胶原酶

CT引导下胶原酶注射颈椎间盘溶解术的临床研究

Clinical Study of Treating Cervical Disc Herniation by CT-guided Collagenase Injection

CT引导下神经根周围阻滞配合胶原酶溶核治疗腰椎间盘突出症

CT-guided Collagenase Chemonucleolysis of Lumbar Disc Herniation Combining with Perineural Root Block

CT引导下硬膜外靶位注射胶原酶治疗腰椎间盘脱出

Percutaneous collagenase chemonucleolysis by CT-guide in lumbar intervertebral disc extrusion

单纯胶原酶组（C组）；

Group of collagenase ( C group );

CT引导下经骶管裂孔胶原酶溶解术治疗腰椎间盘突出症198例

The collagenase nucleolysis through hiatus sacralis guided by CT for treatment of lumbar disc herniation

注入胶原酶V使胰腺充分膨胀。

Inject collagenase V to make the pancreas full of expansion .

前言：目的：研究CT引导下胶原酶注射颈椎间盘溶解术治疗颈椎间盘突出症的价值。

Objective : To study the values of treating the cervical disc herniation by collagenase under CT guiding .

目的探讨CT引导联合靶注射胶原酶定点髓核溶解术的临床应用价值。

Objective To study the clinical significance of the combined target-injection of collagenase by CT guided for local chemonucleolysis .

结论CT引导下经皮硬膜外靶位注射胶原酶治疗腰椎间盘脱出是一种操作准确、创伤小、安全有效的介入治疗方法。

Conclusion Percutaneous collagenase chemonucleolysis in CT position was a convenient , safe , efficient and minimal invasive technique .

重组副腺病毒介导的大鼠星状细胞激活相关蛋白基因转染对大鼠肝星状细胞表达间质胶原酶mRNA的影响

Effects of rAAV / rSTAP on mRNA level of interstitial collagenase in rat stellate cells

抗IV型胶原酶单链抗体在毕赤酵母中分泌表达

Expression of single chain antibody to collagenase IV by Pichia pastoris

采用酶谱方法检测IV型胶原酶对底物的降解。

Substrate degradation by type IV collagenase was measured by zymography .

方法支气管肺泡灌洗获取肺泡巨噬细胞，肺组织机械处理结合酶消化法（DNA酶、胶原酶）分离间质巨噬细胞；

Methods AMs were collected by lung lavage and IMs by treatment of the lung tissue with DNAse and collagenase .

用共扩增逆转录定量PCR方法测定间质胶原酶基因表达水平。

Interstitial collagenase gene expression level was mea-sured by quantitative analysis of reverse transcription polymerase chain reaction .

方法胶原酶消化GO和斜视患者眼球后结缔组织以获得RF；

Methods RF were obtained by digesting the retro-orbital connective tissue from GO patients and strabismic patients as normal controls with collagenase .

IL-6对分离培养的兔破骨细胞1型胶原酶mRNA表达的影响

Effect of interleukin-6 on expression of collagenase type 1 mRNA in isolated rabbit osteoclast in vitro

方法本实验用新生1～2d的SD大鼠颅盖骨，采用二次胶原酶消化法进行细胞体外培养。

Method Osteoblastic cells are isolated by sequential enzyme digestion from newborn SD rat calvaria .

目的：比较术前X片定位法和术中CT定位法行小关节内缘进针硬膜外前侧间隙注射胶原酶溶核治疗腰椎间盘突出症的穿刺过程和临床疗效。

Objective : To compare two different guidance techniques , X-ray before and CT during the chemonucleolysis for treatment of lumbar disc herniation .

转化生长因子β1对纤维母细胞Ⅰ、Ⅲ型前胶原及胶原酶mRNA表达的影响

Effects of transforming growth factor - β _1 on mRNA expressions of procollagen type ⅰ、ⅲ and collagenase of fibroblasts

结论：CT引导下神经根周围阻滞能有效预防由胶原酶溶核治疗腰椎间盘突出症所致的近期疼痛加重，操作简便、安全。

Conclusion : Perineural Root Block shows satisfactory precaution effects of early stage aggravated pain induced by collagenase chemonucleolysis , easy manipulation and safety .

目的：1、用两步消化法和试管纯化法初步建立用胶原酶P分离、纯化人胰岛细胞的方法；

Objective 1 . To establish an effective method for isolation and purification of the islet cells from human pancreata by using a two-step digestion and tube purification method .

抗癌抗生素力达霉素与抗IV型胶原酶单链抗体的基因工程组装融合蛋白

An engineered and assembled fusion protein of antitumor antibiotic lidamycin and scFv antibody directed against type IV collagenase

大鼠肠癌中Ⅳ型胶原酶及rasP21表达的研究

Study on type IV collagenase and ras p21 in colonic carcinoma of rats

用胶原酶灌注消化，收集小牛主动脉内皮细胞（EC）进行传代培养。

Arterial endothelial cells were obtained from bovine aorta by mild treatment with collagenase and medium perfusion .

结论CT导引联合注射胶原酶是治疗腰椎间盘突出症安全、有效的方法。

Conclusions CT-guided collagenase injection into the prominence of herniated lumbar disc and its surface is a safe and efficient method in the treatment of herniated lumbar disc .

运用AFM观测牙本质胶原纤维在胶原酶作用下的降解过程。

To observe the enzymatic degradation process of dentin collagen fibrils under the action of collagenase .

【方法】将25只供体SD雄性大鼠依胰腺分离或消化的方法不同随机地分为5组：①A组：胆总管灌注胶原酶P；

Methods 25 male SD rats ( islet donors ) were randomly divided into 5 groups based on different methods of separation or collagenase digestive approach .

用胰酶和胶原酶消化法从1～2d新生大鼠的心肌组织中分离心肌细胞，用细胞计数法测出不同的消化酶分离所得的心肌细胞数量。

Neonatal rat cardiac myocyte was isolated using trypsin and collagenase solution . The number of isolated cell was counted by cell counter .

用胶原酶和链霉蛋白酶灌注肝脏并分离急性肝损伤期各时间点的肝星型细胞，应用半定量聚合酶链反应（RT-PCR）研究zf-9mRNA的表达。

The pronase-collagenase perfusion of liver was used to isolate HSC , and the expression of zf-9 mRNA was examined by RT-PCR .

目的：探讨CT引导下椎间盘突出的髓核内和突出物表面注射胶原酶治疗椎间盘突出症的效果。

Objective : To investigate the effectiveness of CT guided collagenase injection into nucleus pulposus of herniated lumbar disc and the surface of herniation in the treatment of lumbar disc herniation .