肌萎缩侧索硬化
- 网络amyotrophic lateral sclerosis;ALS
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MRI无创、敏感和直观的优势使其在肌萎缩侧索硬化的诊断上具有极大应用前景。
With non-invasive , sensitive and macroscopic advantages , MRI has great potentials in the diagnosis of ALS .
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MRI技术包括常规MRI、磁共振波谱、弥散张量成像和血氧水平依赖成像已经应用于肌萎缩侧索硬化的临床诊断及相关研究。
MRI techniques including conventional MRI , MRS , DTI and BOLD have been applied in the clinical diagnosis and related studies in ALS .
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MRI及MR扩散张量成像对肌萎缩侧索硬化症的初步评价
Preliminary assessment of amyotrophic lateral sclerosis by using MRI and MR diffusion tensor imaging
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91例肌萎缩侧索硬化症的F波和神经传导研究
F-wave and Nerve Conduction Studies in 91 Patients with Amyotrophic Lateral Sclerosis
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联合应用MR分光镜成像和弥散张力MRI,使肌萎缩侧索硬化患者变性的皮质脊髓束成像
Combined MR spectroscopic imaging and diffusion tensor MRI visualizes corticospinal tract degeneration in amyotrophic lateral sclerosis
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肌萎缩侧索硬化(ALS)很少见。
Amyotrophic lateral sclerosis ( ALS ) is uncommon .
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肌萎缩侧索硬化(AmyotrophicLateralSclerosisALS)是一个致命的神经变性疾病。
Amyotrophic lateral sclerosis ( ALS ) is a common progressive neurodegenerative disease in central nervous system .
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肌萎缩侧索硬化症(amyotrophiclateralsclerosis,ALS)是一组选择性侵犯运动神经元的慢性进行性变性疾病。
Amyotrophic lateral sclerosis ( ALS ) is a chronic progressive neurodegenerative disease by the selective death of motor neurones .
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坐在轮椅上的霍金还坦率地讲到他与ALS(肌萎缩侧索硬化症)做的斗争。
Hawking , who is confined to a wheelchair , also spoke candidly about his battle with ALS .
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前言:目的:探讨肌萎缩侧索硬化ALS合并颈椎病患者的临床特征。
Aim : To explore the clinical characteristics of amyotrophic lateral sclerosis ( ALS ) with cervical spondylosis .
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肌萎缩侧索硬化(ALS,amyotrophiclateralsclerosis)是一种以脑和脊髓的运动神经元进行性变性为特征的神经肌肉疾病。
Amyotrophic lateral sclerosis ( ALS ) is a progressive neuromuscular disorder characterized by degeneration of motor neurons in the brain and spinal cord .
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目的研究不同阶段肌萎缩侧索硬化(ALS)患者的定量肌电图(EMG)表现,寻找早期诊断ALS的敏感电生理指标。
Objective To study the quantitative electromyography in patients with ALS of different stages and determine the sensitive parameters for early diagnosis .
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目前多用于脑卒中及肌萎缩侧索硬化,但对PEG置放的时机、风险和对延长存活期的价值仍需更多的循证医学研究。
PEG is mostly used for stroke and amyotrophic lateral sclerosis , although more evidence-based researches are required to assess the timing , risks , and survival benefits .
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肌萎缩侧索硬化(amyotrophiclateralsclerosis,ALS)是一种支配随意运动的上下运动神经元选择性受累的神经系统变性疾病。
Amyotrophic lateral sclerosis ( ALS ) is a progressive neurodegenerative disease , selectively involving the upper and lower motor neurons that control voluntary movement .
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肌萎缩侧索硬化症SOD1基因突变特点
Feature of Mutation of SOD1 Gene in Amyotrophic Lateral Sclerosis
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目的初步探讨磁共振扩散张量成像(DTI)在肌萎缩侧索硬化症(ALS)诊断中的临床意义。
Objective To explore the clinical value of MR diffusion tensor imaging ( DTI ) in patients with amyotrophic lateral sclerosis ( ALS ) .
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美国渐冻症协会表示,2014年风行的冰桶挑战募集了大量资金,已经帮助科学研究发现了与渐冻症相关的重要基因。渐冻症是渐进性神经退行性疾病,学名为肌萎缩侧索硬化症(ALS)。
The Ice Bucket Challenge that went viral in 2014 has funded an important scientific gene discovery in the progressive neurodegenerative disease ALS , the ALS Association says .
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肌萎缩侧索硬化(amyotrophiclateralsclerosis,ALS)是一种选择性累及上、下运动神经元的慢性进行性致死性神经系统变性疾病,其病因和发病机制尚不清楚。
Amyotrophic lateral sclerosis ( ALS ) is a fatal neurodegenerative disease characterized by progressive and selective death of upper and lower motor neuron , the etiology and pathogenesis are still unclear .
