颅内感染

随机扩增多态DNA指纹图技术对颅内感染病原菌的研究

A study of intracranial infection pathogenic bacteria using random amplify polymorphic DNA fingerprint technology

颅内感染时，炎性细胞或血小板等均可产生血管内皮生长因子（VascularEndothelialGrowthFactor，VEGF），破坏血脑屏障，加重脑水肿。

In intracranial infection , inflammatory cells or platelet can generate vascular endothelial growth factor ( VEGF ), which break blood-brain barrier and cause cerebral edema .

脑脊液IL-2、TNF-α在儿童颅内感染鉴别诊断中的意义

Differential diagnostic significance of interleukin-2 and tumor necrosis factor - α in cerebrospinal fluid of children with acute central nervous system infections

颅内感染患儿血清和脑脊液中SIL-2R、NSE的改变及临床意义

Clinical Significance of the Changes of SIL-2R 、 NSE in Serum and Cerebrospinal Fluid in Children with Intracranial Infection

前言：目的：探讨颅内感染患者脑脊液中一氧化氮（NO）及一氧化氮合成酶（NOS）含量改变的临床意义。

Objective : To investigate the alteration of NO and NOS contents in cerebrospinal fluid of patients with intracranial infection and its clinical significance .

方法：应用相应试剂盒对40例颅内感染患者和15例非感染者（对照组）脑脊液（CSF）中的NO及NOS进行测定。

Methods : The contents of NO and NOS in40 patients CSF and15 controls CSF were determined according to the instructive manual attached to respective kit .

结果持续腰池脑脊液引流治疗SAH的治愈率为100%，无颅内感染、气颅及脑疝等严重并发症。

Results Successful treatment was achieved in 100 % and there was no occurrence of intracranial infection or pneumocephalus and brain herniation .

目的探讨SIL-2R、NSE在颅内感染中的改变及临床意义。

Objective : To study the clinical significance of the changes of CNS SIL-2R 、 NSE in children having central nervous system infection ( CNSI ) .

目的探讨颅内感染（ICI）患者脑膜刺激征（MIS）阴性的相关因素及其机理和临床意义。

Objective To explore the associated factors , its mechanism and clinical significance of negative meningeal irritation sign ( MIS ) in patients with the intracranial infection ( ICI ) .

新生儿败血症最常合并呼吸道感染，其次是皮肤粘膜感染与颅内感染，两组之间在消化道、颅内、皮肤和泌尿系的感染率有显著差异（P0.05）。

The most common complication is respiratory tract infections , then skin infections and intracranial infections . There are significant difference in infection rates among GI tract , CNS , skin and urinary system ( P0.05 ) .

方法对42例颅内感染患者128次腰穿和45例脑出血患者138次腰穿测压前均行TCD检查并记录血压。

Methods TCD examination was carried out before lumbar puncture for pressure testing in 42 intracranial infection patients ( 128 times ) and 45 ICH patients ( 138 times ) .

目的探讨常见颅内感染患者脑脊液中磷脂酶A2（PLA2）活性变化及其临床意义。

Objective To investigate the changes of the phospholipase A2 ( PLA2 ) activity in cerebrospinal fluid ( CSF ) of common intracranial infected patients and its clinical significance .

结论TNF-α、IL-1β、IL-6在颅内感染中起重要作用，对颅内感染的诊断和鉴别诊断有重要意义。

Conclusion It is suggested that the levels of TNF - α, IL-1 β and IL-6 may play an important role in the pathogenesis of intracranial infections and may serve as a marker for diagnosis and differential diagnosis .

羊瘙痒病小鼠适应株139A可突破种属屏障颅内感染金黄地鼠

Mouse-adapted Scrapie Strain 139A Can Overcome Species Barrier to Induce Spongiform Encephalopathy in Golden Hamster

但脑内直接注射VEGF需反复给药、价格昂贵、易造成颅内感染，直接应用携带VEGF基因的质粒存在表达不足，而腺病毒又存在安全隐患问题。

However , there are still a lot of unsolved problems so far , for example , requirement of repeating injections of VEGF into the brain , very expensive cost , intracranial infectibility , insufficient expression of VEGF plasmid , and unsafely of adenovirus .

