癌蛋白
- 名Oncoprotein;cancer protein
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目的研究cMyc癌蛋白在食管鳞癌中的表达及其意义。
Objective To study the importance of the expression of c myc cancer protein in esophageal squamous cell carcinoma .
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结论cMyc癌蛋白表达与食管鳞癌的生物学行为有一定相关性。
Conclusion The expression of c myc cancer protein was related to the biological behavior of esophageal squamous cell carcinoma .
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内源性血管生成抑制剂可作为一种抑癌蛋白。
Endogenous angiogenesis inhibitors act as tumor suppressor proteins .
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Bcl-2癌蛋白在急性髓性白血病的表达
Bcl 2 protein expression in acute myeloid leukemia
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肾癌组织中P53和C-myc癌蛋白的表达评价
Expression of C-myc and P53 in human renal cancer
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P物质对大鼠下丘脑催产素及加压素免疫反应性神经元Fos癌蛋白的诱导作用
Induction of Fos oncoprotein expression oxytocin or vasopressin containing neurons in the hypothalamus by substance P in the rat
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[方法]应用免疫组化和同位素点杂交技术对新鲜冰冻甲状腺组织HER2/neu癌蛋白和mRNA的表达进行研究。
HER 2 / neu oncoprotein and mRNA were detected in frozen thyroid tissue specimens by immunohistochemistry and isotope Dot blot hybridization .
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抑癌蛋白p21和p53表达与胃癌细胞增殖的关系
Relationship between expression of tumor supressor protein p21 and p53 and cell proliferation in the gastric carcinoma
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rasp21癌蛋白在颊粘膜上皮癌前及癌变中表达的定量分析
Quantitative analysis of the expression of p21 in premalignant and malignant epithelia of cheek mucosa
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γ-羟丁酸诱发的大鼠失神性癫痫持续发作诱导丘脑Fos癌蛋白表达
FOS oncoprotein expression in y-hydroxybutyrate-induced generalized absence epilepsy in the thalamus of the rat
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结果肾盂输尿管癌蛋白激酶C阳性表达率为60.0%(27/45),多药耐药膜糖蛋白阳性表达率为62.2%(28/45)。
Results The positive rate for PKC and MDR PGP was 60.0 % ( 27 / 45 ) and 62.2 % ( 28 / 45 ) in renal pelvic and ureteral carcinoma respectively .
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Sloan-Ketteringvirusgeneproduct(Ski)是细胞核内的原癌蛋白,属于Ski/SnoN原癌基因超家族。
Sloan - Kettering virus gene product ( Ski ) is a unique nuclear pro-oncoprotein and belongs to the Ski / SnoN proto-oncogene family .
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进行性系统性硬化病患者外周血单个核细胞中癌蛋白的表达和NK亚群状况的研究
Study on Expression of Oncoproteins and Subsets of Natural Killer Cells in the Peripheral Blood Mononuclear Cells from Patients with Progressive Systemic Sclerosis
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方法采用免疫组织化学卵白素生物素过氧化物酶连接法(SABC)对45例肾盂输尿管癌蛋白激酶C(PKC)、多药耐药膜糖蛋白表达进行对比研究。
Methods The expression of PKC and MDR PGP was detected by using immunohistochemical SABC method in 45 cases of renal pelvic and ureteral carcinoma .
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B-myb在早期乳腺癌蛋白表达的意义及其与ER、Ki-67的相关性研究
Expression and Significance of B-myb and its Relationship with ER and Ki-67 in Early Breast Cancer
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C-myc、Ha-ras和Ki-ras癌蛋白在HBsAg阳性的慢性肝脏疾病患者外周血单个核细胞中的表达
Expression of c-myc , Ha-ras and Ki-ras oncoproteins in peripheral blood mononuclear cells from HBsAg positive patients with chronic liver diseases
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抑癌蛋白P53是目前已知与人类肿瘤发生发展最为密切相关的分子之一,也是控制细胞增殖、凋亡的蛋白网络的节点分子。
P53 tumor suppressor protein is known as one of the most closely related with human carcinogenesis , and has become the key protein in the protein-protein network controlling cell cycle progression and cell apoptosis .
