细胞滋养层

胎盘的正常发育依赖于细胞滋养层细胞增殖动态平衡，和分化为合体滋养细胞和侵袭性细胞滋养层细胞的动态平衡。

Normal development of the placenta depends on the orchestrated balance of cytotrophoblast cell proliferation and differentiation into either one of the differentiated cell types , syncytiotrophoblast or invasive cytotrophoblasts .

P53蛋白主要定位于细胞滋养层。

P53 protein was detected mainly in the cytotrophoblast .

目的：研究核因子-κB（NF-κB）在离体培养的人早孕期细胞滋养层细胞激活的机制。

Objective : To investigate the mechanism of NF - κ B activation in human cytotrophoblastic cells ( CTB ) isolated from the first trimester placenta .

游离绒毛细胞滋养层基底膜LN呈阴性；

Basal membrane of floating villi , LN is negative ;

天花粉蛋白对体外无血清培养的人早期绒毛细胞滋养层细胞hCG，孕酮分泌的影响

The Inhibitory Effect of Trichosanthin on hCG and Progesterone Production by Human First Trimester Placenta Explants and Cytotrophoblast In Vitro

结果：正常早孕绒毛中CX43阳性颗粒定位于细胞滋养层细胞的胞浆和胞膜中，胞核也有表达；

Results : CX43 positive particles were exclusively localized in cytotrophoblasts in normal early pregnancy villi .

结果HBEGF主要存在于细胞质，合体滋养层和细胞滋养层均有表达，部分流产滋养细胞不表达。

Results HB-EGF expression was localized in the cytoplasm of cytotrophoblast and syncytiotrophoblast , but no expression was present in those with spontaneous abortion .

目的探讨佛波酯（PMA）诱导细胞滋养层细胞（CTB）MMP-9基因表达的调控机制。

Objective To explore the regulatory mechanism of matrix metalloproteinase-9 ( MMP-9 ) gene expression induced by phorbol 12-myristate 13-acetate ( PMA ) in cytotrophoblastic cells .

结论高浓度ActA可诱导人细胞滋养层细胞发生凋亡，其作用可能主要是通过细胞凋亡的线粒体途径来实现的。

Conclusions High concentration of ActA can induce cell apoptosis in human cytotrophoblasts which might be mediated by the mitochondria signaling pathway .

结论：骨髓基质细胞滋养层是残留白血病细胞生存和再生长的微环境，可能通过上调bcl－2基因表达增强其抗药能力。

Conclusion : Bone marrow stromal layer was the vital microenvironment for the residual leukemic cells to survive and regrow , and might increase the drug resistance by up regulating bcl 2 gene expression .

2例同时检测出上述10种基因。结论IGFs可能在早期细胞滋养层的侵入、增殖分化、胎盘形成和胚胎生长发育过程中以自分泌或旁分泌方式发挥重要的调节作用。

Conclusion IGFs appear to play important regulation roles in early invasion , proliferation and differentiation of cytotrophoblast , and in the formation of placenta and the development of embryo via autocrine or paracrine way .

在母胎界面的细胞滋养层上高表达的HLA-G能够抑制子宫蜕膜NK细胞的杀伤活性，在保护胎儿不被母体排斥的过程中具有重要的作用。

HLA-G , which is high expressed on the cyto trophoblast cells at the maternal-fetal interface , plays an important role in the maternal-fetal tolerance and in protecting the fetal not being rejected by maternal by inhibiting the cytolysis of NK cells in the deciduas of uterus .

利用胶质细胞滋养层进行分离式原代神经元培养

Method of separate culture of primary neurons using glial feeder layer

胚胎干细胞滋养层的制备

Preparation of murine embryonic fibroblasts as the feeder-cell of embryonic stem cells

不同浓度激活素A对细胞滋养层细胞行为的影响

Effect of Activin A with Different Concentration on Behavior of Cytotrophoblast Cells

表皮生长因子对人胎盘细胞滋养层细胞增殖和功能的调控机制

Regulation of proliferation and function by EGF in human placental cytotrophoblast cell

绒毛组织由合体滋养层及细胞滋养层及中间的疏松间质三部分所构成。

Villi syncytiotrophoblast layer and cytotrophoblast and loose in the middle of stromal part .

