肠功能紊乱

福氏志贺菌感染后大鼠肠功能紊乱模型建立以及肠道通透性变化和肠黏膜IL-1β表达

Establishment of a Rat Model of the Post-dysenteric Bowel Dysfunction , Then the Change of Gut Permeability and IL-1 β in the Gut Mucosa

结果条件刺激和非条件刺激结合3次后，条件刺激即可稳定地诱发模型动物肠功能紊乱，持续达2h以上。

Results Conditioned stress , combined with non conditioned stressors for three times , induced steadily gastrointestinal dysfunction in animal lasting for more than 2 h.

成都利尔-肠炎、慢性腹泻、肠功能紊乱，婴幼儿腹泻。

Chengdu Lear-enteritis , chronic diarrhea , intestinal disorders , infantile diarrhea .

大鼠肠道一过性线虫感染致持续性肠运动功能紊乱

Persistent intestinal motility disorder after transient intestinal nematode infection in rats

结论DSS结肠炎是一种以肠黏膜免疫功能紊乱为主的炎症性病变。

Conclusion DSS induced colitis was a inflammatory disease characterized by predominant colonic immune disturbance .

背景：肠易激综合征（IBS）是以肠平滑肌功能紊乱为主要表现的多因素疾病，目前神经和胃肠激素在其发病机制中的作用甚受关注。

Background : Irritable bowel syndrome ( IBS ) is a multifactorial disease which is characterized by the dysfunction of intestinal smooth muscle . Now the roles of neural hormone and gastrointestinal hormone played in the pathogenesis of IBS are noticed .

结论认识应激状态下肠屏障功能的变化及其机理对临床上治疗应激引起的肠功能紊乱以及预防由此所诱发的严重并发症具有重要的临床意义。

Conclusion Recognizing the changes and pathogenesis have an important clinical significance for treating and preventing the intestinal barrier dysfunction induced by stress .

结果提示，运动源性自由基产生增加使肠组织中游离巯基被氧化，导致Na+-K+-AT-Pase活性下降，可能是造成运动性肠功能紊乱的重要因素。

After exercise . These suggested that increase of exercise induced free radicals led to Free SH of intestine cross link , which resulted in the decline of Na + K + ATPase activity . These might be important causes of exercise-induced intestine disorder .

目的：肠易激综合征（Irritablebowelsyndrome，IBS）是由腹部不适或腹痛同时伴有排便异常为主要表现的一组肠功能紊乱综合征，缺乏明显的形态学和生化异常改变。

Objective : Irritable bowel syndrome ( IBS ) is a derangement of bowel function syndrome characterized by abdominal pain with abnormal defecation , without the conspicuous change of morphology and biochemistry .