分泌途径

这些数据显示VWF被分类来调节内皮细胞的分泌途径方式比先前报道的更为有效。

These data suggest that VWF is sorted to the regulated secretory pathway in endothelial cells much more efficiently than previously reported .

酵母蛋白分泌途径的研究进展

Advance in Secretory Pathway of Yeast

MSCs可能通过旁分泌途径诱导HSCs凋亡。

MSCs may induce apoptosis of HSCs through the paracrine pathways .

本研究首次探讨Sec分泌途径在变形链球菌蛋白分泌过程中的作用，同时结合生物膜形成过程重点研究变链菌毒力因子分泌的变化。

In our research , we firstly discuss whether S.mutans utilizes the general secretory ( Sec ) pathway to secret virulence factors and the changes of protein secretion in the process of biofilm formation .

以多发性肌炎（PM）、皮肌炎（DM）和包涵体肌炎（IBM）3个亚型最为多见。腺苷是细胞自分泌或旁分泌途径中的信号分子，在维持内环境稳定方面起重要作用。

The most prevalent subtypes are multiple polymyositis ( PM ), dermatomyositis ( DM ) and inclusion body myositis ( IBM ) . The adenosine is the signaling molecule of autocrine or paracrine pathway , and plays an important role in maintaining the internal environment stability .

调节性蛋白和结构性蛋白分泌途径的不同第一眼看过去就很明了。

The distinction between regulated and constitutive protein secretion pathways at first blush appears obvious .

非经典的蛋白质分泌途径

Non - classical Secretory Pathway

真核细胞的内吞和分泌途径中蛋白质和脂类的运输主要由膜泡运输介导。

The transport of proteins and lipids between eukaryotic cells via endocytosis and secretion is mainly facilitated by vesicular trafficking .

脂肪组织是乳腺不可缺少的组成部分，它在乳腺中不仅起着结构支架作用，还能通过旁分泌途径影响乳腺实质的发育，乳腺实质也能合成、分泌生长因子影响脂肪组织的变化。

Adipose tissue as a necessary part of the mammary gland promoted the mammary essential tissue development by paracrine not only supporting the mammary gland structure .

而利用基因打靶技术研究蛋白分泌途径的重要基因的功能有利于了解纤维素酶分泌输出的机制。

And , application of gene targeting to study the important genes involved in the protein secretion will contribute to understanding of the mechanism of cellulase transportation .

总之，我们的研究发现，在性激素作用下通过旁分泌途径前列腺外周带基质细胞具有更强的促前列腺癌发生发展的能力。

In conclusion , our data suggest that PZsc may have a greater capacity to induce PCa development and progression than TZsc via growth factors regulated by sex hormones .

囊泡转运和融合过程作为细胞生长繁殖的基本特征之一，在蛋白上膜及分泌途径中发挥重要的功能。

The process of vesicle translocation and fusion , as a ubiquitous and fundamental event in the cell growth and propagation , play a critical role in proteins trafficking and secretion .

分泌途径主要由内膜系统构成，内质网和高尔基体对于分泌蛋白的运输及定位具有重要作用。

The secretory pathway of eukaryotic organelles mainly consists of endomembrane system . The endoplasmic reticulum ( ER ) and the Golgi apparatus are the key organelles for the secretory protein transport and localization .

研究人员推测，其他所谓的裸病毒或无包膜病毒（比如最近困扰美国及亚洲儿童的感冒病毒和肠道病毒）同样能够通过非传统分泌途径传播。

The researchers suspect that other so-called naked or nonenveloped viruses ( like the cold virus and the enteroviruses that have lately plagued children in this country and Asia ) could likewise spread through unconventional secretion pathways .

研究目的：对比研究小型猪、小鼠的腮腺、颌下腺、舌下腺与泪腺、垂体的超微结构，为涎腺的基因转导治疗蛋白质分泌途径提供超微病理依据。

Objective : To perform comparative ultrastructural study of parotid glands , submandibular glands , sublingual gland , lacrimal glands , pituitary between minipig and mouse for providing ultrastructural basis for secretary pathway of gene transfer to salivary glands .

主要集中在分泌途径上，是分泌型蛋白且第1&26位氨基酸序列是一段信号肽，26与27之间存在一个酶切位点。

Mainly concentrated in the secretion of ways , the mitochondria in the small , is secreted protein and 1-26 in the first amino acid sequence is a signal peptide , between 26 and 27 there is a restriction site .

在多定位中，质膜和内质网共定位蛋白质所占的比例最大（215个，24.68%），其中主要是参与分泌途径的蛋白质分子，体现了肝脏旺盛的分泌能力。

Except the single localization , the plasma membrane and endoplasmic reticulum-targeted proteins had the largest proportion ( 215 , 24.68 % ) . Those protiens were mainly involved in the protein secretory pathway , which reflect the strong secretion function of the liver .

结论：复方中药降低CCl4诱导的HSCET-1水平及增加HSC分泌NO途径而抑制HSC的收缩。

CONCLUSION : Herbal compound decreased ET-1 level and increased NO secretion in HSC stimulated by CCl_4 to restrain HSC contraction .

氧化苦参碱对大鼠肝星状细胞旁分泌活化途径的抑制作用

The inhibition effect of oxymatrine on the activation of paracrine pathway of hepatic stellate cells

目的观察不同浓度的同型半胱氨酸（Hcy）对血管内皮细胞表达和分泌组织因子途径抑制物（TFPI）的影响。

Objective The aim of this study was to elucidate the effects of homocysteine ( Hcy ) on the expression and secretion of tissue factor pathway inhibitor ( TFPI ) in endothelial cells ( Ecs ) .

胰岛多肽激素分泌形式和转运途径与2型糖尿病关系的新探索

New Discoverings on the Secretory form and Transporting Route of Polypeptide Hormones of Pancreatic Islets and Its Relationship to Type 2 Diabetes Mellitus

Ⅱ型分泌系统主要以分泌途径转膜蛋白（GSP）基因簇为中心。

The probable general secretory pathway transmembrane protein ( GSP ) gene cluster is the center of the type II secretory system .

RT-PCR、免疫细胞荧光染色方法证实人胃成纤维细胞自身分泌CTGF，这表明CTGF通过自分泌、旁分泌途径发挥作用，为进一步研究CTGF与人胃成纤维细胞的关系提供了实验基础。

The results of RT-PCR and Immunocyte fluorescent staining prove that human gastric fibroblast itself secretes CTGF , which shows that CTGF takes into effect through the autocrine and paracrine manners . That provides experimental basis for further research on the relation between CTGF and human gastric fibroblast . 3 .

颗粒细胞是卵巢中十分重要的体细胞，其在发育的不同阶段合成和分泌激素以及多种生长因子，并通过自分泌或旁分泌途径发挥作用。

Granulosa cells play important role in the different development stages of ovarian by synthesizing and secreting a variety of hormones and growth factors through autocrine / paracrine .