早孕绒毛细胞滋养层细胞分离培养的实验研究

In vitro culture of human cytotrophoblasts isolated from early pregnancy villi Tom Clancys Splinter Cell

目的：研究补肾益气方对人早孕细胞滋养层细胞增殖和早期凋亡的影响及其可能的信号转导通路。

Objective : To investigate the mechanism of kidney-replenishing herb on the proliferation and apoptosis in human cytotrophoblasts .

本研究的目的是了解细胞滋养层细胞和合胞体滋养层细胞体外分化和生物学特性。

The objective of this study was to determine the differentiation and biological characterization of cytotrophoblastic celis and syncytiotrophoblastic celis in vitro .

人胎盘绒毛膜绒毛的结构由内向外依次是绒毛基质，细胞滋养层细胞和其外层的合体细胞滋养细胞。

The bulk of the human placenta consists of branching chorionic villi with an outer syncytiotrophoblast , underlying cytotrophoblasts , and a stromal core .

目的探讨补肾益气方对正常早孕期人细胞滋养层细胞增殖、侵袭、分化等生物学行为的影响。

ObjectiveTo investigate the effect of Chinese drugs for tonifying Shen on the bioactivity , cell proliferation , invasion and differentiation of human cytotrophoblast of early pregnancy .

结果自然流产组细胞滋养层细胞及合体滋养层细胞表达TNF-α均显著强于正常妊娠组（P<0.01）。

Results : We observed that the intensity of the immunohistochemistry signal of TNF - α in syncytiotrophoblastic and cytotrophoblastic cells of aborters was substantially higher than that of normal pregnant women ( P < 0.01 ) .

为使原代培养神经元能长期健康地生长发育，并且易于分离、纯化，本文利用胶质细胞滋养层进行胶质细胞与神经元分离式培养。

In order to obtain primarily cultured neurons that can live longer and are healthy , and easy to be isolated and purified , the glial feeder layers are used for culturing the primary neurons separated from the glial cells .

结果：IGF-I及其受体在大鼠内膜腺、腔上皮，蜕膜细胞及滋养层细胞中均有表达。

Results : IGF-I and its receptor expressed in luminal and glandular epithelium , decidual cell and trophoblast cell . PR was located in same cells as IGF-I and IGF-IR .

HBsAg及HBcAg在胎盘中分布由蜕膜细胞、滋养层细胞、绒毛间质细胞，绒毛毛细血管内皮细胞依次递减，羊膜上皮细胞中可检出HBsAg及HBcAg。

HBsAg and HBcAg was detected amniotic epithelium in part of placenta . It in the part of placenta increased gradually from deciduas cell to capillary endothelium . HBsAg and HBcAg were detected in amniotic epithelium .

早期胚泡中LN主要分布在内细胞团，滋养层细胞间质中也有分布。

LN chiefly distributed in the inner cell mass and between trophoblasts in early blastocyst .

TH1型/TH2型细胞因子对滋养层及蜕膜内分泌功能的影响

Effect of T_H 1-type / T_H2 type cytokines on endocrine functions of trophoblast and decidua in vitro

MSCs是造血支持细胞，作为滋养层支持造血干细胞的生长。

, and BM-derived MSCs also can be served as a cell feeder layer to support the growth of hematopoietic stem cells .

结论1.妊娠过程中，NKT细胞可能是滋养层分泌细胞因子的主要细胞。2.原因不明自发性复发性流产的发生，可能与NKT细胞失调相关。

In the course of pregnancy , NKT cells may be the major secreting cells in the trophoblast.2.Unexplained recurrent spontaneous abortion occurred , may be related to NKT cells disorders .