钙粘素

E钙粘素表达与肿瘤细胞分化呈正相关；

The expression of E-cadherin was associated with differentiation .

目的探讨细胞黏附分子E钙粘素和β连环素在宫颈癌组织中表达的意义。

Objective To investigate the cell adhesion molecule E-cadherin and β - catenin expression and the significance in cervical cancer .

E钙粘素相关蛋白在人肺腺癌组织中的表达

Expression of α - catenin in human lung adenocarcinoma

颞叶癫痫神经元型钙粘素mRNA表达研究

Expression of mRNA of neuronal cadherin followed temporal lobe epilepsy

目的：研究E钙粘素（Ecadherin）基因蛋白表达与口腔疣状癌发生发展的相关性。

Objective To determine the relationship between E cadherin over expression and progression in oral verrucous carcinoma .

目的探讨E钙粘素的表达与乳腺癌病理分级，临床分期的关系。

Objective To study the relationship between E cadherin ( E cad ) expression and the pathological grade , clinical stage in breast cancer .

E-钙粘素和CD（44）V6表达与食管癌预后的关系

Relationship of E-cadherin and CD_ ( 44 ) V6 expression and prognosis in esophageal carcinoma

分化型甲状腺癌组织中E钙粘素的表达显著低于癌旁组织，与甲状腺癌的组织类型无关；

The expression of E-cadherin in differentiated thyroid carcinoma was much lower than that in the para-tumorous tissue , which was uncorrelated with histological feature .

结果：E钙粘素和β连环素在正常早孕绒毛和葡萄胎组织中均有表达，在正常早孕绒毛组和葡萄胎非恶变组的表达强度差异无显著性（P0.05）；

Results : The positive expression of E-cadherin and beta catenin were detected both in the tissues of normal chorionic villus and hydatidiform mole .

浸润性乳腺导管癌组织中Ezrin和钙粘素E的表达与淋巴结转移的关系

Expression of Ezrin and E-cadherin in Invasive Ductal Breast Cancer and Their Correlations to Lymphatic Metastasis

棉铃虫钙粘素氨基酸序列与蜂翅目其它昆虫的钙粘素具较高同源性50%~80%，与人的E一型钙粘素同源性仅为22%。

The E-cadherin protein of cotton bollworm was 50-80 % identical to the E-cadherin from other insects , and 22 % identical to that from human .

结论钙粘素E的表达异常与膀胱肿瘤的恶性进展有关，可作为判断肿瘤复发及预后的指标。

Conclusion The aberrant expression of E-cadherin played an important role in the malignant progression of BTCC , and could be used as a predictor of the tumor recurrence and prognosis .

MEK-1对MCF-7乳腺癌细胞αV整合素和上皮钙粘素调节的表达

Expression of MEK-1 in regulation of α V integrin and E-cadherin of MCF-7 breast cancer cells

结论甲状腺癌组织VEGF、MMP-9及E钙粘素的表达与甲状腺癌的侵袭及转移有关，可作为甲状腺癌患者的预后指标。

Conclusion The expression of VEGF , MMP-9 , E-cadherin is associated with invasion and metastasis of thyroid carcinoma , which may serve as prognosis indexes of thyroid carcinoma .

结论E钙粘素介导的细胞细胞粘附作用可通过调控细胞周期以及细胞凋亡，影响肺腺癌A549细胞对ADM的敏感性，在肿瘤群集耐药中发挥作用。

Conclusion E-cadherin-mediated enhancement of intercellular adherence can function in multicellular resistance of lung adenocarcinoma A549 cells through influencing cell cycle , apoptosis , and susceptibility to ADM.

目的：研究MEK1在MCF7乳腺癌细胞对αV整合素（αVintegrin）和上皮钙粘素（Ecadherin）调节的表达。

Purpose : Expression of MEK-1 was studied by regulating α V integrin and E-cadherin on MCF-7 breast cancer cells .

E-钙粘素及PI3K信号转导通路在肿瘤多细胞耐药中作用机制的研究

A Preliminary Study on the Mechanism of the Role of E-cadherin and PI3K Signal Transduction Pathway in Multicellular Resistance of Tumor Cells

目的：探讨E-钙粘素（E-Cd）及p53在壶腹周围癌中的表达，及与壶腹周围癌的分化、浸润及转移的关系。

Objective : To study the relationship between expressions of E-cadherin ( E-Cd ) and p53 and differentiation , infiltration and metastasis of peri-ampullar carcinoma .

