骨外膜

17β-雌二醇对骨外膜来源骨原细胞作用的研究

Study of the Effects of 17 β - estradiol on Osteoprogenitors from Periosteum

牵引完成后12周，除骨髓腔中纤维血管基质可见少量TGFβ1的阳性着色颗粒外，在骨外膜、骨基质及骨细胞内已见不到明显的TGFβ1的阳性着色。

Twelve weeks after distraction , positive stain of TGF β 1 could seldom be seen except in the marrow 's fibrous and vessel bases .

组织学：实验侧术后2周骨外膜成骨细胞增生活跃，骨折断端间纤维连接，并出现了软骨组织和新生骨小梁；

Histological findings in the experimental side included active proliferation of osteoblast in exterior periosteum , fibrous connection , cartilage and newly formed bone trabeculae between fragments of the fracture at the end of the 2nd week ;

对骨外膜与骨内膜的初始直径大小进行设置，最后结果表明在生长期内骨干骨外膜和骨内膜直径明显增大，表现出骨外膜向外扩展和骨内膜扩展后吸收。

For bone initial geometries , the periosteal and endosteal diameters are set , the results show that the periosteal and endosteal diameters can increased significantly after simulation , it is presented that periosteum expands outward and endosteal resorbs after expansion .

结论睾酮补充治疗短期内能对抗去睾丸引起的大鼠皮质骨内外膜的代谢变化，维持正常的皮质骨结构。

Conclusion Testosterone could keep the structure of cortical bone by accelerating periosteal bone formation and inhibiting endosteal bone resorption in ORX rats .

结果：在骨痂延长早期，骨外膜侧即有直接骨形成，而延长间隙中先形成纤维组织，以后逐渐向纤维骨痂、骨性骨痂演变，最终形成新生皮质骨。

Results : Direct osteogenesis occurred at the periosteal side in the early stage of distraction , whilst in the distraction gap , the fibrous tissue formed firstly and transformed to fibrous callus and bony callus gradually , resulting in the formation of new cortical bone ultimately .

与B组比较，C组大鼠胫骨上段的骨量增加（%Tb.Ar+79.8%，P<0.05），骨高转换率降低；胫骨中段皮质骨骨外膜的骨形成增加，骨内膜的骨吸收降低（P<0.05）。

Bone mass of PTM more improved ( % Tb . Ar + 79.8 % , P < 0.05 ) and higher bone turnover reduced in group C than in group B. Testosterone also could elevate periosteal formation and endosteal bone resorption .