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通过体外对Nlp功能研究显示它可使细胞癌变,提示这是一种原癌蛋白。
In vitro analysis of the function of Nlp indicated that it conferred on cells tumorigenic properties , suggesting that it was an oncogenic protein .
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结论:脑胶质瘤相关的癌蛋白NF-κBp65对VEGF表达具有正向调节作用,促进肿瘤血管的生成,使脑胶质瘤不断恶化。
Conclusion NF - κ Bp65 as a oncogenic protein related to brain gliomas may have positive regulation on VEGF and promote the tumor angiogenesis and deterioration .
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原癌蛋白Pim-1激酶-GST融合蛋白的纯化及其激酶活性的分析
Purification of Proto-oncogene Pim-1 Kinase-GST Fusion Protein and Analysis of Its Kinase Activity
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采用免疫组化法和DNA缺口末端标记法观察Rb抑癌蛋白、增殖细胞核抗原(PCNA)和凋亡细胞在宫颈癌变过程中的表达。
Using immunohistochemical staining and DNA nick end labelling method , the expressions of Rb antioncogene protein , proliferating cell nuclear antigen ( PCNA ) and apoptotic cells were observed for their role in carcinogenesis of cervical cancer .
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探讨EB病毒基因组编码的癌蛋白LMP1对鼻咽癌细胞中转移相关基因表达的影响。
This paper was to investigate the effect of EB virus encoded latent membrane protein 1 ( LMP1 ) on expression of metastasis associated genes in nasopharyngeal carcinoma .
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本文报告了进行性系统性硬化病(PSS)患者外周血单个核细胞中C-myc、Ki-ras和Ha-ras三种癌蛋白的表达和NK细胞亚群的检测结果。
Expression of C-myc , Ki-ras and Ha-ras oncoproteins and subsets of natural killer ( NK ) cells in the peripheral blood mononuclear cells from patients with progressive systemic sclerosis ( PSS ) were studied .
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检测粪便中K-ras突变及胰液细胞学辅以检测抑癌蛋白表达在胰腺癌筛选和诊断中的价值
Detection of K-ras Mutations in Stools and Detection of Anti-oncogene Products as an Adjunct in Cytologic Examination of Pure Pancreatic Juice for Scanning and Diagnosis of Pancreatic Carcinoma
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目的探讨SV40早期区域基因编码产物大T抗原(Tag)的表达及与抑癌蛋白p53,pRb的相互作用在人脑肿瘤发生发展中的意义。
AIM To study the expression of SV40 early region gene coding product , the large tumor antigen ( Tag ), and its interaction with tumor suppressors p53 and pRb in human brain tumorigenesis .
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目的探讨蛋白转导结构域(PTD)介导的转导bcr/abl癌蛋白片段的方法,为进行免疫治疗提供实验依据。
Aim To explore the method of transfering oncoprotein bcr / abl , mediated by protein transduction domain ( PTD ), in order to provide the experimental basis for immune therapy .
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原癌蛋白(protooncogene)PIM(ProvirusIntegrationsiteforMoloneymurineleukemiavirus)激酶在细胞生存、增殖、分化和凋亡以及肿瘤发生和发展过程中有重要作用。
Protooncogene PIM ( Provirus Integration site for Moloney murine leukemia virus ) kinases have been shown to have diverse biological roles in cell survival , proliferation , differentiation and apoptosis , as well as play an important role in tumor occurrence and development .
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研制抗HER-2/Neu癌蛋白(p185)的单克隆抗体,并研究该基因过量表达与腋窝淋巴结阴性乳腺癌(ANNBC)预后的关系,以研制国产HER-2/Neu表达诊断试剂。
Purpose : To produce a new monoclone antibody against HER-2 / Neu oncoprotein ( p185 ), and to explore the relationship between HER-2 / Neu abnormal expression and prognosis of axillary lymphnode-negtive breast cancer ( ANNBC ) .
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新的卵巢上皮性癌蛋白标志物的初步研究
A Pilot Study of Novel Serum Tumor Marker of Ovarian Cancer
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食管鳞癌中候选抑癌蛋白14-3-3σ结合蛋白的蛋白质组研究
Proteomic Analysis of a Candidate Tumor Suppressor Protein 14-3-3 σ Associated Protein in Esophageal Squamous Cell Carcinoma