本研究通过检测Ezrin和钙粘素E（E-cadherin）在浸润性乳腺导管癌中的表达情况，探讨其在淋巴结转移中的意义。

This study was performed to detect the expression of Ezrin and E-cadherin in primary invasive ductal breast cancer in order to evaluate their possible roles in lymphatic metastasis .

研究表明，Twist蛋白是属于碱性的螺旋-环-螺旋蛋白家族中的高度保守的转录因子，可以通过下调肺癌中上皮钙粘素的表达而促进上皮间质化。

It has been known previously that up-regulation of Twist , a highly conserved basic helix-loop-helix transcription factor , in lung cancer cells can promote epithelial to mesenchymal transition through down-regulation of E-cadherin .

方法应用单克隆抗体的SABC免疫组织化学方法，观察79例乳腺导管癌组织标本中上皮性钙粘素（E-cad-herin）的表达。

Methods SABC immunohistochemistry was used to detect expression of E cadherin in 79 patients with breast ductal carcinoma and 8 normal subjects .

目的观察上皮性钙粘素（E-cadherin）在乳腺导管癌组织中的表达，分析其与肿瘤侵袭及腋下淋巴结转移的关系。

Objective To observe the expression of E cadherin in breast ductal carcinoma and to analyze the relationship between the expression and the invasion and oxter lymph node metastasis .

CIK细胞对人胃癌裸鼠腹膜移植瘤细胞增殖、凋亡及E-钙粘素、β1整合素表达影响的实验研究

Study of CIK Cells Effect on Tumor Cells Proliferation , Apoptosis and Expressions of E-Cadherin , β 1-integrin in Peritoneal Metastasis Model for Human Gastric Carcinoma in Nude Mice

目的探讨E-钙粘素（E-cd）、α-连接素（α-cat）和β-连接素（β-cat）在子宫颈癌中的表达及其与生物学行为的关系。

Objective To investigate Expression of E-cadherin , a-catenin and β - catenin in human cervical cancer and its relationship with the biological bahavior .

目的研究E-钙粘素介导的细胞粘附对卵巢癌细胞Akt及其上游的磷脂酰肌醇3-激酶（phosphatidylinositol3-Kinase，PI3K）信号的激活及对卵巢癌细胞增殖的作用。

Objective : To study the activation of Akt and its upstream molecule , phosphatidylinositol 3 kinase ( PI3K ) induced by E-cadherin-mediated cell-cell adhesion and their effect on ovarian cancer cell proliferation .

棉铃虫钙粘素基因的cDNA全长为5541bp（登录号：AY351904），具有5190bp的开放阅读框，编码1730个氨基酸的多肽。

The cDNA ( AY351904 ) of E-cadherin from larvae midgut of cotton bollworm had 5541 bp nucleotides with an open read frame of 5190 bp that encode 1730 amino acids .

目的：研究β-连接素（β-cat）和E-钙粘素（E-cd）在宫颈癌组织中的表达与其生物学行为的关系。

Objective : To investigate Expression of β - catenin (β - cat ) and E-cadherin ( E-cd ) in human cervical cancer and its relationship with the biological bahavior .

结论E-钙粘素激活卵巢癌细胞EGFR-PI3K-Akt相关的信号转导通路对肿瘤细胞的增殖有重要作用。

Conclusion : The activation on EGFR-PI3K-Akt cascade by E-cadherin mediated cell adhesion plays a major role in ovarian cell proliferation .

已有研究表明E-钙粘素（E-cadherin，E-cd）和β-连环素（beta-catenin，β-cat）与结肠直肠癌、黑色素瘤、肝细胞癌、卵巢癌及前列腺癌等多种肿瘤的发生发展及预后有关。

During recent years , many studies about E-cadherin and beta-catenin indicated that the oncogenesis and metastasis of many kinds of tumors such as colon tumor , melanin neoplasm , liver tumor , ovarian tumor and prostate tumor is related to E-cadherin and beta-catenin .

垂体腺瘤E-钙粘素和β-连环素的表达及意义

Expression and significance of E-cadherin and β - catenins in pituitary adenoma