胍类化合物
- 网络Guanidine compound;Guanidines
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结果和结论:合成了13个胍类化合物,其结构经IR1、HNMR、MS和元素分析得到确证;
Results And Conclusion : Thirteen guanidine compounds were synthesized , and their structures were confirmed by IR ,() ~ ( 1 ) H NMR , MS and elemental analysis .
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1-烷基-3-[4-(苯并噻唑-2-巯基)苯基]胍类化合物的合成及其生物活性
Synthesis and bioactivity of 1-alkyl-3 - [ 4 - ( benzothiazole-2-mercapto ) phenyl ] guanidine compounds
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目的:合成1-烷基-3-[4-(苯并噻唑-2-巯基)苯基]胍类化合物,寻找有一氧化氮合酶(NOS)抑制活性的新型化合物。
Aim : To synthesize 1-alkyl-3 - [ 4 - ( benzothiazole-2-mercapto ) phenyl ] guanidine derivatives to search for new-type compounds with NOS inhibitory activity .
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胍类化合物的制备及在有机合成中的应用
Preparation of Guanidines and Their Application in Organic Synthesis Cooling Compounds
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3-取代色酮类化合物及五碳糖基胍类化合物的合成研究
Study on the Synthesis of 3-Substituted Chromone Derivatives and Pentosyl Guanidines
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肝脏疾病患者血浆胍类化合物含量的变化
Changes of guanidino-compounds in the plasma of patients with various liver diseases
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一氧化氮供体N-芳基-N′-羟基胍类化合物的合成
Synthesis of N-Aryl-N ′ - Hydroxyguanidines , a New Class of NO Donors
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本文综述了胍类化合物的合成进展。参考文献32篇。
The methods of synthesis of guanidine derivatives were reviewed with 32 references .
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胍类化合物存在于许多具有生物活性的化合物中。
Guanidine moiety is an important feature commonly found in many biologically active compounds .
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支持向量机用于胍类化合物Na/H交换抑制活性的模式识别
Support vector machine applied to the pattern recognition of guanidines as Na / H exchange inhibitors
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胍类化合物的合成进展
Progressing in the Synthesis of Guanidines
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综述了胍类化合物的制备及其在有机合成中的应用.特别着重合成方法研究的近期进展及在不对称合成中的应用。
In this paper , the preparation of guanidines and their application in organic synthesis , especially the advances of synthetic methods in recent years and the application in asymmetric synthesis , are briefly reviewed .
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二硫戊环胍类和脒类化合物的合成及其iNOS/PAF双重抑制活性
Studies on Synthesis and iNOS / PAF Dual Inhibitory Activity of Dithiolane Guanidine and Amidine Compounds
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方法:以N-苯基胍为母核,在苯基对位引入苯并噻唑-2-巯基,胍中其他氮上分别引入烷基、环烷基、芳烷基等,并测定这些胍类化合物的NOS抑制活性。
Methods : Using N-phenyl guanidine as a basic structure , a series of guanidine derivatives were obtained by introducing benzothiazole-2-mercapto at the para position of phenyl group , and alkyl , cycloalkyl , aralkyl at the N atom of guanido , and their NOS inhibiting activities were evaluated .