外毛细胞

结论：卡铂损害耳蜗传出神经系统可能是由于外毛细胞受损所致。

Conclusion : These results suggest that carboplatin damaged efferent sytems may be due to the damage of OHC .

结果正常对照组A组的耳蜗内、外毛细胞在离体培养48小时后，其平均存活率分别为97.0%±4.0%和98.7%±2.7%；

Results The survival rate of IHC and OHC of normal medium , group A , is 97.0 % ± 4.0 % and 98.7 % ± 2.7 % ;

结果耳聋肾虚组与耳聋非肾虚组外毛细胞的每视野数比较，差异无显著性（P＞0.05）；

Results Inter-group comparison showed no significant difference in the number of outer hair cells ( P > 0.05 );

B组耳蜗外毛细胞的损伤明显较C组重。

The damage of outer hair cells of group B was much more severely hurt than that of group C.

在外毛细胞区偶可见TH阳性的终末；

The TH positive endings could be seen in the OHC region .

暴露于庆大霉素的B组耳蜗内、外毛细胞平均存活率分别为4.3%±5.1%和4.1%±1.8%；

The survival rate of IHC and OHC of group B is 4.3 % ± 5.1 % and 4.1 % ± 1.8 % ;

过氧化氢和维生素E对老年豚鼠耳蜗外毛细胞大电导钙激活钾通道作用的实验研究

Effect of Hydrogen Peroxide and α - tocopherol on High-conductance Calcium-activated Potassium Channels of Outer Hair Cells of Cochlea in Guinea Pigs

B组小鼠ABR阈值变化明显小于A组（P<0.01），外毛细胞的损害也明显减轻；

Mice in group B significantly attenuated ABR threshold shifts with out hair cells loss ( P < 0.01 ) .

E组与A组之间无显著性差异，但E组内、外毛细胞的存活率又明显高于C、D两组（P<0.01）。

Group E and A have no difference , but E is higher than C and D , the difference between them was statistically significant ( P < 0.01 ) .

GM＋DMSO组外毛细胞受损程度较GM组明显为轻。

The structural damage of outer hair cells was severer in the GM group than that in the GM plus DMSO group .

川芎嗪开放外毛细胞钾通道的细胞内PKA机制

The PKA mechanism of the increasing K ~ + currents of outer hair cells by TMP

KM用药一周即可豚鼠耳蜗内、外毛细胞的损伤。

KM ( 400mg / kg / d ) can impair both outer and inner hair cells in guinea pig 's cochlea , by im , after 7 days .

结果①A组小鼠ABR阈值明显提高（P<0.01）并伴随外毛细胞的减少；

Results Mice in group A developed significant ABR threshold shifts ( P < 0.01 ), which were accompanied by out hair cells loss .

耳蜗各回内外毛细胞均呈NOS阳性反应，内毛细胞区较外毛细胞区染色深；

Both internal and external hairy cells of cochlear nucleus show NOS positive reaction . The stain of internal hairy cells were darker than that of the external .

结果：注射卡铂后从24h～3个月，灰鼠的外毛细胞基本无缺损。

Result : Loss of outer hair cells was not observed on basal membrane from 24 hours to 3 months after drug administration except one ear .

ATP和乙酰胆碱诱发豚鼠耳蜗外毛细胞内CICR的激光共聚焦研究

ATP and ACh induced CICR in outer hair cells of the guinea pig cochlea : study of confocal microscopy

B组：L-乙酰半胱氨酸（NAC）的外毛细胞平均损伤率为65%，内毛细胞平均损伤率为60%。

The mean outer hair cell ( OHC ) loss rate was 65 % in group B , and its mean inner hair cell ( IHC ) loss rate was 60 % .

结果：采用这种方法培养的外毛细胞，在存活的20h内，其细胞形态和结构无明显改变。

Results : The structure and morphology of outer hair cells remained unchanged during 20 hours .

强次声波对豚鼠Corti器外毛细胞脱氢酶活性的影响

Effects of intense infrasound on activities of dehydrogenase of the organ of Corti in guinea pigs

一根GABA-IR阳性的神经纤维，在外毛细胞区可形成6～7个终末。

One GABA-IR positive nerve fiber could form synapse with 6-7 OHCs .

目的研究外毛细胞运动产生畸变产物耳声发射（DPOAE）的机理。

Objective To study the mechanism of the production of distortion product otoacoustic emissions ( DPOAE ) by electromobility of out hair cell .

结果：CGRP阳性反应物分布于螺旋神经元，骨螺旋板神经孔，内毛细胞、外毛细胞与外支持细胞交界区，螺旋韧带血管纹。

Result : CGRP immunoreactivity was located in SGN , nerve fibers at osseous spiral lamina , stria vascularis , IHC , adjacent area of OHC and Deiters ' cells .

目的：探讨豚鼠耳蜗外毛细胞（OHC）和Deiters细胞（DC）同时分离的方法。

Objective : To investigate the simultaneous method of isolating outer hair cells and Deiters ' cells from the organ of Corti of the guinea pig cochlea .

豚鼠耳蜗外毛细胞和Deiters细胞的同时分离法

The simultaneous isolation of outer hair cells and Deiters ' cells from the cochlea of the guinea pig

豚鼠耳蜗单离外毛细胞和Deiters细胞的钾离子电流及其生理功能

Potassium Currents and Their Possible Functions in Isolated Outer Hair Cells and Deiters ′ Cells of Guinea Pig Cochlea

结果爆炸冲击波和实验性冲击波负压暴露后8～24h即可见基底膜外毛细胞大部分缺失。

Results Most of the outer hair cells were lost and lacerating injury was seen in the basilar membrane of guinea pigs in 8-24 h after exposure to explosive blast waves and experimental blast underpressure .

结论：（1）噪声性听损伤的ABR变化反映了声损伤始于外毛细胞，逐渐累及内毛细胞、听神经和脑干听觉通路的病变过程。

Conclusions ( 1 ) The ABR results of noise-induced hearing loss are correlated with a gradual pathological process from outer to inner hair cells , then to auditory nerve and brainstem auditory pathway .

照射后15～30d，外毛细胞纤毛除具有照射后早期变化外，还出现外毛细胞纤毛重组，以及内毛细胞边缘球形物隆起。

From 15 to 30d after radiation , reconstruction of cilia besides early changes , and ball shape materials on the side of inner hair cells were found .

镫骨全切除后，听泡内较长时间地（60min）应用吸引器可引起CAP明显阈移和耳蜗底回部分外毛细胞的不可逆病变；

Significant CAP threshold shift and irreversible pathological changes in some outer hair cells in the basal turn of cochlea were found with continuous suction for 60 minutes in auditory bulla after total stapedectomy .

免疫电镜发现在外毛细胞底部有GABA-IR阳性的传出神经末梢及阴性的传入、传出神经末梢。

Under TEM , GABA-IR positive efferent endings , negative efferent endings and negative afferent endings could be seen on the OHC bases .