胆汁反流

目的观察胆汁反流对胃内pH值的影响。

Objective To observe the effect of bile reflux on the intragastric pH.

健康青年人24h胃内pH和胆汁反流同步监测

Synchronous 24-hour Intragastric pH and Bile Reflux Monitoring in Young Healthy Subjects

反流性食管炎食管内pH值与胆汁反流的关系

The relationship between intraesophageal pH and bile regurgitation in reflux esophagitis

胆汁反流性胃炎的HP感染率降低。

H. pylori infection rate of blie reflux gastritis is cut down .

危重病人24h动态胃内pH和胆汁反流监测的研究

A Study of 24 hour ambulatory acid and bilirubin measurements in critically ill patients

结果表明，抗H.胆汁反流与胃粘膜屏障

Anti - h. bile reflux and gastric mucosal barrier

结论胆汁反流可能抑制了Hp感染和消化性溃疡的发病。

[ Conclusion ] The peptic ulcer and Hp infection should be inhibited by bile reflux .

经X~检验，两组胆汁反流，胃癌均有显著差异（P0.01）。

There was notable difference in bile regurgitation and stomach cancer between the two groups after x ~ 2 tests .

结论病理性酸反流和胆汁反流的破坏作用是导致GERD的重要原因。

Conclusion Pathological acid reflux and bile reflux lead to GERD .

胆汁反流在GERD食管黏膜损害中起重要作用。

Bile reflux may play a significant role in esophageal mucosal damage of GERD .

目的采用不透X线标志物法（ROMs）检测胃固体排空功能，探讨胃固体排空障碍在胆汁反流性胃炎（Bilerefluxgastritis，BRG）中的存在和作用。

Objective To detect the delay of gastric emptying in bile reflux gastritis with radio-opaque markers .

和降冲剂对实验性胆汁反流性胃炎大鼠血清胃泌素、胃窦粘膜PGE2含量的影响

Effects of Hejiang Oral Solution on Content of the Serum Gastrin and PGE2 in Bile Reflux Gastritis Rats

结果：治疗组的临床症状改善、胃炎痊愈情况明显优于对照组（P＜0.01），对胆汁反流的疗效两组比较无明显差异（P＞0.05）。

Results : The clinical improved symptom and The treated gastritis of treatment group are superior to that of control group ( P0 . 01 ) . there is no significant difference about bile reflex between two groups ( P0.05 ) .

GERD患者中有20例（34%）胆汁反流阳性（混合反流）；

20 ( 34 % ) of 59 patients with GERD showed positive bile reflux ( mixed reflux ) .

目的探讨危重病人胃内pH值变化及是否伴有胆汁反流，为应激状态下急性胃黏膜病变（AGML）的防治提供理论依据探讨。

[ Objective ] To explore the changes of intra-gastric acid and with or without duodenogastric reflux ( DGR ) in critically ill patients .

两组患儿治疗4周后24h胃内胆汁反流监测各指标与治疗前相比差异均无统计学意义（均为P>0.05）。

All the parameters of 24-hour gastric bilirubin monitoring were not significantly decreased after 4 weeks of treatment in two groups ( P > 0.05 ) .

方法：应用Bilitec2000便携式胆红素监测仪和pH监测仪同步监测48名健康青年志愿者的24h胃内pH和胆汁反流情况。

Methods : Forty-eight young healthy volunteers were investigated in this study . 24-hour intragastric pH and bile reflux monitoring were performed with ambulatory bilirubin monitor ( Bilitec 2000 ) and pH monitor synchronously .

结果表明：胃手术方式对胆汁反流可产生重要影响，残胃粘膜组织学异常改变与胃液胆酸浓度、pH的升高以及胃内菌量的增多有关。

It was shown that the methods of gastric surgery play an important role affecting the bile reflux , and the abnormal histology of gastric mucosa was closely related to the bile acid concentrations , PH and TBC in the gastric juice .

