甲基组氨酸

HPLC法测定人尿液中的3-甲基组氨酸

Determination of human urinary 3-methylhistidine by HPLC

目的采用HPLC法测定人尿液中3-甲基组氨酸（3-MH）的含量。

AIM To develop a HPLC method to determine the concentration of 3-methylhistidine in human urine .

家系成员中高血压组与正常血压组血液代谢产物比较，柠檬酸、肌醇、1-甲基组氨酸及酪氨酸含量均降低，且有统计学意义（P0.05）。

Citrate , phaseomannite , 1-methyl histidine and tyrosine levels were all decreased significantly ( P0.05 ), When comparing serum metabolites between hypertension group and normal blood pressure group in Uyghur MODY family members .

尿3-甲基组氨酸的排出对照组大于研究组（7.3士1.0比4.4士0.3μmol／（kg·d），P＜0.05）。

Excretion of urinary 3-methylhistidine in control group loss more than in GH group ( 7 . 3 ± 1.0 μ mol / ( kg · 24h ) vs 4 . 4 ± 0 . 3 μ mol / ( kg · 24h ), P < 0.05 ) .

分别于伤后2h和6h，采用高效液相-荧光法检测胸大肌、肋间肌和膈肌内三甲基组氨酸（3-MH）的含量，Northern杂交检测泛素、蛋白酶体C2亚基mRNA表达的变化。

Two and six hours post-injury , contents of 3-methylhistidine in pectoralis major muscle , intercostal muscle and diaphragmatic muscle were determined with high performance liquid chromatography . The expressions of ubiquitin mRNA and C_2 subunit mRNA in those muscles were assessed with Northern blot analysis .

力量练习对血清肌酸激酶、肌红蛋白和尿3&甲基组氨酸水平的影响

Effect of weight training on serum CK MB and urinary 3-methylhistidine levels

产后奶牛血、尿中羟脯氨酸、3-甲基组氨酸和3-MEHIS浓度的研究

Blood and urinary concentrations of hydroxyproline and 3-methyl histidine in postpartum cow

尿钙、镁、牛磺酸、1－甲基组氨酸等变量均降低。

Urinary potassium , calcium , magnesium , taurine and 1-mhis were low .

本文研究8例烧伤总面积60.3±19.7%男性成年病人，用~（15）N-甘氨酸示踪技术测定总体蛋白质代谢速度，用尿3-甲基组氨酸排出量估计肌肉蛋白质分解速度。

Eight male adults with burn area 60 ± 20 % BSA were studied . ~ ( 15 ) N-glycine tracing technique was used to determine total body protein kinetics , and urinary 3-methylhistidine ( 3MH ) excretion was measured to evaluate muscle protein catabolism .