施万

NT3基因修饰施万细胞促进移植的神经干细胞在损伤脊髓内分化为神经元样细胞

NT-3 genetically modified Schwann cells promote grafted neural stem cells differentiate into neuron-like cells in the injured spinal cord

NT-3基因修饰施万细胞促进神经干细胞体外分化为神经元样细胞

NT-3 genetically modified Schwann cells promote neural stem cells to differentiate into neuron-like cells

本试验通过对SD大鼠腹股沟脂肪的提取和培养，获得脂肪干细胞，并在体外诱导其分化成施万细胞。

In this experiment , ADSCs were derived from groin adipose tissue of SD rats . They were cultured and developed into Schwann cells in vitro .

【目的】构建神经营养素-3（NT-3）基因转染的施万细胞。

To construct neurotrophin 3 ( NT 3 ) genetically modified Schwann cells ( SCs ) .

ADSCs在体外可以被诱导分化成类施万细胞，并表达其特异性标志物。

Schwann-like cells can be induced from ADSCs in vitro , expressing Schwann specific biological markers . 3 .

施万细胞移植后8个月仍可见BrdU阳性细胞并主要向大脑皮质迁移；

BrdU positive cell could be seen even at 8 months after SC transplantation , which mainly migrated towards cerebral cortex .

结果扩张段及狭窄段结肠壁S-100在神经丛内的神经纤维、施万细胞及周围细胞均有阳性表达，而在神经节细胞则无阳性表达；

Results Nerve fiber , schwann cell and peripheral cell of expanding segment were S-100 positive , but neurons were S-100 negative , nNOS positive ;

目的研究重组睫状神经营养因子（CNTF）对受损周围神经施万细胞基因表达的作用。

Objective To study effects of recombinant ciliary neurotrophic factor ( CNTF ) on gene expression of Schwann cells in the injured peripheral nerves .

高葡萄糖对施万细胞CGT和GalC表达的影响

Expressions of CGT and GalC in Schwann Cells Cultured in High Glucose

【方法】NT-3基因重组腺病毒（AdvNT-3）扩增、纯化和测定后，转染体外培养的施万细胞（SCs）。

The NT 3 gene recombinant adenovirus ( AdvNT 3 ) were amplified , purified , and determined . Then , it was used to genetically modify SCs .

目的观测神经营养素-3（NT-3）基因修饰施万细胞（SCs）对神经干细胞体外分化为神经元样细胞的影响。

AIM : To explore the effects of neurotrophin-3 ( NT-3 ) - genetically modified Schwann cells ( NT-3-SCs ) on differentiation of neural stem cells ( NSCs ) into the neuron-like cells .

目的探讨移植的施万细胞对大鼠脊髓半横切后背核神经元存活及其表达NOS的影响。

Objective The effects of implanted Schwann cells ( SCs ) on the neuronal survival and expression of nitric oxide synthase ( NOS ) in Clarke 's nucleus ( CN ) following spinal cord hemisection ( SCH ) in rat were explored .

目的研究大鼠沃勒变性段面神经施万细胞（SchwanncellsfromWalleriandegeneratingfacialnerve，WFSC）分离纯化、培养方法，观察其形态表型和一般生物学特性。

Objective To investigate techniques among isolation , purification , proliferation of Schwann cells derived from Wallerian degenerating facial nerve ( WFSC ) in rats and to study the characteristics in morphological phenotype and growth in vitro .

施万细胞对丙烯酰胺致背根神经节感觉神经细胞损伤的保护作用

Effect of schwann cells on cultured sensory neurons damaged by acrylamide

施万细胞高效体外传代培养的实验研究

Experimental Study on Efficient Serial Subcultivation of Schwann Cells in Vitro

单纯电针损伤组和施万细胞移植组新生的髓鞘。

Neogenetic myelin sheath in both control group and SC group .

自体施万细胞神经膜管移植修复大鼠脊髓损伤的实验研究

Repairing of Spinal Cord Injury with Schwann Cell Neurilemma Channel in Rats

大鼠脂肪源性干细胞定向分化为施万细胞样细胞的实验研究

Induced differentiation of rat adipose-derived stem cells into Schwann-like cells

硫脂致敏豚鼠血清诱导体外培养的施万细胞凋亡及其机制

Antisera of guinea pigs against sulfatide induce apoptosis in cultured Schwann cells

大鼠脑出血移植施万细胞的实验研究

Experimental Study of Schwann Cells Transplanted into Cerebral Hemorrhage Area of Rats

坐骨神经再生过程中施万细胞自噬的形态学观察

Morphological observation of Schwann cell autophagy during regenerative course of sciatic nerve

轴突影响施万细胞分化与整合素α6β4表达

Axonal regulation of Schwann cell differentiation and integrin α _6 β _4 expression

大鼠沃勒变性面神经施万细胞纯化培养实验研究

Purification of cultured Schwann cells derived from Wallerian degenerating facial nerves in rats

施万细胞在蚕丝支架上三维培养的体外活性研究

Study of activity of Schwann cells cultured three-dimensionally on silk scaffold in vitro

施万细胞的功能及其在视神经保护中的应用

The Function of Schwann Cells and Its Application in the Optic Nerve Protection

施万细胞仍是最常使用的种子细胞，但干细胞已开始被用作种子细胞。

Besides Schwann cells , stem cells have been used as seed cells .

腺病毒介导神经营养素-3基因转染施万细胞

Transfection of Adenovirus-mediated Neurotrophin-3 Gene into Schwann Cells

施万细胞对培养的神经干细胞存活及其分化的影响

Effects of Schwann cells on survival and differentiation of neural stem cells in vitro

施万细胞在周围神经系统轴突损伤修复中起着至关重要的作用。

Schwann cells play an important role in axonal regeneration from peripheral nervous injuries .

自噬在大鼠坐骨神经横切后施万细胞去分化中的作用

Role of Autophagy in Dedifferentiation of Schwann Cells after Transection of Rat Sciatic Nerve