棘细胞层

建筑的表皮LC主要位于表皮棘细胞层和毛囊根鞘；

In the skin LC were located mainly in the stratum spinosum of the epidermis .

与之相反，p53阳性反应主要在棘细胞层下部和基底细胞层。

Maximum expression of p53 existed in the lower and basal layers of epidermis .

ICAM1、HLADR以及β1整合素在表皮基底细胞层和棘细胞层诱导表达或增强表达。

The expression of ICAM 1 and HLA DR was induced on basal keratinocytes , epidermal dendritic cells as well as endothelial cells in the dermis .

结果可见：PCNA在不同的组织中分布及表达不同，随着病变程度的增加，PCNA分布由基底细胞层逐渐累及到棘细胞层，各组间PCNA阳性细胞百分数有显著性差异。

The results showed that PCNA was not alike about distribution and expression in different group . There were statistical differences in different groups .

结果在正常皮肤组织中，Caspase-3的表达仅局限于表皮基底细胞层的细胞浆，在银屑病皮损中，Caspase-3表达弥散分布于增生表皮的基底细胞层、棘细胞层及颗粒细胞层；

Results Immunohistochemical examination showed that the expression of Caspase-3 was positive only in basal layers of normal epidermis and positive in the suprabasal cell layers of psoriatic epidermis .

结果IGFIR蛋白与mRNA表达在银屑病患者基底层和棘细胞层，IGFIR蛋白与mRNA相对积分光密度值在正常对照组与银屑病组间存在极显著性差异（P＜0.01）。

Results The expressions of IGF IR protein and mRNA were located on the basal cell layers and prickle cell layers . There was significant difference of mRNA expression between the normal and psoriatic groups ( P < 0.01 ) .

在OLP组中，LC位于棘细胞层的中、下部及基底细胞层，有的标本中LC可见于棘细胞全层，固有层中多见。

Whereas in OLP , they mainly located in the middle and lower regions of the prickle cell layer and the basal cell layer , but throughout the prickle cell layer in some .

正常宫颈上皮未见明显着色；CIN组阳性表达见于基底层和棘细胞层，着色较深；宫颈癌组主要在癌巢周边表达，着色深，血管及腺体周围也有表达。

Normal cervical epithelium was negative staining ; CIN group was weak staining in basal layer and / or prickle cell layer ; In cervical carcinoma group , the positive granulas were strongly staining around cancer nests , blood vessels and glands .

结果电镜下银屑病表皮颗粒层中细胞凋亡并不常见，在棘细胞层与基底层则更少，但TUNEL染色见阳性细胞广泛分布于表皮各层。

Results The electron microscopic findings revealed that apoptosis is not a common phenomenon in the granular layer and even more rare in the basal and spinous layers of psoriatic skin , while TUNEL staining showed numerous positive cells in all layers of psoriatic epidermis .

结果IL8免疫反应主要定位于表皮的基层、棘细胞层和颗粒层、血管内皮细胞及间质细胞；

Results IL 8 was mainly localized at the basal cell layer , spinous cell layer and granular cell layer of the epidermis , the endothelium of the blood vessels and interstitial cells ;

阳性细胞主要分布于棘细胞层。

The positive cells mainly distributed in spinous layers , especially in koilacytes .

阳性信号主要位于表皮棘细胞层，尤以挖空细胞和异型核细胞著明。

The positive singals mainly located in the spinous cells of epidermis , markedly positive in the nuclei of koilocytes and anaplastic cell .

本型组织病理改变，主要是表皮角质层有显著角化不全，棘细胞层增厚，表皮突向下延展，深入真皮。

Pathological changes of the organization , mainly the epidermal cuticle significant parakeratosis , acanthosis cell layer thickening , epidermal sudden downward extension of in-depth dermis .

后期表皮棘细胞层明显增生呈假乳头状瘤样，基底细胞液化明显。

In the late stage , there revealed obvious proliferation of epithelial prickle cell layer in shape of pseudopapillomatous mass with the obvious liquefaction of basal cells .

培养过程中表皮逐步增殖、分化、发育，形成基底层、棘细胞层、颗粒层和角质层；

Epidemis of the skin consisted of Kc at various proliferation and differentiation stages , which proliferated and differentiated into basal cell layer , prickle cell layer , granular layer , and cornified layer .

结果：在18例光暴露皮肤中P53表达均为阳性，阳性表达位于基底细胞及棘细胞全层，呈散在分布。

Results : The expression of protein P53 was positive in all the 18 specimens , and the stain was distributed in basal cells and prick cells .

101例扁平苔藓中36例表达Cox-2，阳性率为35.6%，病变表现为上皮棘层细胞、粒层细胞和表层细胞呈阳性表达，基底细胞呈阴性表达。

Cox-2 was expressed in 36 cases out of 101 cases of OLP , the positive ratio was 35.6 % , which both pathological changes showed Cox-2 over-expressed in the cytoplasm of stratum spinosum cells and stratum granulosum cells , basal cells submitted negative expression .