染色体缺失

目的：探讨乳癌组织中第10号染色体缺失的磷酸酶和张力蛋白同源物基因（PTEN）的表达及其意义。

Aim : To investigate the expression of PTEN and its clinical significance in breast carcinoma tissue .

Prader-Willi综合征亲源染色体缺失和母源单亲二体染色体之间行为表型的差异：一项事件相关脑活动（ERP）研究

Differences in behavioural phenotype between parental deletion and maternal uniparental disomy in Prader-Willi syndrome : An ERP study

本研究的目的是观察伴有5号染色体缺失的MDS细胞株MUTZ-1细胞的遗传学变化。

This study was aimed to investigate the cytogenetic changes of MDS cell line ( MUTZ-1 ) with chromosome 5q deletion .

结果表明：50例PV患者中CC检出3例核型异常，1例为8三体，1例为Y染色体缺失，1例为11号染色体倒位。

The results showed that out of 50 cases , the 3 cases had chromosome karyotype abnormality , including trisomy 8 , deletion of chromosome Y and inversion of chromosome 11 by CC technique .

荧光原位杂交技术检测多发性骨髓瘤13号染色体缺失

Detecting chromosome 13 deletion in multiple myeloma with fluorescence in situ hybridization

138例慢性髓系白血病衍生9号染色体缺失的研究

Deletions of Derivative Chromosome 9 in 138 Patients with Chronic Myeloid Leukemia

遗传背景对小麦染色体缺失效应的研究

Effects of Different Wheat Genetic Backgrounds on Chromosome Deficiency

17例多发性骨髓瘤患者13号染色体缺失的检测

To Identify the Deletion of Chromosome 13 in 17 Patients with Multiple Myeloma

第10号染色体缺失的磷酸酶和张力蛋白在谷氨酸诱导海马神经元损伤中的作用研究

Effects of the Phosphatase and Tensin Homologue Deleted on Chromosome 10 on Hippocampus Neurons Injury Caused by Glutamate

其二是由于轮回选择的超多次杂交，使减数分裂受到更多干扰，形成较多的染色体缺失、重复和倒位等染色体畸变，从而出现新的性状。

The second is that in the recurrent selection extra-crossing interferes the meiosis and causes more chromosome deficiency , duplication and inversion , all of these chromosomal aberrations produce new phenotypes .

X染色体部分缺失与性腺发育不全

Gonadal dysgenesis with deletion of the X chromosome : a report of 3 cases

无精症患者Y染色体微缺失的多重PCR筛查

Multiplex PCR for screening of microdeletions on the Y chromosome in azoospermic patients

目的探讨多重PCR法检测Y染色体微缺失对男性不育患者的病因学诊断价值。

Objective To study the diagnosis value on Y chromosmal microdeletions with gene chip technique in male infertility .

方法采用多重PCR技术，对63例原发性无精子症患者和20例正常已生育男性对照进行Y染色体微缺失的检测。

Methods : Multiplex PCR was used to detect Y chromosome microdeletion in 63 azoospermia patients and 20 healthy controls .

多条染色体的缺失更多见于混合细胞型和上皮样细胞型（P0.05）。

( P0.05 ) Multiple loss of chromosome was more frequent in mixed cell type and epithelioid cell type .

Klinefelter综合征Y染色体微缺失的检测

Detection of Y chromosome microdeletions in azoospermic patients with Klinefelter ′ s syndrome

后者均系不平衡易位所致，其中不少被CC误认为染色体部分缺失、不明来源的额外物质、染色体单体和标记染色体等。

The derivative chromosomes resulted from unbalanced translocations , most of which were missed as chromosome deletion , additional material of unknown origin , monosomy and marker chromosome .

【目的】建立一套Y染色体微缺失的多重PCR筛查方法，对因无精症或少精症欲行单精子卵细胞浆注射（ICSI）治疗的男性不育患者进行Y染色体微缺失的常规筛查。

To develop a multiplex PCR protocol , suitable for routine screening of microdeletions on the Y chromosome in male infertility patients undergoing intracytoplasmic sperm injection ( ICSI ) .

继发于裂隙染色体9q缺失的痣样基底细胞癌综合征

NBCCS secondary to an interstitial chromosome 9q deletion

目的探讨具有磷酸酶活性的抑制基因&与张力蛋白同源的在10号染色体有缺失的磷酸酯酶（phosphataseandtensinhomologdeletedonchromosome10，PTEN）在兔晶状体上皮细胞增殖中的作用。

Objective To discuss the effects of ( phosphatase and tensin homolog deleted on chromosome 10 ) PTEN on the proliferation of lens epithelial cells ( LECs ) in rabbits .

目的已报道人类染色体8p缺失可能与肝癌转移有关，本文应用实时定量聚合酶链反应（RQ-PCR）研究位于8p的DLC-1基因mRNA表达与肝细胞癌侵袭转移的关系。

Objective To study the relationship between the expression level of DLC-1 mRNA ( located in 8p ) and the invasion / metastasis of human hepatocellular carcinoma ( HCC ) .

目的亚克隆野生型与张力蛋白在10号染色体同源缺失的磷酸酶（PTEN）基因，构建四环素反应性元件调控的与张力蛋白在10号染色体同源缺失的磷酸酶反应质粒（pTREPTEN）。

Objective To subclone human cDNA of gene of phosphatase and tensin homology deleted on chromosome ten ( PTEN ) and construct plasmids of tetracycline ( Tet ) responsive element , which regulates and controls the expression of PTEN ( pTRE PTEN ) .

Y染色体微缺失与男性不育的关系探讨

A Research on Relation Between Y Chromosome Microdeletions and Male Infertility

10号染色体上缺失的磷酸酶与张力蛋白同源物基因与神经发育

Phosphatase and Tensin Homology Deleted on Chromosome 10 and Neural Development

Y染色体微缺失与无精子症少精子症关系的研究

Study on relationship of Y chromosome microdeletion with azoospermia or oligozoospermia

促性腺激素治疗Y染色体微量缺失的无精子症患者1例

Gonadotropin treatment of an azoospermic patient with a Y-chromosome microdeletion

无精、严重少精症患者细胞遗传学和Y染色体微缺失研究

Cytogenetic and Y Chromosome Microdeletions in Patients with Azoospermia and Severe Oligozoospermia

人类Y染色体微缺失与精子生成障碍的研究进展

Advance in the Research of the Human Y Chromosome Microdeletion and Spermatogenic Failure

单体7或7号染色体长臂缺失的意义

Significance of Monosome 7 or Deletion of the Long Arm of Chromosome 7

Y染色体微缺失父子间垂直遗传分析

Study on the vertical transmission of Y chromosome microdeletions from father to son