氨肽酶

氨肽酶N在胆固醇结石成因中作用的初步研究

Preliminary study on effect of aminopeptidase N on etiology of cholesterol gallstones

胆汁中氨肽酶N的分离、提纯及其促成核作用的初步研究

Isolation and purification of aminopeptidase N and promotion of nucleating activity in bile

人氨肽酶N基因克隆和原核表达

Molecular cloning and prokaryotic expression of human aminopeptidase N

1，2-二氨基-3-苯丙烷类氨肽酶N抑制剂的设计、合成及其活性研究

Design , Synthesis and Activity Study of 3-Phenylpropane-1,2-Diamine Derivates as Aminopeptidase N Inhibitors

氨肽酶NmRNA在雏鸡不同组织中的表达情况

Expression of aminopeptidase N mRNA in different tissues of chicks

鸡氨肽酶H在大肠杆菌中的表达、纯化与部分酶学性质分析

Expression in Escherichia coli , Purification and Enzymatic Properties of Chicken Aminopeptidase H

氨肽酶产生菌~（60）Coγ射线诱变育种的研究

Study on mutation breeding of aminopeptidase-producing strain by ~ ( 60 ) Co γ rays

十二指肠大豆小肽梯度灌注对山羊乳腺氨基酸吸收与氨肽酶N基因表达的影响

Effect of Duodenal Soybean Small Peptides Infusion on Mammary Uptake of Amino Acid and Expression of APN in Lactating Goat

昆虫中肠Bt杀虫晶体蛋白毒素受体氨肽酶N的研究进展

Progress of studies on insect midgut aminopeptidase N serving as Bacillus thuringiensis insecticidal crystal protein toxin receptor

抗Bt棉棉铃虫幼虫Bt受体氨肽酶N（APN2）基因克隆

Molecular Cloning of Bt Toxin Receptor Aminopeptidase N From Larvae of Helicoverpa armigera H ü bner Resistant to Bacillus thuringiensis

其底物专一性、很小的Mr等理化特性均表明它是Bowman&Birk抑制家族的一员。该抑制剂的作用靶酶是胰蛋白酶，对亮氨酸氨肽酶活性有轻微影响。

The inhibitor is a member of Bowman & Birk family because of the specificity for its substrate , the much lower Mr and other physical and biochemical features .

氨肽酶是一类从多肽链的N端顺序水解氨基酸、使氨基酸逐个游离出来的酶，主要应用于食品工业。

Aminopeptidase is a kind of hydrolytic enzymes , freeing the amino acids from the N-ter-minal sequence of the proteins or peptides , mainly used in the food industry .

靶标昆虫中Bt受体蛋白主要有两类：氨肽酶和类钙粘蛋白。

There are two kinds of receptor proteins of Bt toxic protein in insect body , aminopeptidase receptors and cadherin-like receptors .

氨肽酶N（APN）属于金属蛋白酶家族，在肿瘤的侵袭和血管生成方面，发挥着重要的作用，其发挥作用需要锌离子的参与。

AminopeptidaseN ( APN ) belongs to a family of zinc-dependent metalloproteinase that plays an essential role in tumor invasion and angiogenesis .

氨肽酶抑制剂Bestatin通过激活半胱天冬酶3诱导HL-60细胞凋亡

Aminopeptidase inhibitor Bestatin induces HL-60 cell apoptosis through activating caspase 3

为研究大鼠高胆固醇饮食时，肝脏氨肽酶N（APN）在实验结石形成中可能的结石发生作用，采用1.2%胆固醇饮食4周，诱发新西兰兔胆囊结石形成。

The aim was to explore the possible lithogenic role of aminopeptidase N ( APN ) in experimental gallstone formation in rabbits with high cholesterol diet .

棉铃虫Bt毒素受体蛋白&氨肽酶N1基因克隆及其在昆虫细胞系的表达

Gene Cloning of Aminopeptidase N1-Receptor for Bt Toxin in Helicoverpa Armigera ( H ü bner ) and Its Expression in Tn Cells

目的研究半胱天冬酶3在国产氨肽酶N抑制剂Bestatin（商品名百士欣，BS）诱导人白血病细胞凋亡过程中的变化及其意义。

Objective To study the variation and significance of caspase 3 activity in the process of amino peptidase inhibitor & bestatin ( BS ) inducing human leukemic cell apoptosis .

由氨基酸组成求得最小分子量约16500。（4）用二硝基氟苯，二甲基氨基萘磺酰氯及氨肽酶M测定抑制剂A、B的N末端，都证实是天冬氨酸。

The minimum molecular weights as estimated from the amino acid compositions were about 16,500 . For both inhibitors A and B the N-terminal amino acid was aspartic acid , as determined by the FDNB and DNS-Gl methods and further confirmed by enzymic hydrolysis with aminopeptidase M.

目的从胆石症病人胆汁中分离、提纯氨肽酶N（AminopeptidaseN，APN），观察其成核活性，并探讨熊去氧胆酸对APN的影响。

Objective [ WT5BZ ] Aminopeptidase N ( APN ) was purified from the bile of patients with gallstones and its nucleation effect was studied in order to evaluate the effect of ursodeoxycholic acid ( UDCA ) on APN .

目的观察胆固醇结石病人和无结石者之间胆囊胆汁中氨肽酶N（APN）活性的变化及熊去氧胆酸（UDCA）对APN活性的影响。

Objective To observe the difference of aminopeptidase N ( APN ) activity in gallbladder bile between patients with cholesterol gallstones and those without them and the effect of ursodeoxycholic acid ( UDCA ) on APN activity .

氨肽酶抑制剂&Bestatin诱导人白血病细胞凋亡的研究

The aminopeptidase inhibitor & bestatin induces apoptosis in human leukemic cells

尿丙氨酸氨肽酶在糖尿病肾病早期诊断中的临床观察

The usefulness of AAP in the early diagnosis of diabetic nephropathy

几种氨肽酶把肽水解成氨基酸。氨基酸可以被氧化脱氨基作用分解。

Several aminopeptidases complete the hydrolysis of peptides into amino acids .

一种枯草芽孢杆菌氨肽酶的纯化及酶学性质

Purification and Characteristic of a Kind of Aminopeptidase from Bacillus subtilis

水稻叶片衰老过程中氨肽酶活性的变化

Changes of aminopeptidase activity during leaf senescence in Rice

母体血浆胎盘亮氨酸氨肽酶和白介素-6与自发性早产的关系

Correlation of maternal plasma placental leucine aminopepticlase and interleukin-6 with spontaneous preterm labor

N~+注入诱变选育氨肽酶高产菌株及发酵条件初步优化

Breeding of Aminopeptidase-producing Strains by N ~ + Implantation and Preliminary Research on Fermentation Conditions

非小细胞肺癌氨肽酶N/CD13的表达及临床意义

Expression of Aminopeptidase N / CD13 and Its Clinical Significance in Non-small Cell Lung Cancer

枯草芽孢杆菌氨肽酶的研究

Studies on Bacillus Subtilis Aminopeptidase