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根据病变累及部位及病程可分为许多类型,其中最主要的有肌萎缩侧索硬化(amyotrophiclateralsclerosis,ALS)和进行性脊肌萎缩症(Progressivemuscularatrophy,PMA)。
According to the involved area and illness course , MND can be divided into several types , but amyotrophic lateral sclerosis ( ALS ) and progressive muscular atrophy ( PMA ) are the main types .
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肌萎缩侧索硬化症(amyotrophiclateralsclerosis,ALS)是一种慢性进行性神经系统变性病,以上、下运动神经元变性为特征。
A Study of Transcranial Magnetic Stimulation Motor Evoked Potentials on Amyotrophic Lateral SclerosisBackground : Amyotrophic lateral sclerosis ( ALS ) is a progressive neurodegenerative disease affecting both lower and upper motor neurons ( UMN ) .
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目的描述肌萎缩侧索硬化症(ALS)的脑部MR影像学表现特点,探讨常规MR成像及MR扩散张量成像(DTI)部分各向异性(FA)值在本病诊断中的价值。
Objective To describe the characteristic MR findings in the brain in patients with amyotrophic lateral sclerosis ( ALS ), and to assess the diagnostic value of conventional MR imaging and fractional anisotropy ( FA ) of diffusion tensor imaging ( DTI ) .
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目的:利用微孔膜器官型脊髓组织片培养的方法,加入适当剂量的线粒体功能抑制剂丙二酸钠,造成选择性运动神经元数目减少从而建立肌萎缩侧索硬化症(ALS)的体外器官模型。
Objective : To establish an in vitro model of amyotrophic lateral sclerosis ( ALS ) from the organotypic culture of SD rats ' lumber spinal cord induced by the mitochondrial inhibitor , malonate sodium .
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人内源性逆转录病毒与散发型肌萎缩侧索硬化相关性研究三个新的人内源性逆转录病毒(HERV)相关基因的研究
Study on Association between Human Endogenous Retrovirus and Sporadic Amyotrophic Lateral Sclerosis Identification and Characterization of Three Novel Human Endogenous Retrovirus-related Genes
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霍金的一生,包括他与肌萎缩侧索硬化症(亦称“ALS”或卢伽雷氏病)的战斗,已于2014年被拍摄成由埃迪·雷特梅尼领衔主演的电影《万物理论》。
Hawking 's life , including his battle with amyotrophic lateral sclerosis -- known as ALS or Lou Gehrig 's disease -- was made into a 2014 biopic , " The Theory of Everything , " starring Eddie Redmayne
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肌萎缩侧索硬化症(amyotrophiclateralsclerosis)属运动神经元病的一种,该病选择性损害脊髓前角运动神经细胞、脑干颅神经运动神经核细胞、以及大脑运动皮质锥体细胞。
Amyotrophic lateral sclerosis ( ALS )) is one of the motor neural diseases , which selectively affects motor neurons in the anterior horn of spinal-cord , and the motor nuclei of brainstem and the pyramidal cells in the motor cortex of brain .
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白血病抑制因子治疗组AMPA受体在脑干运动皮质的表达和肌萎缩侧索硬化对照组对比明显降低(P<0.01)。
Compared with the ALS control group , the expression of AMPA receptors in brain stem and sensorimotor cortex in the LIF treated group decreased significantly ( P < 0.01 ) .
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本研究旨在探讨肌萎缩侧索硬化(ALS)新的诊疗手段,即质子磁共振波谱(1H-MRS)在患者的临床应用价值和ALS患者的谷氨酸测定。
Our study assessed potential clinical usefulness of proton magnetic resonance spectroscopy ( 1H-MRS ) in amyotrophic lateral sclerosis ( ALS ) patients , and analyzed levels of plasma and cerebrospinal fluid ( CSF ) glutamate in ALS patients .
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目的观察脐血间质干细胞(UCB-MSCs)移植对肌萎缩侧索硬化(ALS)患者血浆及脑脊液谷氨酸(Glu)浓度的影响。
Aim : To observe the effect of transplantation of umbilical cord blood mesenchymal stem cells ( UCB-MSCs ) on glutamate ( Glu ) level in plasma and CSF of amyotrophic lateral sclerosis ( ALS ) patients .
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到目前为止,已确定在20%fALS和4%的散发性肌萎缩侧索硬化(sALS)中有SOD1基因突变,其突变数目已超过100种。
So far , 20 percent of fALS and 4 % Sporadic amyotrophic lateral sclerosis ( sALS ) have the SOD1 gene mutation and more than 100 kinds of mutation have been identified .
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结论中国南方人群肌萎缩侧索硬化症患者可能不存在SOD1基因第1~5号外显子突变或突变率极低,可能存在其他位点的基因突变。
[ Conclusion ] There may exists no mutation in exon 1 to 5 of SOD1 gene in all ALS patients and control in South Chinese , indicating that it may present some new gene mutation caused the ALS in South Chinese .