解离常数

用NMR方法测定三羟甲基胺基甲烷的质子解离常数

Determination of proton dissociation constant of tris - ( hydroxymethyl ) - aminomethane by NMR method

对特异性好的适配子进行亲和力分析，测定解离常数（Kd）。

The affinities of the specific aptamers were determined by measurement of dissociation constant ( Kd ) .

N，N′&二（间甲苯基）乙二胺的合成及其酸式解离常数的测定

SYNTHESIS AND DETERMINATION OF ACID DISSOCIATION CONSTANTS OF N , N ′ - bis ( m-tolyl ) ethylenediamine

荧光法测定β－CD与萘酚负离子包结物的解离常数和β－CD与分子型萘酚包结物的酸式离解常数

Determination of Dissociation Constants and Acid Dissociation Constants of β - CD-Naphthol Complexes by fluorescence Method

Excel电子表格在电位法测定酸解离常数中的应用

Application of Excel in Acidic Dissociation Constants Determination

几种异羟肟酸的酸解离常数测定和W（Ⅵ）&异羟肟酸配合物的合成及表征

Determination of dissociation constants of some hydroxamic acids and synthesis and characterization of tungsten (ⅵ) - hydroxamic acid complexes

表观解离常数（Kd）在纳摩尔范围内，在生物应用中具有足够的敏感性。另外，多种生物体中重要的金属离子对1的荧光没有影响，如Ca2+、Mg2+等。

Apparent dissociation constant ( Kd ) was in the nanomolar range , which afforded sufficient sensitivity for biological applications .

通过已经得到的微观解离常数和宏观解离常数，计算得到了20℃下各微观离子的浓度分率值随pH值的变化关系。

Finally , the relationship between the relative concentrations of all creatine micro-species and the pH values of the solution at given temperature were determined by using macro - and micro-dissociation constants .

对不同取代基的苯甲酸钠盐，其相应的酸解离常数和溶度参数与PET的结晶速率有一定的内在联系。

In the case of the sodium benzoates with different substituted groups , the crystallization rate of PET is related to the dissociation constant and solubility parameter of the substituted benzoates .

方法：运用放射性配基受体结合法测定不同动物心房肌和心室肌M受体密度及解离常数（Kd）值。

METHODS : Using radioligand binding assay , the M-receptor density and dissociation constant were observed in atrial and ventricular myocardium of above animals .

利用电流滴定的方法得出半胱胺自组装膜的表面解离常数（表面pKb）。

The surface pK-b of the self-assembled monolayers of cysteamine was obtained by the electrochemical titration method .

Pitzer方程在确定弱酸解离常数中的应用

The Application of Pitzer Equation to the Determination of Dissociation Constant of Weak Acid

介质对酸解离常数的影响&Tiron-NaNO3-C2H5OH-H2O体系，293.2K

The Influence of Medium on the Ionization Constants for Acids in Solution & The System Tiron-NaNO_3-C_2H_5OH-H_2O , 293.2K

DEEA、DBEA、DHEA共轭酸的解离常数pKa值的测定

Determination of the ionization constant of conjugate acids for deea , dbea and DHEA

根据光度法测定酸解离常数的原理，采用紫外分光光度法测定了厚朴酚与和厚朴酚的解离常数（pKa），并用计算机和统计方法作数据处理。

According to the principal of determination of acidic dissociation constant by spectrophotometry , the UV spectrophotometric method was used to determine the dissociation constants of magnolol and honokiol ( pKa ) .

结果：缓解期哮喘患者外周淋巴细胞β肾上腺素能受体最大结合量（Bmax）较正常人明显增高，平衡解离常数（Kd）亦增高，血浆cAMP水平无显著差异；

RESULTS : Bmax and Kd of β - adrenoceptors in asthma at remission stage were markedly higher than that in normal subjects , while cAMP levels in blood plasma were not different between them .

