Compared with the control , coadministration of CpG ODN in sensitization phase significantly inhibited airway eosinophilia after antigen challenge ( P < 0.01 ) .

进一步采用细胞培养、实时定量RTPCR和原位ELISA技术研究TGFβ1及嗜酸粒细胞对人呼吸道上皮细胞系BEAS2B细胞TNC表达的调控作用。

The cell culture , real-time RT-PCR and in situ ELISA techniques were employed to investigate the effect of TGF - β 1 and eosinophils on the TNC mRNA and protein expression in BEAS-2B immortalized human bronchial epithelial cells .

目的探讨Slingshot-1L（SSH-1L）在哮喘病人外周血嗜酸粒细胞（EOS）的表达及其功能。

Objective To investigate the expression of Slingshot-1L ( SSH-1L ) in peripheral blood eosinophils of asthmatic patients .

目的探讨外周血CD34+细胞、白细胞介素-5（IL-5）和嗜酸粒细胞（EOS）在支气管哮喘发病中的作用。

Objective To study the significance of CD34 + cell , interleukin-5 ( IL-5 ) and eosinophil ( EOS ) in the peripheral blood of the asthma patients in diagnosis and treatment .

观察用药前后症状积分、β2受体激动剂用量、末梢血嗜酸粒细胞（Eos）分类计数、血清IgE、肺功能、尿白三烯E4（uLTE4）的变化。

Asthmatic symptom score , usage of β _2 receptor agonist , percentage of eosinophil , serumal IgE concentration , spirometry and urinary leukotriene E_4 ( uLTE_4 ) were measured pre - and post-treatment .