外向电流

  • 网络outward current;Ito;STOCs
外向电流外向电流
  1. 以上结果显示该外向电流为延迟整流钾电流。

    All these characteristics indicated that the outward current was delayed rectifier potassium current .

  2. 甘氨酸激发的外向电流可被士的宁完全阻断。

    Glycine ( Gly ) induced an outward current which was completely abolished by strychnine .

  3. Ito电流是复极化早期重要的外向电流。

    Transient outward current ( Ito ) is an important ion current responsible for early repolarization of atria .

  4. 外向电流因此能增加细胞内的负电性。

    Outward currents therefore increase electronegativity in the cell interior .

  5. 大鼠海马锥体神经元外向电流特征分析

    Analysis on the Characteristic of outward Currents in Hippocampal Pyramidal Neurons of Rats

  6. 采用膜片钳技术以全细胞方式在鼠脑微血管内皮细胞中记录到一种延迟外向电流。

    Using the whole-cell patch-clamp technique , delayed outward currents are recorded in rat brain microvascular endothelial cells .

  7. 谷氨酸对大鼠海马CA1区神经元的短暂性外向K~+电流的影响

    Effects of glutamate on transient outward potassium current of

  8. 结论低氧时外向钾电流明显增加,它来源于KATP通道的开放。

    CONCLUSION Outward K + currents elevated significantly and come from K ATP channel during hypoxia .

  9. 左室功能减退窦性心律患者心房肌短暂外向钾电流mRNA表达的变化

    Alterations of mRNA Expression of Transient Outward K Current in Atria of Patients With Sinus Rhythm and Decreased Left Ventricular Function

  10. 目的探讨人右心室复极1相瞬间外向钾电流(Ito)的跨壁电不均一性。

    Objective To investigate the transmural electrophysiological heterogeneity of transient outward potassium current ( I_ to ) in repolarization phase 1 of the human right ventricle .

  11. 全细胞膜片钳(whole-cellpatchclamp)技术:胶原酶法新鲜分离单个家兔肠系膜阻力血管平滑肌细胞,全细胞电压钳制状态下监测应用目的药物Oxy前后外向钾电流&钙敏感钾通道的电流变化。

    Whole-cell patch clamping : Whole cell currents were recorded in freshly isolated rabbit mesentery artery smooth muscle cells via the whole-cell patch clamp technique .

  12. 观察心房颤动(AF)心房肌细胞的电生理特点,探讨短暂外向钾电流(Ito)与AF电重构的关系。

    The aim of this research was to elucidate the relation between transient outward potassium current ( I to ) and electrical remodeling in atrial fibrillation ( AF ) .

  13. 目的:观察血清素(5-HT)对大鼠心室肌细胞瞬时外向钾电流I(to)的影响并探讨其作用机制。

    AIM : To study the effects of serotonin ( 5-hydroxy-tryptamine , 5-HT ) on transient outward potassium current ( Ito ) and elucidate its mechanism in rat ventricular myo-cytes .

  14. Cyclopiazonicacid增加SHR和WKY血管平滑肌细胞Ca~(2+)-依赖性外向K~+-电流

    Cyclopiazonic acid enhanced the Ca ~ ( 2 + ) - dependent outward K ~ + currents in cultural aortic smooth muscle cells from SHR and WKY

  15. AT1细胞上的一种重要外向钾电流是快速激活型迟缓整流外向钾电流(IKr)。

    An important outward potassium current in AT-1 cells is the rapidly - activating delayed rectifier ( I Kr ) .

  16. 目的:研究未成年人心房肌细胞瞬间外向钾电流(I(to))和内向整流钾电流(I(Kl))的特性。

    AIM : To study the properties of transient outward K + current ( Ito ) and inward rectifier K + current ( IK1 ) in immature human heart .