第一部分毛细管电泳法测定药物的理化常数本部分首先运用毛细管区带电泳法，以水杨酸为内标，通过采用两点pH比值消元法准确地测定了苯甲酸的酸碱解离常数（pKa）值。

Part 1 . Determination of physico-chemical constants of drugs by high performance capillary electrophoresis . Firstly , capillary zone electrophoresis was used to determine the acid-base dissociation constants of benzoic acid by the method two-point-pH-ratio elimination with salicylate as internal standard .

结果辐射可显著降低神经细胞中GABA受体生物结合活性，表现为GABA受体蛋白平衡解离常数（Kd）升高，结合活性降低。

Results 1.The drug binding activity of the GABA receptor was decreased and the equilibrium dissociation constant ( K-d ) was significantly increased compared with the negative control group 2 hr after irradiation , and a spike value appeared at 24 hr .

用ANS荧光滴定法研究发现，Pb~（2+）能降低膜ANS复合物的表观解离常数和增加膜上ANS的结合位点数。

By means of the titration of the membrane with ANS , it was found that Pb2 + decreased the apparent dissociation constant of ANS membrane complex and enhanced number of the ANS binding site in the membrane .

方法采用放射性配基饱和法，检测雄性SD大鼠性腺轴褪黑素受体的最大结合量（Bmax）和解离常数（Kd值）的冬夏变化。

Method The radioligand saturation method was used to detect the changes of maximal combination ( Bmax ) value and dissociation constant ( Kd value ) of melatonin receptor of sex gland axis in winter and in summer in male SD rats .

电磁脉冲照射后即刻大鼠海马中N-甲基-D-天冬氨酸受体的平衡解离常数开始下降，照后3h下降最显著（P<0.05），6h渐有恢复，48h恢复至正常水平；

The Kd of NMDA receptor began to decrease immediately after EMP exposure , which was the most obvious at 3 hours ( P < 0.05 ), followed then by gradual increase at 6 hours and reaching the normal level at 48 hours .

测得氧化苦参碱在水中溶解度大于1g／ml，电位滴定法和分光光度指示剂法测得氧化苦参碱的解离常数分别为6.98和6.71，真实正辛醇／水分配系数为0.2。

The water solubility for oxymatrine is more than 1g / ml. The pka value of oxymatrine determined by potential titration and spectrophotometric indicator method were 6.98 and 6.71 respectively . The n-octanol / water partition coefficient ( Po / w ) of oxymatrine was 0.2 .

首先在37℃环境下标定Ca2+探针indo-1的解离常数Kd值，根据荧光-浓度换算公式将测量的荧光强度值换算成Ca2+浓度值。

The dissociation constant values ( Kd ) of the fluorescent probe indo-1 was measured at 37 ℃, and accor - ding to the conversion formula from fluorescence intensity to concentration , the concentration of Ca 2 + was calculated .

与对照组相比，泻剂结肠的kappa阿片受体最大结合数明显增高（957.00±102.41vs459.00±52.41fmol/mg.p，P<0.01），解离常数无明显的差异。

As compared with the control group , the maximal binding capacity of kappa opioid receptor was significantly increased ( 957.00 ± 102.41 vs 459.00 ± 52.41 fmol / mg · p , P < 0.01 ), and no remarkable change of affinity was found in cathartic colon of rats .

对Marinsky最近提出的求得本征解离常数的外推法中所作的关于交换剂相中带电组分活度系数的假定，提出不同的看法，认为是不必要的。

The extrapolation procedure proposed by Marinsky for evaluation of the intrinsic dissociation constant has been examined and it is pointed out that the assumption of the activity coefficients of the charged species in the resin phase is not necessary .

弱酸性阳离子交换树脂112×1的本征解离常数

Intrinsic dissociation constant of cross-linked polymethacrylic acid resin 112 × 1

李沙育图形在弱酸解离常数测定中的应用

Appilication of Lissajous Figures in the Determination of Weak Acid-Dissociation Constant

目的测定葛根素的解离常数。

ObjectiveTo determine the first and second dissociation constants of puerarin .

测定醋酸解离常数中的误差分析

Analysis of Errors in Determining Dissociation Constant of Acetic Acid

电位滴定法测定两性树脂的表观解离常数

The determination of apparent dissociation constant on amphoteric resin by Potentiometric method