寡霉素

大鼠寡霉素敏感相关蛋白（OSCP）基因在大肠杆菌中的克隆和表达

The Cloning and Expression of Oligomycin Sensitivity - Conferring Protein ( OSCP ) Gene in E.coli

肝亚线粒体H＋转运ATP酶活性及其对寡霉素的敏感性虽低于对照组，但较正常饲料冷暴露组均明显升高，膜的流动性也明显升高（P＜0.05）。

The membrane fluidity , the activity of H + transporting ATPase and its sensitivity to oligomycin in group 3 were significantly greater than those of the group 2 . The findings indicated that supplement with zinc might increase the level of zinc in cold-exposed rats .

目的获取具有正确核苷酸序列的大鼠寡霉素敏感相关蛋白（OSCP）基因。

Objective To obtain the correct nucleotide sequence of oligomycin sensitivity - conferring protein ( OSCP ) of rats .

目的通过将发生点突变的两个大鼠寡霉素敏感相关蛋白（OSCP）基因进行改造，获得具有正确序列的OSCP基因，在大肠杆菌中表达并进行活性鉴定。

Objective To obtain a corrected sequence of rat oligomycin sensitivity-conferring protein ( OSCP ) gene by modifying the two mutated rat OSCP genes which have point mutation , then express the OSCP gene in E.

目的构建大鼠寡霉素敏感相关蛋白（OSCP）基因重组质粒。

Objective To construct a recombinant plasmid containing oligomycin sensitivity conferring protein ( OSCP ) gene of rat . Methods Total RNA was extracted from the rat brain tissue and used as templates for RT PCR .

另外，寡霉素具有体外逆转人白血病多药耐药细胞株K562／A02对ADM耐药性的作用，可能与抑制P-gp的活性增加细胞对化疗药物的摄取率有关，而与P-gp表达量的下降无关。

Moreover , oligomycin can reverse the multidrug resistance of human leukemic K562 / A02 cells to ADM in vitro , the possible mechanism is related to the inhibition activity of P-gp and increased accumulation of the chemotherapeutic agents in cells , while the expression of P-gp is not down-regulated .

寡霉素在叶绿体中的作用部位

Study on the Action Site of Oligomycin in Chloroplast

寡霉素对叶绿体质子传导的作用

Effects of oligomycin on proton conduction in chloroplasts

冷暴露大鼠心肌线粒体内膜流动性及寡霉素敏感蛋白变化

Changes of Intimal Fluidity and Function of the Oligomycin Sensitive Protein of Myocardial Mitochondria in Rats During Cold Exposure