  17. 提示Lien有钠、L型钙通道阻滞作用并抑制稳态外向K+电流,这些可解释Lien广泛的抗心律失常作用机制。

    The results suggested Lien has blocking actions on sodium and calcium channels and could inhibit steady-state outward K + currents , which can explain the mechanism of extensive antiarrhythmic actions of Lien .

  18. 蝎毒素BmkTXKβ对家兔心房肌细胞瞬间外向钾电流的抑制作用

    Inhibitory Effect of BmkTXK β on Transient Outward Potassium Current in Rabbit Atrial Myocytes

  19. 目的探讨咪达普利对陈旧性心肌梗死非梗死区心肌跨室壁复极离散度(TDR)以及短暂外向钾电流(Ito)的影响。

    Objective The aim of this study is to investigate the effects of imidapril on transmural dispersion of repolarization and heterogeneous changes of transient outward potassium current in the region remote from the infarction area three months after myocardial infarction .

  20. 目的研究慢性孵育β淀粉样肽(25-35)(βAP25-35)对海马神经元上瞬时外向钾电流(IA)和延迟整流钾电流(IK)的影响。

    AIM To investigate the effects of chronic exposure to beta amyloid peptide 25-35 (β AP 25-35 ) on transient outward ( I A ) and delayed rectifying ( I K ) current in cultured rat hippocampal neurons .

  21. 因而,该实验中,通过运用全细胞膜片钳的实验方法,我们发现gp120能显著引起外向钾电流的增高,且呈明显的浓度依赖性。

    Thus in the present study , the whole-cell patch clamp technique was performed and the data showed that gp120 significantly increased the amplitude of K ~ + currents in a dose-dependent manner .

  22. 结论:DHO可使Na+/K+泵兴奋,产生了外向泵电流。

    CONCLUSION : DHO could stimulate Na + / K + pump , and generate the outward pump current .

  23. 在某些心力衰竭患者中常观察到心肌细胞短暂外向钾电流(Ito)下降和动作电位时程(APD)延长,笔者主要探讨Ito下降与心肌肥大的关系及内在机制。

    Decreased transient outward potassium current ( Ito ) and prolonged action potential duration ( APD ) are commonly observed in some of heart diseases . The purpose of this study is to investigate the relations between reduction of Ito and myocardial hypertrophy and explore its mechanism .

  24. 利用全细胞膜片钳技术,在急性分离的大鼠海马锥形细胞上研究了La3+对快速激活与失活的瞬时外向钾电流IA和平台电流IK的影响。

    Using the whole cell patch-clamp technique , the effects of La ~ ( 3 + ) on transient outward K ~ ( + ) and delayed rectifier K ~ ( + ) currents kinetics were studied in acutely isolated rat hippocampal neurons .

  25. 方法:用酶消化法分离大鼠肝细胞,应用全细胞膜片钳技术,研究小檗碱对大鼠肝细胞延迟外向钾电流(IK)和钙释放激活钙电流(ICRAC)的影响。

    METHODS : Tight-seal whole-cell patch-clamp techniques were performed to investigate the effects of berberine on the delayed outward potassium currents ( IK ) and Ca2 + release-activated Ca2 + current ( ICRAC ) in enzymatically isolated rat hepatocytes .

  26. 异丙酚抑制大鼠心室肌细胞短暂外向钾电流

    Inhibition of transient outward potassium current in rat ventricular myocytes by propofol

  27. 去甲肾上腺素对大鼠肝细胞延迟外向钾电流的影响

    Effects of noradrenaline on delayed outward potassium current in isolated rat hepatocytes

  28. 瞬时外向钾电流及其调控因素的研究进展

    Progress in Transient Outward Potassium Current and Its Regulating Factors

  29. 心房颤动患者瞬间外向钾电流重构的分子基础

    Molecular basis of I_ ( to1 ) remodeling in patients with atrial fibrillation

  30. 心室肌M细胞瞬时外向钾电流特性研究

    The study of the characteristics of the transient outward current from ventricular in canine