脱颗粒

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  • degranulation
脱颗粒脱颗粒
  1. 补体C5导致中性粒细胞脱颗粒

    Complement component C5 induce neutrophils degranulation

  2. 电镜见PMC与LFb紧密接触和部分PMC有脱颗粒现象。

    It was usually found that the PMC contact closely with LFb and some PMC showed the degranulation .

  3. 结论R2具有止痒、抗炎、抑制Ⅰ、Ⅳ型变态反应作用,其机制与抗组胺、稳定肥大细胞膜及抑制肥大细胞脱颗粒等有关。

    One of its mechanisms may be related to the actions of antihistamine , stabilizing mastocyte membrane and inhibiting degranulation of mastocyte .

  4. 精神心理因素异常与肠黏膜MC含量增加及肠黏膜MC的脱颗粒有关。

    The abnormal psychosocial factors are correlated with the increased number and degranulation of mucosal MC .

  5. IgE介导的肥大细胞脱颗粒信号转导途径的研究进展

    Recent advances on the signal transduction pathway of IgE mediated mast cell degranulation

  6. 基于此种现状,本课题拟用化合物48/80探讨肥大细胞脱颗粒与载脂蛋白E基因敲除小鼠主动脉斑块的关系。

    Based on the status , compound 48 / 80 and apolipoprotein E-knockout mice were used to investigate the effect of mast cell degranulation on plaque .

  7. 结论ECP是嗜酸粒细胞活化后脱颗粒释放的主要炎性介质,是反映支气管哮喘气道炎症发生发展的重要指标之一。

    Conclusion ECP is an important chemokine secreted by activated eosinophil cells .

  8. 本文主要介绍PLD在呼吸爆发、脱颗粒及花生四烯酸(AA)释放等方面的研究进展。

    This review introduces the recent advances of PLD in respiratory burst , degranulation and arachidonic acid release .

  9. 目的:研究用Ⅰ型变态反应的有效拮抗药物:色甘酸钠作对照,研究藿香正气口服液在抗原(αIgEHRP)再次刺激前、后,对肥大细胞(MC)脱颗粒的作用。

    Objective : To explore the effect of mast cell before or after stimulation of antigen (α IgE HRP ) .

  10. 方法采用改良甲苯胺蓝染色法检测120例患者胃粘膜中MC计数及脱颗粒细胞所占比例。

    Methods The improved toluidine blue pigmentation was used to examine the number of gastric mucosal MC and its degranulation portion of 120 patients .

  11. 过敏性哮喘的脱颗粒指数(DI)显著高于正常人,并且脱敏治疗1年能显著降低其D1。

    The DI after one year 's desensitization treat-ment with fungal allergens is markedly lowered than be-fore ( P < 0.001 ) .

  12. 电镜:Ⅰ、Ⅱa组腹胰和Ⅱb组背、腹胰腺细胞粗内质网脱颗粒、融合和扩张。

    Electron microscope : In ventral pancreas of Group ⅰ and ⅱ a and the dorsal and ventral pancreas of Group ⅱ b , the rough endoplasmic reticulum of the acinar cells showed granules-scaling , fusion and dilatation .

  13. 在胃粘膜应激损伤过程中,MMC和CTMC脱颗粒率均明显增高,其中MMC的反应更为灵敏。

    The reactivity of MMC to stress-induced gastric mucosal injury was more sensitive than that in CTMC .

  14. 方法以CD63/CD203c/CD45抗体组合,建立用FCM分析户尘螨致敏的嗜碱性粒细胞脱颗粒的方法。

    Methods The protocol for FCM analysis of basophil degranulation in allergy to dust mite by CD63 / CD203c / CD45 combination was established .

  15. 结果:藜子70%醇提物400mg/kgig可明显抑制大鼠同种被动皮肤过敏反应及颅骨膜肥大细胞脱颗粒;

    Results : FC 400mg / kg ig significantly inhibited homologous PCA and degranulation of mast cells of calvarial periosteum in rats .

  16. 结果:HBO处理可以减轻大鼠同种被动皮肤过敏反应和小鼠的异种被动皮肤过敏反应,还可以抑制干酪素引起的小鼠肥大细胞脱颗粒反应。

    Results : HBO treatment could alleviate both the rat homo passive skin allergic reaction and the mice hetero passive skin allergic reaction ;

  17. 结果①Hp阳性患者胃粘膜MC计数及脱颗粒比显著高于Hp阴性患者(P<0.01);

    Results ① The count of gastric mucosal MC and its degranulation portion of patients with H.pylori positive were significantly higer than those with H.pylori negative ( P < 0.01 ) .

