肺炎克雷伯杆菌

肺炎克雷伯杆菌β-内酰胺酶的分子特性

Molecular characteristics of beta-lactamase from Klebsiella pneumoniae

肺炎克雷伯杆菌分泌因子及活菌诱导人肺上皮细胞表达分泌IL-8的研究

Role of Secretory Factors and Live Bacteria of Klebsiella pneumoniae Induced IL-8 Expression in Human Lung Epithelial Cells

建立幼龄SD大鼠肺炎克雷伯杆菌肺炎模型的一种新方法

A New Method of Establishing a Model of Immature SD Rats Pneumonia Induced by Klebsiella Pneumoniae

肺炎克雷伯杆菌对小鼠中性粒细胞表达IL-1β和TNF-α的影响

Effects of Klebsiella pneumoniae on the expression of cytokines by polymorphonuclear neutrophil granulocytes in mice

特异性IgY对小鼠肺炎克雷伯杆菌肺炎有保护作用。

Specific IgY has potential to pneumonia of mice caused by K. pneumonia .

结论：肺炎克雷伯杆菌感染在体内能诱发肺内各细胞损伤和c-fos转录和表达上调，在加重COPD形成中有重要作用。

Conclusion : Klebsiella Pneumoniae infection can cause lung varied cells injury and increase c-fos protein and mRNA expression , and it play an important role in aggravating COPD .

体外抑菌试验表明，特异性IgY浓度在1～20mg/ml之间能抑制肺炎克雷伯杆菌的生长且呈剂量依赖性，但其活性低于阳性对照头孢哌酮。

Specific IgY at concentrations of 1 ~ 20 mg / ml inhibited the growth of K. pneumonia in a dose dependent manner .

目的观察肺炎克雷伯杆菌（klebsiellapneumoniae，Kle.p）感染对小鼠中性粒细胞细胞因子表达的影响。

Objective To observe the effect of Klebsiella pneumoniae ( Kle . p ) on the expression of cytokines in mouse polymorphonuclear neutrophil granulocytes ( PMNs ) .

大肠埃希菌及肺炎克雷伯杆菌中产超广谱β-内酰胺酶（ESBLs）阳性率分别为67.6%、42.8%。

The proportion of producing extended spectrum β - lactamases ( ESBLs ) in Escherichia coli and Klebsiella pneumoniae was 67.6 % and 42.8 % respectively .

目的：研究产超广谱β-内酰胺酶（extended-spectrumβ-lactamase，ESBL）肺炎克雷伯杆菌与新生儿呼吸机相关性肺炎（ventilator-AssociatedPneumonia，VAP）的关系。

Objective : To study the relationship between extended-spectrum β - lactamase ( ESBL ) - producing Klebsiella pneumoniae and neonatal ventilator-associated pneumonia ( VAP ) .

目前国内关于肺炎克雷伯杆菌的药敏、耐药情况以及ESBLs表型检测等方面报道较多，而血清型检测、分布及相关研究少见。

Currently on the susceptibility of Klebsiella pneumoniae , drug resistance and phenotypic detection of ESBLs reported more areas , while serotype detection , distribution and research rare .

摘要：目的对一起发生在某医院新生儿重症监护病房（NICU）的群体性肺炎克雷伯杆菌败血症进行调查和分析。

ABSTRACT : Objective To investigate and take a case study on a Klebsiella pneumoniae outbreak in a newborn intensive care unit ( NICU ) .

结果：本实验中31/70株（44.29%）肺炎克雷伯杆菌和30/84株（35.71%）大肠埃希氏菌检出产ESBLs。

Results : In this experiment , 31 of the 70 strains ( 44.29 % ) of Klebsiella pneumonia and 30 of the 84 strains ( 35.71 % ) of Escherichia coli produced ESBLs .

目的了解我院产超广谱β-内酰胺酶（ESBLs）大肠杆菌、肺炎克雷伯杆菌对临床常用抗生素的耐药情况，为临床治疗和控制ESBLs菌感染提供依据。

Objective To investigate the antibiotic resistance of ESBLs-producing Escherichia coli and Klebsiella pneumoniae to 12 kinds of antibacterial drugs in our hospital , provide bases for clinical control and treatment of ESBLs bacteria infection .

