诺氟沙星

诺氟沙星与维生素C的配伍实验

The Compatibility Test of Norfloxacin and Vitamin C

土壤类型、温度和pH值对诺氟沙星吸附的影响

Effect of Soil Kinds , Temperature and pH on Adsorption for Norfloxacin in Soil

复方制剂中诺氟沙星的HPLC法测定

Determination of Norfloxacin in Compound Preparation by HPLC

诺氟沙星-铜（Ⅱ）-邻菲咯啉配合物的SOD活性及电化学性能

Electrochemical Properties and SOD-like Activities of Copper (ⅱ) Complexes with Norfloxacin and 1,10-Phenanthroline

新型PVC膜涂丝诺氟沙星选择电极的研制与应用

Preparation and Application of a Novel Norfloxacin Ion-selective Electrode Based on PVC Membrane Coated-wire

前言：目的：通过对诺氟沙星-聚维酮（FPA-PVP）共沉淀物在人体内药物动力学考察，为临床用药提供理论参考。

Objective : Pharmacokinetics of FPA PVP coprecipitate was studied in order to provide reference for clinical use .

诺氟沙星的HPLC测定

HPLC determination of Norfloxacin

方法：用CMCNa作凝胶基质，制备了诺氟沙星凝胶。

METHODS : The gel of norfloxacin was made mainly of CMC Na , besides norfloxacin .

诺氟沙星和环丙沙星的抗Uu活性最差。

Norfloxacin and Ciprofloxacin had the least activity against Uu .

本文报道了一种以诺氟沙星碘化物与碘化铋的分子缔合物为电活性物的新型PVC膜诺氟沙星选择电极。

A new PVC membrane-norfloxacin ( NFLX ) selective electrode based on NFLX iodide and bismuth iodide molecular association complex is reported .

土壤理化性质对诺氟沙星的土壤吸附影响主要表现为与pH的极显著负相关，与其他性质的关系不明显。

Soil properties on adsorption of norfloxacin major impact of soil pH was highly significant and negative correlation , the relationship with other properties is not obvious .

RP-HPLC同时测定中华绒螯蟹肝脏中诺氟沙星、环丙沙星和恩诺沙星残留

Simultaneous determination of norfloxacin , ciprofloxacin and enrofloxacin residues in liver of Eriocheir sinensis by RP-HPLC

其中耐药率最高的是多黏菌素B，达65.2%；诺氟沙星、头孢噻肟、磷霉素、林可霉素和呋喃妥因的耐药率也较高，均在30.0%以上。

The resistance rate of Polymyxin B is highest , up to 65.2 % . The resistance rate of Norfloxacin Cefotaxime , Fosfomycin , Lincomycin , and Nitrofurantoin is more than 30.0 % .

采用碳二亚胺法制备诺氟沙星与牛血清白蛋白（BSA）的结合物，作为诺氟沙星酶联免疫用的免疫原。

The antigenic conjugate of norfloxacin and bovine serum albumin ( BSA ) was prepared by carbodiimide method .

在NaCl含量0.85%～5.00%的培养基中能够生长；恩诺沙星、诺氟沙星对其有抑制作用。

It could grow in the solid culture added 0.85 % ~ 5.00 % NaCl and was inhibited by enrofloxacin and norfloxacin .

用梯度平皿法测定诺氟沙星、四环素、氯霉素和氨苄西林的MIC；

Gradient plates method was used to determine the MIC of norfloxacin , tetracycline , chloramphenicol and ampicillin .

分别用碳二亚胺法和混合酸酐法制备诺氟沙星与卵清蛋白（OA）的结合物，作为诺氟沙星酶联免疫测定用的包被抗原。

The conjugates of norfloxacin-ovalbumin ( OA ) used for coating antigen were synthesized by carbodiimide method and mixed anhydride method , respectively .

目的：探讨P-糖蛋白（P-gp）的药泵作用对小肠吸收诺氟沙星皈影响。

Objective : To study the influence of intestine P-glycoprotein drug pumping in rats on norfloxacin absorption .

方法：大鼠右侧脑室注射诺氟沙星150和300μg·kg~（-1）后，于皮层感觉运动区记录EEG并观察脑组织超微结构的变化。

METHODS : EEG was recorded in the sensorimotor area of rat cortex after Nor 150 and 300 μ g · kg-1 were injected into the right ventricle of the brain .

用紫外可见分光光度法研究了诺氟沙星（NFLX）的光谱特性及其金属络合物与鲱鱼精DNA的相互作用。

The interaction of metal complex of norfloxacin ( NFLX ) with herring sperm DNA and its characteristic were studied by UV and visible spectrophotometry .

本文研究了不同起始pH、温度下莲杆活性炭对水溶液中诺氟沙星的吸附能力，探明了经磷酸活化的莲杆活性炭对诺氟沙星吸附特性。

This paper studied the effect of initial pH , temperature lotus bar activated carbon to water solution chino-e norfloxacin adsorption capacity , proven by phosphoric acid activation of lotus bar activated carbon for norfloxacin adsorption characteristics .

目的：研究诺氟沙星（norfloxacin，NFLX）在清醒大鼠的神经毒性和毒代动力学。

AIM : To study the neurotoxicity and toxicokinetics of norfloxacin ( NFLX ) in freely moving rats .

方法：运用十二烷基硫酸钠聚丙烯酰胺凝胶蛋白电泳（SDS-PAGE）法和体外外翻小肠囊吸收实验研究大鼠小肠P-gp的药泵作用对诺氟沙星吸收的影响程度。

Method : Drug pumping effect of intestine P-glycoprotein in rats on norfloxacin absorption was studied by SDS-PAGE and everted sac absorption method in vitro .

试验结果表明：黄连提取物处理后，试验组菌体内诺氟沙星蓄积浓度明显高于空白组（P0.01），说明黄连具有促进菌体内药物蓄积的作用。

The result indicated that the accumulated concentration of medicine norfloxacin within the experiment strains which treated with coptis extract was clear high than blank space ( P < 0.01 ) .

DDDs最高DDDc最低的是诺氟沙星胶囊；

Norfloxacin capsules was the highest in DDDs and the lowest in DDDc ;

若规定可食用组织中的诺氟沙星最大残留限量为50μg/kg，在本实验条件下，建议临床休药期为10d。

Withdrawl time was 10d in the light of the maximum residue limit of 50 μ g / kg .

诺氟沙星对家蚕病毒性软化病发病过程的影响结论TGF-β1和IL-10参与了抗结核分枝杆菌（Mtb）感染的免疫过程；

Effect of Norfloxacin to the course of infected Infectious Flacherie Virus Silkworms Conclusion Both cytokine were involved in the course of anti-Mtb infectious immunity .

本文根据Tb3+能显著增强Ce（）-SO2-3-NFLX体系的化学发光，建立了流动注射铽敏化化学发光测定诺氟沙星的新方法。

A new flow injection chemiluminescence method for the determination of norfloxacin was established . It is based on the chemiluminescence reaction of Ce (ⅳ) SO 2 - 3 NFLX sensitized by Tb 3 + .

结果：诺氟沙星BPAA组大鼠EEG示痫样放电，并伴有局部抽搐和全身强直痉挛发作等行为学改变；

Results : The epileptiform discharges appeared in norfloxacin combined with BPAA group , accompanied with limb twitching and clonic tonic seizures .

建议饲喂磺胺嘧啶或诺氟沙星的甲鱼应在停药10d后上市。

It is suggested that the sulfadiazine - or norfloxacin-treated soft turtle be onto the market 10 d after withdraw medication .