整联蛋白
- 名integrin
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磷酯酰胆碱特异性磷脂酶C和膜整联蛋白β4调节血管内皮细胞凋亡信号通路的研究
Studies on the Apoptosis Signal Pathway Mediated by Phosphatidylcholine-Specific Phospholipase C and Integrin β _4 in Vascular Endothelial Cell
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FMDV受体猪源整联蛋白αvβ6单克隆抗体制备及分布的研究
Study on Monoclonal Antibody Preparation and Tissue Profile of Porcine Integrin α v β 6 as FMDV Receptor
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整联蛋白是一类主要的将细胞黏附到ECM的细胞表面受体,通过细胞骨架组织细胞形状,它们也影响细胞命运的决定。
Integrin is a major cell surface receptor adhering cell to ECM , cell shape was organized by cytoskeleton , they also affect cell fate decisions .
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FAK在整联蛋白介导的细胞粘附到细胞外基质的信号调节中起重要作用。
FAK has been implicated in playing an important role in signal transduction pathways regulated by integrin-mediated cell adhesion to ECM .
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结论:RGD肽作为αv整联蛋白的一种拮抗剂,不仅具有药物、基因治疗载体的导向运输功能,更具有肿瘤的直接杀伤效应,是一种理想的肿瘤靶向性治疗药物。
Conclusion : RGD peptide as an Alpha ( v ) integrin antagonist has not only targeted drug delivering function but also direct tumor-killing effects . RGD peptide is an ideal therapeutic agent for potential tumor targeting therapy .
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周期性应变诱导人肺上皮细胞整联蛋白再分布的研究
Cyclic Strain Induces Reorganization of Integrins in Human Pulmonary Epithelial Cells
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口蹄疫病毒受体羊源整联蛋白β6亚基配体结合域的原核表达、纯化及鉴定
Prokaryotic Expression , Purification and Identification of Ligand Binding Domain of Ovine Integrin β 6 as FMDV Receptor
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口蹄疫病毒受体猪源整联蛋白β6亚基配体结合域单克隆抗体识别的抗原表位分析
Analysis of Antigenic Epitopes Recognized by Monoclonal Antibody against Porcine Integrin β 6 Subunit LBD as FMDV Receptor
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输卵管闭锁和积水患者的子宫内膜α1和β3细胞整联蛋白亚单位的表达
Expression of alpha 1 and beta 3 integrins subunits in the endometrium of patients with tubal phimosis or hydrosalpinx
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这些受体中的一个被认为是b1-整联蛋白,该蛋白在许多肿瘤如转移性乳腺癌中能频繁的形成。
One of these receptors is what is known as b1-integrin , which is frequently formed in many tumors such as metastasizing breast cancer .
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氨基核苷嘌呤霉素诱导肾病变是人原发性肾病综合症的模型,抑制培养的肾小球上皮细胞整联蛋白的表达。
Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome , suppressing expression of integrin expression in cultured glomerular epithelial cells .