应用聚合酶链反应（PCR）检测技术对118例颅内感染性疾病患者及37例无神神经系统疾病患者脑脊液（CSF）中的单纯疱疹病毒DNA（HSV－DNA）进行了检测及分型。

This article presents the direct detection and typing of herpes simplex virus DNA ( HSV-DNA ) in cerebrospinal fluid ( CSF ) of 118 intracranial infectious cases and other 37 cases without any intracranial disease by means of the ploymerase chain reaction ( PCR ) .

结果：脑瘫常见病因中窒息占36%，早产15%，缺氧缺血性脑病（HIE）15%，颅内感染10%，其他病因均较少。

RESULTS : The most common pathogenic factors of CP were apnea ( 36 % ), premature birth ( 15 % ), hypoxic ischemic encephalopathy ( HIE )( 15 % ) and infection in cranium ( 10 % );

临床上一小部分FS患儿实际上可能存在中枢神经系统病毒感染，必要时应腰穿检查，以区别人为界定的热性惊厥与颅内感染。

In clinical practices , there may be a small part of FS patients involved in CNS infections . It is essential to perform a lumber puncture and a CSF test to differentiate intracranial infections from FS when necessarily .

结论对颅脑外伤病人进行CT检查时，增加颅底薄层高分辨扫描及MPR，能提高颅底骨折的检出率，减少漏诊。对临床硬脑膜修补的筛选、预防颅内感染具有重要的指导意义。

Conclusion When cranial trauma patients are proceeding CT scan , adding thin-section HRCT scanning and MPR can increase the finding rate of basal skull fractures and reduce leak-diagnosis , which have an important guide significance for clinic selection of patients for dural repair and preventing from intracranial infection .

结果脑脊液漏5例，颅内感染2例，术后17d鼻腔大出血1例。

Results CSF leak occurred postoperatively in 5 cases , intracranial infection occurred in 2 cases , serious nasal bleeding occurred in 1 case 17 days after operation .

目的观察经颅多普勒（TCD）频谱参数在颅内感染和脑出血患者初期颅高压的相关变化，进而预测颅内压（ICP）和脑灌注压（CPP）并比较TCD预测的准确性。

Objective To observe the spectra and parameter changes of transcranial Doppler ( TCD ) in early stage of intracranial hypertension of intracranial infection and intracerebral hemorrhage ( ICH ) to predict the intracranial pressure ( ICP ) and cerebral perfusion pressure ( CCP ) .

结果：4例中有3例主诉视力障碍，1例有明显颅内感染征象，2例出现垂体功能低下，病理检查证实1例为Rathke裂囊肿合并感染，另3例感染机制不明。

Results : Before operation , visual disturbance was present in 3 cases , hypopituitarism in 2 and meningitis in 1 . Abscess formation in Rathkes cleft cyst was confirmed by pathology in one case . Good results were achieved with surgical resection in all cases .

阿米卡星鞘内注射治疗开颅术后颅内感染的应用研究

Intracranial infections after craniotomy treated with intrathecal Amikacin : clinical study

神经外科术后颅内感染相关因素分析与预防对策

Risk Factors and Preventive Therapeutic Strategies on Intracranial Infection after Craniotomy

18例严重颅内感染患者治愈17例；

Of 18 patients with intracranial suppuration , 17 were cured ;

万古霉素不同给药途径预防脑外伤颅内感染研究

The investigation of different antibiotics administration routes to prevent intracranial infection

影响颅脑外伤术后颅内感染的危险因素分析

Analysis of risk factors of affecting intracranial infection complicating brain injury operation

改良式腰大池置管持续外引流治疗术后颅内感染

Treatment of Postoperative Intracranial Infection by Reforming-Continuous Lumbar Subarachnoid Drainage

无死亡、再出血及颅内感染。

No death , rebleeding and intracranial infection occurred postoperatively .

脑室内复达欣灌注治疗颅内感染

Treatment of Encephalic Infection by Perfusing Fu Daxin into Ventricles of Brain