  18. 这一点也被光镜和电镜下所见到的哮喘患者局部抗原激发后BALF中的肥大细胞脱颗粒现象所证实。

    Mast cell degranulation was also observed under light - or electro - microscopy in the BALF from the patients with asthma following local allergen challenge .

  19. 许多炎症因子、化学介质和趋化因子参与,其中IgE作为主要的介质在嗜酸性粒细胞激活和脱颗粒过程中起关键性作用。

    There are a lot of inflammatory cytokines , chemical medium and chemokines in NP , including IgE , which plays a key role in the eosinophil activation and degranulation .

  20. 目的:观察异位性皮炎急性病损中嗜酸性粒细胞的脱颗粒蛋白主要碱性蛋白(MBP)的表达情况。

    Objective : Our aim was to study the deposition of major basic protein ( MBP ) in the lesions of atopic dermatitis ( AD ) .

  21. TSPN组与Nx组腹腔肥大细胞脱颗粒率无明显差异。

    Between TSPN group and Nx group the degranulation rate of peritoneal mast cells had no significant difference .

  22. 在大鼠颅骨骨膜接种抗血清使肥大细胞被动致敏,观察LMWH对OA引起肥大细胞脱颗粒的影响;

    The effects of LMWH on the degranulation of pericranium mast cell induced by OA were observed through the passive anaphylaxis rat model which was made by vaccinating antiserum at pericranium ;

  23. 针灸对Ⅰ型变态反应患者嗜碱细胞脱颗粒试验(HBDT)的影响

    Acupuncture Effect on Human Basophilic Degranulation Test in Allergy Type I

  24. 选取胃溃疡(GU)21例,十二指肠溃疡(DU)23例,作HE和GABE液染色,研究GU和DU胃壁内肥大细胞数量、分布和脱颗粒率与溃疡发生的关系。

    The count of mast cell and degranulation in gastric wall of 21 cases of gastric ulcer ( GU ) and 23 cases of duodenal ulcer ( DU ) have been studied .

  25. 目的:研究内脏高敏感大鼠肠道及脊髓内的5-羟色胺(5-HT)能神经元及神经纤维的分布,肥大细胞脱颗粒对5-HT能神经元及神经纤维的影响。

    Objective : To investigate the distribution of serotoninergic neurons and fibers in the spinal cord and colon of visceral hypersensitivity rats , and the effect of degranulation of mast cell reaction on the serotoninergic neurons .

  26. 我们首先用Alcian蓝染色的肥大细胞脱颗粒试验和用荧光测定组胺的方法观察了天花粉蛋白对肥大细胞脱颗粒和组胺释放的影响。

    The effect of trichosanthin on mast cell degranulation and histamine release were observed with both Alcian blue staining method and fluorescent histamine determination method .

  27. SCZ能延长4AP诱发小鼠舔体反应的潜伏期,减少小鼠舔体反应的次数;对大鼠颅骨骨膜肥大细胞脱颗粒有明显抑制作用;

    The licking response induced by 4-AP in mice , the mast cell degranulation of skull in rats could be inhibited significantly .

  28. TOA管内浓度25和50μg/ml能显著抑制亲同种细胞抗体介导的大鼠肠系膜肥大细胞脱颗粒和腹腔肥大细胞组胺释放。

    At the concentrations of 25 and 50 μ g / ml , TOA inhibited homocytotropic antibody-mediated degranulation of mast cells in the rat mesentery , and also inhibited anaphylactic histamine release from rat peritoneal mast cells .

  29. 类过敏反应是通过直接激活肥大细胞(MC)/嗜碱性粒细胞(Basophil)或直接作用于补体系统,使靶细胞脱颗粒释放过敏介质,从而引发局部或系统性的过敏症状。

    Anaphylactoid reaction is through activating mast cells / basophils directly or activating the complement system , it makes the target cells degranulated and release allergy mediators , therefore , it can cause local or systemic allergy symptoms .

  30. 目的:血小板活化因子(PAF)可诱导嗜酸性粒细胞(EOS)脱颗粒产生低密度嗜酸性粒细胞(HE),本研究旨在探讨地塞米松、茶碱对上述过程产生的影响。

    AIM : To elucidate the effects of platelet-activating factor ( PAF ) on eosinophil activation and the action of dexamethasone or theophylline during this process . METHODS : Eosinophils ( EOS ) from the peripheral blood of normal subjects were isolated .