骨痂

骨痂组织BMP含量高峰在第2～4周，用药组BMP含量高峰比对照组提前1周。

For the BMP content in the osteotylus tissue which reached its peak during the second through fourth weeks , it was one week earlier for the treated group to have BMP content peak than the control one .

失神经可致骨折局部形成大量有缺陷的骨痂。

Denervation can form lots of defective osteotylus around the fracture .

X射线平片检查测量骨痂直径。

The diameter of bone callus was measured by X-ray film .

结果CT观察到的骨痂生长早于X线平片，且更清楚。

Results CT is more clear than X-Ray .

结果：（1）伤后3d开始形成原始骨痂。

Results ( 1 ) Primary callus came into being 3 days after operation .

取胫骨，并于骨痂段行计算机断层扫描（CT），定量测定胫骨骨痂处骨灰度值；

Computed tomography scan ( CT ) was performed to measure gray values of callus quantitatively .

术后21天，各组均有骨痂形成，C组，D组骨折线变模糊。

After 21 days , callus formation in all groups , the fracture line blured in group C and D.

结果：1、骨痂组织形态学观察比较显示在各时相点B组，C组均优于A组。

According to the comparison of callus histology , it shows clear that both gourp B and group C are better than group A. 2 .

结果a组和b组4周开始形成骨痂，12周骨痂最丰富，24周复合材料与宿主骨边缘模糊，边缘部分的异体脱钙骨基质颗粒被新生骨替代，并与宿主骨融合。

Results In group a and group b , the callus was found at the 4th week postoperatively , abundant callus was found at the 12th week .

兔颅骨植入材料X射线片观察结果：X射线可见生物材料周围有明显骨痂形成，并随时间延长，骨痂越来越多。

X-ray observation results : There were obvious formation of callus around the biological material , which became much more as time went on .

方法利用SD大鼠骨质疏松胫骨骨折模型，测量了骨痂局部弹性模量和极限强度的变化。

METHODS The elastic modulus and maximum intensity in the local callus were measured using osteoporotic tibial fracture model .

分别于骨折后第8周，X射线观察各组大鼠骨痂生长以及骨折线的变化情况；

In the 8th week of fracture , the changes of fracture line and the growth of bony callus were monitored by X radioactive ray ;

结论冲击波能促进骨折愈合过程中VEGF、bFGF蛋白的表达，并能促进骨痂生成，加速骨折愈合。

Conclusion Shock waves can up-regulate expressions of VEGF and bFGF so that they are beneficial to bone healing .

应用RT-PCR和Western-blot法测定骨痂内的vEGFmRNA及VEGF蛋白的表达。

RT-PCR and Western blot were used to investigate the mRNA and protein expression of VEGF in bone callus .

骨折合并脑外伤患者骨痂中PDGF及NGF含量分析

Analysis of Callus NGF and PDGF Levels in Bone Fracture Affiliating Cerebral Trauma Patients

马钱子散对实验性骨折愈合骨痂局部BMP定量表达的影响

The Effect of Nuxvomica Powder on Local Content of BMP Expression during Experimental Fraction Healing

术后40天，C组，D组骨折处大量骨痂形成，局部增粗，骨密度增高，其余各组骨折线均已变模糊。

After 40 days , there were ponderosus callus formation in bone fracture of group C and D , partly thickening , bone density , the fracture line lured in other groups .

原始骨痂成骨细胞、骨端骨细胞和软骨细胞表达BMP。

Osteoblasts in the primary callus , bone cells in fracture ends and chondrocytes expressed BMP .

3增加TGF-β1在骨痂组织中的表达，促进骨折愈合弱CO2激光与红外线照射促进骨折愈合作用的比较研究

The augment of the expression of TGF β 1 . Comparative study of low level CO_2 laser and infrared ray irradiation on improving bone fracture healing process

组织学检测显示微动组骨痂软骨内骨化与类骨质形成的速率在6周最为明显，均快于对照组，以B组形成速率最快。

Histological analysis showed faster endochondral ossification and osteoid formation in the experimental groups than in the control by the sixth postoperative week , with the highest rate in Group B ( 1Hz ) .

结论桃红四物汤通过提高骨折后骨痂内VEGF的表达，加速断端微血管新生重建，促进骨折愈合。

Conclusion THSWD could improve the VEGF expression of callus tissue , accelerate the micrangium regeneration in bone stump and promote the healing of fracture .

X射线片显示直接接触辐射组、近场辐射组骨痂生成较对照组提前14d。

Compared with control group , the formation of bony callus in radiation groups advanced 14 days by X rays .

两侧兔桡骨缺损处X射线观察：在第12周实验侧有连续骨痂通过骨缺损处，髓腔通畅，塑形不完全。

X-ray scanning : At week 12 , callus was found continuously crossing through the bone defect of experimental side , marrow cavity was smooth , but molding was incomplete .

于骨折后4,7,14,21d收集骨痂样本，反转录聚合酶链反应测定诱导型一氧化氮合酶的mRNA表达水平。

The specimens of bony calluses were collected at 4,7,14 , and 21 days after fracture to detect the level of iNOS mRNA expression by reverse transcription-polymerase chain reaction .

骨质疏松性骨折骨痂软骨细胞增殖和IGF-I表达的实验研究

Experimental study of proliferation of chondrocyte and expression of IGF-I in the osteoporotic fracture callus

结果A组在X线表现、骨痂形成面积、三点弯曲破坏负荷、新骨形成率及骨孔隙率等方面均优于B、C、D组，与E组相仿。

Results Like Group E , Group A excelled Group B , C and D in the performance of X-ray , callus formation , maximal bending load , new bone formation rate and bone porosity .

自体晚期骨痂与BMP-7移植治疗骨缺损

Late-stage Bone Callus Implant Combine with BMP-7 on Healing Bone Defect

结果单纯骨折组表现为典型的骨折愈合过程，骨痂内纤维母细胞及成骨细胞内NGF阳性表达相对较弱。

Results The animal models in simple fracture group appeared a typical healing course , NGF expressed weakly in fibroblast and chondroblasts in callus .

术后7、14、28d分批处死动物，大体体积测量骨痂，X线片评分，并做HE染色比较。

The animals were sacrificed at 7 , 14 , and 28 days after surgery .

目的：探讨骨质疏松性骨折愈合过程中胞内信号因子CD44及其配体FN在骨痂软骨细胞的表达情况。

Objective : To study the expression of CD44 , FN of callus cartilage cell in the healing process of osteoporosis fracture .