革兰阴性杆菌以肺炎克雷伯杆菌最常见，产ESBL菌株比例高，占60%（24/40）。

Klebsiella pneumonia was the most common Gram negative bacilli with 60 % of extended spectrum β lactamase ( ESBL ) producing strains ( 24 / 40 ) .

其中K1、K2型肺炎克雷伯杆菌的抗嗜中性白细胞之吞噬作用及抗细胞内杀伤作用强于非K1、K2型，因此，K1、K2型流行率较高，毒性较强。

Where K1 , K2 Klebsiella pneumoniae anti-type neutrophils and phagocytosis and intracellular killing effect against stronger than non-K1 , K2 type , therefore , K1 , K2-based prevalence of high toxic .

应用吸烟加反复肺炎克雷伯杆菌感染法建立大鼠慢性阻塞性肺疾病（COPD）模型。

In order to observe the treatment effect of Chinese herb 814 on chronic obstructive pulmonary disease ( COPD ) induced by smoke in combination with Klebsiella Pneumoniae , a rat COPD model was established by smoking and repeatedly intranasal infection .

NDM-1基因多存在于大肠杆菌（36份）和肺炎克雷伯杆菌（111份）中，携该基因的细菌对除替加环素和黏菌素外的抗生素普遍耐药。

NDM-1 was mostly found among Escherichia coli ( 36 ) and Klebsiella pneumoniae ( 111 ), which were highly resistant to all antibiotics except to tigecycline and colistin .

目的：观察头孢地嗪（CDZ）对肺炎克雷伯杆菌（Kle.p）感染小鼠中性粒细胞释放活性氧以及细胞凋亡的影响。

Objective : To study the effects of cefodizime ( CDZ ) on superoxide production and neutrophil apoptosis response to heat_killed Klebsiella pneumoniae ( Kle . p ) in mice .

39例碳青霉烯耐药的肺炎克雷伯杆菌感染的临床分析

Clinical Analysis of 39 Patients with Carbapenem Resistant Klebsiella Pneumoniae Infection

小儿肺炎克雷伯杆菌肺炎的临床与药敏试验研究

Clinical and drug-sensitivity study of Klebsiella pneumoniae pneumonia in children

肺炎克雷伯杆菌性肝脓肿的早期诊断与治疗研究

Study of Klebsiella Pneumoniae Liver Abscess in the Early Diagnosis and Treatment

肺炎克雷伯杆菌感染引起大鼠小气道炎症的免疫学特征

Immunological Characterization of Small Airway Inflammation of Rats Induced by Klebsiella Pneumoniae

肺炎克雷伯杆菌感染患儿心肌酶的改变及临床分析

Clinical analysis of myocardial enzyme change in child patients with Klebsiella pneumoniae infection

此外，花盖红菇的乙酸乙酯提取物比其他红菇的提取物对大肠杆菌、革兰氏阳性芽孢杆菌、肺炎克雷伯杆菌和枯草芽孢杆菌具有更好的抑菌效果。

Coli , Bacillus sp. , Klebsiella pneumoniae and Bacillus subtilis than other extracts .

病原以细菌检出为主，其中G-菌占优势，前三种G-菌分别为副流感嗜血杆菌、大肠埃希菌、肺炎克雷伯杆菌。

The previous gram-negative bacteria were Haemophilus parainfluenzae , Escherichia coli and Klebsiella pneumonia .

糖尿病合并肺炎克雷伯杆菌性肝脓肿的临床特点及误诊分析

Clinical Analysis and misdiagnosis of Bacterial Liver Abscess In Diabetics Caused By Klebsiella Pneumoniae

方法采用气管内注入感染法建立肺炎克雷伯杆菌性大鼠肺炎模型。

METHODS The male wistar rats were infected with Klebsiella Pneumoniae by the intratracheal route .

肺炎克雷伯杆菌超广谱β-内酰胺酶检测及耐药性分析

Detection of extended-spectrum β - lactamases and analysis of antibiotic resistance in clinical isolates of klebsiella pneumonia

目的探讨老年人肺炎克雷伯杆菌肺炎早期诊断及治疗。

Objective To discuss the early diagnosis of treatment of patients with pneumonia due to Klebsiella pneumoniae infection .