目的：探讨健康青年人生理性DGR的发生特点，并为其24h胃内胆汁反流监测提供正常参考值范围。

Aims : To investigate the characteristics of physiological DGR in young healthy subjects , and to define a referential range for 24-hour intragastric bile reflux monitoring .

治疗前后两组患者24h胃内胆汁反流总时间百分比均有明显下降（P<0.01），两组间变化率也有显著差异（P<0.05）。

The total time percentage of 24-hour intragastric bile-reflux had both greatly decreased after treatment ( P < 0.01 ) . The two groups variety rates had significant differences ( P < 0.05 ) .

结果46例胆汁反流性胃炎中HP阳性率26.09%，48例非胆汁反流性胃炎中HP阳性率62.15%，两组相比有显著性差异（P0.01）。

Results Helicobacter pylori infection was 26.09 % among 46 patients with bile reflux gastritis and 62.15 % among 48 patients with non - bile reflux gastritis . Significant different was found between the two groups ( P0.01 ) .

免疫组化染色显示应激性溃疡大鼠胃内胆汁反流增加时，幽门区肌间神经丛nNOS免疫反应阳性产物平均光密度值显著增高（P<0.01）。

Accompanied by the increased bile reflux , the mean optical density of nNOS-positive products significantly increased in the nerve plexus of pyloric sphincter ( P < 0.01 ) .

研究胆汁反流性胃炎患者胃内pH值与胆汁反流的关系。胆汁反流性胃炎患者22例，应用便携式pH及胆汁监测仪同步监测胃内24h的pH值及胆红素吸收值。

To study the relationship between gastric pH and bilirubin absorption value in bile reflux gastritis , we simultaneously assessed the changes in gastric pH and bilirubin absorption value during 24h in 22 patients with bile reflux gastritis using ambulatory 24h pH meter and bilirubin monitoring technique .

计算3个胆红素吸收（BA）界值下的胆汁反流时间百分比，分析各时段胆汁反流参数的特点，同时行pH值与BA值的相关性分析。

Within three thresholds for bilirubin absorbance ( BA ), the percentages of bile reflux period were calculated , and the bile reflux parameters in different periods were analyzed . The changes of pH and BA value were studied to analyze the relationship between them .

方法：应用带胃管的便携式pH监测仪和Bilitec2000，同步监测14例原发性病理性DGR患者和15名健康志愿者的胃内24h胆汁反流和pH变化情况。

Methods The status of bile juice reflux and pH values in the stomach were measured simultaneously for 24 hours by ambulatory pH monitor and bilirubin monitor ( Bilitec 2000 ) in 14 patients with primary pathologic DGR and 15 healthy volunteers .

目的证实应激过程中胆汁反流的存在，探讨胆囊收缩素八肽（CCK-8）在应激所致胆汁反流中的作用及相关机制。

Objective To illustrate the existence of bile regurgitation under stress condition , and explore the possible effects and related mechanism of changes of cholecystokinin octapeptide ( CCK-8 ) on stress-induced bile regurgitation in rats .

目的研究食管胆汁反流的发生情况，探讨其与酸、碱反流的关系及其对胃食管反流病（GERD）的诊断意义。

Objective To investigate the incidence of esophageal bile reflux and its relationship with acid or alkaline reflux and to evaluate the significance of detecting bile reflux in the diagnosis of gastroesophageal reflux disease ( GERD ) .

结果反流性食管炎组与慢性胃炎伴胆汁反流组的Hp检出率均较低，两组间差异无显著性，但与十二指肠溃疡组Hp检出率的差异有显著性（P<0.05）。

Results There was no significant difference in the low detection rate of positive Hp between reflux esophagitis ( RE ) and chronic gastritis with bile reflux groups but tended to increase with age increment ( P < 0.05 ), for these two groups and the duodenal ulcer group .

胆汁反流对大鼠食管粘膜炎症损伤和凋亡的作用

Reflux of Bile Induces Esophageal Mucosal Inflammation and Apoptosis in Rats

胃苏颗粒治疗胆汁反流性胃炎疗效观察

Clinical Observation of " Weisu Granule " in Treating Bile-Reflux Gastritis