闭经

闭经发生率与年龄、化疗药物强度和化疗进程呈正相关（P均0.05）。

There was a positive correlation between the frequency of amenorrhea and the patients age , potency of chemotherapeutic drug and duration of chemotherapy ( P 0.05 ) .

测定血清FSH、LH、催乳激素、雌二醇与孕酮对继发闭经的诊断意义

Evaluation of serum fsh , lh , prolactin , estradiol and progesterone in diagnosis of secondary amenorrhea

方法对37例原发闭经患者进行外周血淋巴细胞染色体G显带分析。

Methods The chromosomal G banded karyotypes of 37 cases with primary amenorrhea were analyzed .

结果显示：POF组的B细胞数为19.16%，原发性闭经组为21.18%，均显著高于正常组的14.83%。

The B cell in POF group was 19.16 % , significantly higher than 14.83 % in normal group .

结论绝经前切除卵巢或过早的闭经易导致骨质疏松，即妇女绝经后骨质疏松与雌激素下降有显著关系（P＜0.001）。

Conclusions Ovariotomy before menopause or previous menoschesis will cause osteoporosis . Essentially , the falling level of estrogen in women is significantly related to osteoporosis . ( P < 0.001 ) .

原发性闭经患者染色体核型分析及SRY基因检测

Karyotype analysis and detection of SRY gene of primary menopause patients

本研究用40只Wistar大白鼠制作运动性闭经某些性激素分泌特点的动物模型。

Animal model of secretion characteristics of some sexual hormones in sport amenorrhoea was established with 40 Wistar rats .

动脉导管未闭经导管封堵术后Tei指数的变化

The change of Tei index after transcatheter closure of patent ductus arteriosus

目的了解高促卵泡激素（FSH）卵巢性闭经患者低骨量的特点。

Objective To observe the characteristics of low bone mass in amenorrhea with elevated follicle stimulating hormene ( FSH ) .

UAE还可引起少数妇女闭经，其原因与卵巢功能受损和子宫内膜萎缩有关。

UAE may cause amenorrhea in the minority of women with ovarian failure and endometrium atrophy .

罕见的46，X，inv（Xq）伴原发闭经一例

A Case of Rare 46 , X , inv ( Xq ) Concomitant with Primary Amenorrhea

月经紊乱组及闭经组P和E2低于正常对照组黄体期，相当于正常对照组卵泡期低水平。

The P and E2 level in abnormal menstruation and amenorrhea groups , was similar to that in the control group in follicular phase , but lower in luteal phase .

GnRH和HMG脉冲给药对下丘脑性闭经患者诱发排卵的临床疗效观察

Clinical study on ovulation induction by pulsatile administration of GnRH and HMG in women with hypothalamic amenorrhea

观察哺乳闭经避孕法（LAM）中不同喂养方式对产后闭经时间和妊娠率的影响。

Objective : To observe the effect of different feeding manner of LAM on postnatal contraception rate and amenorrhea period .

目的探讨继发性高促性腺激素闭经（SHA）的病因与表现的异质性（多样性）以及治疗对策。

Objective : To investigate the heterogeneity of clinical feature and etiology in patients with secondary hypergonadotropic amenorrhea ( SHA ) .

本文总结了3年来101例原发闭经的细胞遗传学研究，46，XX共60例，占59.4%；

This paper presents a cytogenetic study on 101 cases of primary amenorrhea , 60 cases ( 59.4 % ) were 46 , XX ;

空腹尿Ca/Cr值可作为预测闭经妇女BMC减低倾向的指标。

The fasting urinary calcium to creatinine ratio is an index for predicting the predisposition to osteopenia in amenorrheic women .

一例原发闭经46，X，psudic（X）（p22.3：：p22.3）

A Case of Primary Amenorrhea with 46 , X , psu dic ( X ) ( p22,3 : : p22.3 )

结果不孕症和闭经患者PRL极显著高于健康育龄妇女（P<0.01）；

Results The levels of PRL were significantly different between patients with sterility and menoschesis and health women ( P < 0.01 ) .

结果71例原发性闭经患者中检出核型异常者23例；6例SRY阳性。

Results : Among 71 cases of primary menopause abnormal karyotype was detected in 23 cases and SRY positive expression , in 6 cases .

本文介绍261例垂体腺瘤、52例鞍部其他肿瘤、67例原因不明闭经妇女血清催乳素（PRL）测定结果。

Serum prolactin ( PRL ) levels were studied in 261 patients with pituitary adenomas , 52 patients with other sellar-tumors and 76 patients with amenorrhea .

继发闭经组胰岛素拮抗指数和BMI显著高于月经规律组（P<005）。

In addition , between the groups of secondary amenorrhea and regular menstruation , insulin resistant index and body mass index were significantly higher in the former ( P < 0.05 ) .

受月经失调或闭经，或者不孕折磨的女性可能患有多囊卵巢综合症（PCOS）。

Females who are plagued with irregular or no menstrual cycles or who have problems becoming pregnant may have what is known as Polycystic Ovarian Syndrome ( PCOS ) .

并从闭经患者检查染色体的意义、Turner's综合征的细胞遗传学病因、核型46，XY的闭经患者的表型分析及常染色体畸变与闭经的关系等方面加以讨论。

The cytogenetic mechanism of the patients with amenorrhea and the phenotypic analysis of the patients with sex differentiation of 46 , XY karyotype were also discussed .

Logistic回归模型分析显示：闭经（OR3，P0.05）和未防晒（OR1，P0.05）与面部皱纹有关。

Analysis of Logistic Regression Model showed that there were correlations between facial wrinkle and menopause ( OR3 , P0.05 ) and no sunscreen products using ( OR1 , P0.05 ) .

结论在青春期表现有月经稀发和继发闭经的PCOS患者在育龄期有更严重的分泌代谢失调、并伴有较低的妊娠率。

Conclusion The reproductive patients with PCOS who had oligomenorrhea and secondary amenorrhoea in puberty have more severe endocrinal disorders , such as hyperandrogenism and insulin resistant with lower fertility .

目的分析原发性闭经患者染色体异常核型及Y染色体上的性别决定区（SRY）基因，并对原发性闭经的原因进行探讨。

Aim : To analyze the karyotype and detect the SRY gene of primary menopause patients so as to provide information for exploring the mechanism of primary menopause .

方法：因闭经或淋漓出血行诊刮内膜活检的PCOS患者34例作为研究组，选择同期就诊的月经规律，因不孕（非排卵障碍）或卵巢良性肿瘤行诊刮患者30例为对照组。

Methods : 34 PCOS patients served as study group , 30 patients with infertility or benign ovary tumer selected as control group , diagnostic curettage were preformed when they were seeking medical advice .

第一组6例（包括Sheehan综合征2例；继发闭经2例；无排卵1例；溢乳-闭经综合征1例）。

Group I included 6 cases , 2 each of Sheehan syndrome and secondary amenorrhea , and one each of anovulation and Galactorrhea-Amenorrhea syndrome .

DMPA主要副作用为阴道点滴状出血或突破性出血、排卵恢复延迟及体重增加，随用药时间延长闭经增加。

The main side effects of DMPA were irregular bleeding or spotting , delaying of ovulation and weight gaining . A long-term use of DMPA typically results in amenorrhea .