血蓝蛋白

与已发现的抗菌肽不同的是这3种肽带负电荷，与血蓝蛋白C端序列的一致性达95%100%，由此表明它来自对虾呼吸作用蛋白血蓝蛋白的裂解片断。

The peptides display 95 % to 100 % sequence identity with a C terminal sequence of hemocyanin indicating they are cleaved fragments of the shrimp respiratory protein . Contrary to the cationic antimicrobial peptides , the three antifungal peptides present a negative net charge at physiological pH.

血蓝蛋白与IgSF同源关系的研究

Investigation of Homology Between Hemocyanin and IgSF Molecules

日本（虫寻）（Charybdisjaponica）血蓝蛋白的分离纯化及其酚氧化酶样生物化学性质的研究

Purification of Hemocyanin from Charybdis Japonica and Biochemical Properties of Hemocyanin Derived Phenoloxidase-Like Enzyme

Cu是甲壳动物体内必需的微量营养素，不仅是酚氧化酶、超氧化物歧化酶活性中心的重要因子，也是合成血蓝蛋白的必需成分，但是高浓度的铜亦会对生物体会产生毒害作用。

Copper is a essential micronutrients of the crustaceans . It is not only a phenoloxidase and superoxide dismutase activity center factor , but also an essential component of hemocyanin . However , high concentrations of copper will produce toxic effects on crustacean .

重氮化法使对氧磷（E600）与牛血清白蛋白（BSA）、血蓝蛋白偶合合成人工抗原。

Paraoxon ( E600 ) was conjugated to bovine serum albumin ( BSA ) or tachypleus tridentatus hemocyanin ( TTH ) by diazotization .

在F雄性大鼠腹腔注射血蓝蛋白（KLH），研究T细胞依赖抗原初始免疫反应对中枢神经系统羟色胺（HT）代谢的影响。

To study the effects of a primary immune response to T-cell dependent antigens on central serotonin ( - HT ) metabolism , keyhole limpet hemocyanin ( KLH ) was administered intraperitoneally to F male rats .

河豚毒素（TTX）与钥孔（？）八肽胆囊收缩素对经钥孔戚血蓝蛋白免疫小鼠T淋巴细胞亚群的影响

Tetrodotoxin ( TTX ) was conjugated to keyhole limpet hemocyanin ( KLH ) via formaldehyde as the coupling agent to render its immunogenic . Cholecystokinin octapeptide modulates T-lymphocyte subsets in KLH-immunized mice

方法：以P4为半抗原，与血蓝蛋白（LPH）化学偶联制备人工抗原（P4LPH），并以其免疫BALB/c小鼠，制备抗P4的mAb。

METHODS : P4 was coupled chemically with Limulus polyphemus hemocyanin ( LPH ) to form a coupling agent P4 LPH , and then BALB / c mice were immunized with the P4 LPH .

方法：以TTX为半抗原，与中国鲎血蓝蛋白（TTH）化学偶联制备人工抗原（TTXTTH）；

Methods : TTX was coupled to Tachypleus tridentatus hemocyanin ( TTH ) in presence of formaldehyde to form an artificial antigen ( TTX-TTH ), with which the BALB / c mice were immunized .

方法：将Aβ42多肽与匙孔虫戚血蓝蛋白（KLH）偶联，免疫新西兰白兔从而产生抗-Aβ42多克隆抗体。

Methods New Zealand rabbits were immunized with synthetic A β 42 peptide coupled to keyhole limpet haemocyanin ( KLH ) for the production of the polyclonal anti-A β 42 antibody .

锯缘青蟹血蓝蛋白酚氧化酶活性研究

Studies on Phenoloxidase Activity of Hemocyanin in Scylla serrata

血蓝蛋白分子的结构、分类及其在进化上的演变

Hemocyanian : Its Structure , Classification and Evolution

呼吸蛋白是一种能够可逆性地结合氧并将氧气运输至深层组织的特殊蛋白，包括三类：血蓝蛋白、血红蛋白、蚯蚓血红蛋白。

The respiratory protein can reversibly bind oxygen for transport to the deep tissue .

血蓝蛋白模型化合物的合成和性质

Synthesis and properties of hemocyanin model compounds

从血蓝蛋白的分子结构、功能特性、合成和代谢方面综述了国内外海洋节肢动物血蓝蛋白的研究进展。

The molecular structure , function property and anabolism of hemocyanins of Arthropod both domestic and abroad are summarized .

血蓝蛋白一种浅蓝色的含铜的呼吸色素，类似血红蛋白，出现在某些节肢动物及软体动物的血液之中。

A bluish , copper-containing respiratory pigment similar to hemoglobin , present in the blood of certain mollusks and arthropods .

本研究采用凝集抑制实验和亲和蛋白质组学等方法探索凡纳滨对虾血蓝蛋白与病原菌的凝集作用靶标。

In this study , we used agglutination inhibition assay and affinity proteomic technology to further investigate the agglutinative target of hemocyanin .

本文综述了双核铜酶，特别是酪氨酸酶、血蓝蛋白的结构，键合氧、活化氧的性能及有关仿酶模型的研究进展。

This review deals with the active site structure , reactivities and chemical mimics of the binuclear copper enzymes , particularly hemocyanin and tyrosinase .

铁蛋白和血蓝蛋白都是含有金属离子的多功能蛋白，能直接或者间接的参与生物体内重金属离子的脱毒作用，并参与生物体多种生理生化的反应以及各种金属蛋白和酶类的合成。

Ferritin and hemocyanin are multifunctional proteins which both contain metal ions , they directly or indirectly involve in detoxification of heavy metal ions in vivo role and participate in a variety of physiological and biochemical responses of organisms and a variety of metal proteins and enzymes synthesis .

当免疫刺激大鼠4天后，其下丘脑匀浆5羟色胺水平出现降低，同时应用在体脑微透析技术研究发现清醒大鼠腹腔注射血蓝蛋白4天后，其下丘脑前叶细胞外液的5羟色胺水平增加。

A decrease in hypothalamic 5-HT levels was observed on Day 4 following stimulation of the immune system . In the anterior hypothalamus , a concomitant increase in the basal extracellular 5-HT levels was measured by using in vivo microdialysis in awake rats on Day 4 following KLH administration .

锯缘青蟹血淋巴和血蓝蛋白免疫活性研究急性白血病非血缘脐血造血干细胞移植后早期免疫重建的研究

The Study of Immune Reconstitution in Patients with Acute Leukemia Following Unrelated Cord Blood Stem Cell Transplantation

三刺鲎（Tachypleustridentatus）血淋巴的研究1.血蓝蛋白的分离及其免疫原性的研究

Studies on the horseshoe crab ( tachypleus tridentatus ) hemolymph 1.separation and immunogenicity of hemocyanin