转录激活
- transcription activation;transcriptional activation;activating transcription
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结论:在HeLa细胞中,对启动子具有转录激活活性的主要是CTCF的N段,而M段和C段几乎没有转录激活活性。
Conclusion : N domain of CTCF has transcription activation function in HeLa cells , while M and C domains have no such an activity .
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基因突变和转基因技术评价TLR-4信号受体在流体切应力诱导血管内皮细胞IL-8基因转录激活中的作用
Assessment of the Role of TLR-4 in Shear-Stress-induced IL-8 Gene Transcription Activation in Vascular Endothelial Cells by Gene Mutation and Gene Transfection Technology
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蛋白的N端对于转录激活活性是必需的。
The N-terminal of the protein is necessary for its activity .
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中国人雄激素受体N端转录激活区的测序及突变检测
Mutations in the N-terminal Transcriptional Activation Region of Androgen Receptor in the Chinese
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HBVx蛋白真核表达质粒的构建及其对反式转录激活作用的影响
Construction of HBV X mammalian expression plasmid and detection of transcriptional activity of HBV X protein
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真核细胞组蛋白N端赖氨酸残基的乙酰化与基因的转录激活有关。
Acetylation of lysine residues of core histone N terminal domains has been found correlatively associated with transcriptional activation in eukaryotes .
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此外,AR还受到多肽生长因子和细胞因子等的调节,表现激素非依赖型的转录激活活性。
Also AR is regulated by peptide growth factors and cytokines in a hormone independent manner .
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STAT(Signaltransducerandactivatoroftranscription)是存在于细胞质中的一类潜在的信号转导与转录激活因子。
STAT ( Signal transducer and activator of transcription ) proteins transduce signals for varieties of cytokines .
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砒石对哮喘小鼠信号转导和转录激活因子6及嗜酸粒细胞趋化因子mRNA表达的影响
Effects of arsenolite on expressions of signal transducer and activator of transcription 6 and eotaxin ( mRNA ) in asthmatic mice
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iNOS基因在胶质细胞中转录激活机制初探
Mechanism of Transcriptional Activation of iNOS in Glial Cell
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大鼠iNOS基因上游调控区在转录激活中的作用
Role of 5 ′ flanking Region of Rat iNOS Gene in Transcriptional Activation
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AF2具有雌激素依赖的转录激活功能,位于E/F区。
AF2 locates in the E / F region , with ligand-dependent transactivation function .
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CalpaininhibitorⅠ对糖皮质激素受体表达和转录激活作用的影响
Effects of Calpain inhibitor ⅰ on glucocorticoid receptor expression and its transcript activation ability
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应用酵母单杂交体系筛选与大鼠谷胱甘肽S-转移酶P增强子GPEⅠ相互作用的转录激活因子
Screening the trans-action Factors Binding to the Enhancer Element of Rat GST-P by Yeast One hybrid System
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低氧诱导因子(HIF-1)是细胞应激缺氧所产生的转录激活因子。
HIF-1 is a transcription activating factor generated by cells under stress and hypoxia .
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C-Jun蛋白对糖皮质激素受体表达及转录激活能力的影响
Effects of c-Jun on expression and transcriptional activation ability of glucocorticoid receptor
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福氏2a志贺菌DNA转录激活蛋白MarA的二级结构及其B细胞抗原表位预测
Prediction of the secondary structure and B cell epitopes for the DNA-binding transcriptional activator protein MarA of Shigella flexneri 2a
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人外周血活化淋巴细胞survivin基因的转录激活和表达相关的信号转导通路研究
The Transcriptional Activation of Survivin Gene in Human Peripheral Blood Activated Lymphocyte and Related Signal Transduction Pathway
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CBF转录激活因子及其在提高植物耐逆性中的作用
CBF Transcriptional Activators and Their Roles in Enhancing Stress Tolerance of Plants
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ChIP方法可用于证实MAR介导的转录激活,在实时检测方面比RT-PCR提供了更多动力学信息。
ChIP can be used to confirm the MAR-mediated transcriptional activation and provide more reliable information than RT-PCR in real time .
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在正常生长条件下,热激因子处于钝化的单体状态,而当热激时,热激因子形成三聚体并与DNA结合,同时通过转录激活域的活化而激活热激基因的表达。
HSF is present in a latent state under normal conditions ; it is activated upon heat stress by induction of trimerization , high affinity binding to DNA and transcriptional activity .
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结论c-Jun蛋白表达水平对GR的表达和转录激活活性有影响,抑制c-Jun蛋白表达,一定程度上可促进GR表达并增强其转录激活功能。
Inhibition of c-Jun expression could promote glucocorticoid receptor expression and its transcript activation ability .
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转录激活因子CBF在植物调节冷驯化中的作用
Role of CBF in Regulating Cold Acclimation in Plants
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相对荧光素酶活性法检测GR转录激活功能的变化。
The transcriptional activation activity of GR was evaluated through method of relative activity of luciferase .
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研究表明,NF-κB自身的苏氨酸磷酸化状态亦影响其转录激活活性,但未见在RS研究中的相关报道。
It is reported that threonine phosphorylation of NF - κ B also affects its transcriptional activity , but there is no report in the research field of RS.
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信号转导及转录激活因子(STAT)结构与功能研究进展
Progress on STAT-signal transducers and activators of transcription
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真核基因转录激活调控是在启动子、增强子等顺式调控元件和转录因子、激活因子以及RNA聚合酶II(PolII)等调控蛋白的参与下协同进行的。
The eukaryotic gene transcriptional activation by RNA polymerase II ( RNA pol II ) requires interaction between cis-acting regulatory elements and trans-acting factors .
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锌离子的结合被认为是p53转录激活所必需的,去除锌离子将降低p53DBD与DNA特异性结合。
Zinc coordination is thought to be necessary for transactivation and removal of zinc reduces the DNA-binding specificity .
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目的观察促进与抑制c-Jun蛋白表达对糖皮质激素受体(GR)表达和转录激活能力的影响,探索c-Jun与GR功能的相互关系。
Objective To investigate the effects of c-Jun on expression and transcriptional activation ability of glucocorticoid receptors .
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TGF-α、EGFR及信号转导和转录激活因子3在喉癌组织中的表达及相关性研究
Expression of EGFR 、 TGF - α、 Signal Transducers and Activators of Transcription 3 and Related Factors in Laryngeal Carcinoma