核破

其中单核破骨细胞在第3天、多核破骨细胞在第5天时达到峰值。

Mononucleated osteoclast reached peak level at 3 days after tooth movement , while multinucleated cells reached peak level at 5 days .

结果多核破骨细胞数量呈双峰样改变，峰值分别为3月龄的113～132个/孔和16月龄的106～147个/孔；

Results The pattern of osteoclast number showed double-peak and the peak number was 113-132 per well in 3-month-old rats and 106-147 per well in 16-month-old rats for multinucleated cell .

1,25（OH）2维生素D3诱导大鼠骨髓单核细胞形成破骨细胞

1,25 ( OH ) _2 Dihydroxyvitamin D_3 Induces the Formation of Osteoclasts from Mononuclear Cells of Rat Marrow

用1,25（OH）2D3诱导骨髓单核细胞获得破骨细胞，并用抗酒石酸酸性磷酸酶（TRAP）染色进行鉴定。

Osteoclasts were generated by inducing bone marrow cells of SD male rat with 1,25 ( OH ) _2D_3 . Osteoclasts were identified through tartrate-resistant acid phosphatase ( TRAP ) staining .

脐血单核细胞向破骨细胞诱导分化的实验研究

Research of Osteoclast-like Cells Formed from Umbilical Cord Blood Cells

辛伐他汀对钛颗粒刺激人单核细胞形成破骨细胞的影响

Effect of simvastatin on inhibiting osteoclasts cytomorphosis from PBMC stimulated by Ti particles

骨髓和脾脏中单核细胞形成破骨细胞能力的对比研究

Comparison of the ability of forming osteoclasts of monocytes in bone marrow and spleen

破骨细胞是唯一具有骨吸收能力的多核细胞。破骨细胞来源于定向的髓系前体细胞。

The osteoclast is a unique bone-resorbing cell which contains multiple nuclei , derived from committed myeloid progenitors .

免疫组织化学染色检测该蛋白在病变中的破骨细胞以及单核细胞向破骨细胞分化过程中的表达。

Detect the expression of the protein in cherubism osteoclasts and the pre-osteoclast in the different stage of differentiation by immunohistochemistry .

Ⅰ型胶原mRNA定位于成骨细胞，而MMP－9则主要在破骨细胞、衬细胞和一些骨髓单核细胞（包括破骨细胞前体细胞）中表达。

Type 1 collagen mRNA located in osteoblasts , whereas MMP 9 was mainly expressed in osteoclasts , some lining cells on bone surface and some mononuclear cells in bone marrow , including mononuclear osteoclastic precursor cells .

结果显示，当培养细胞在RANKL和M-CSF联合作用下，TRAP阳性染色的单核和多核破骨细胞可在3天内迅速形成，骨片吸收实验显示骨片上出现典型的骨吸收征象；

The results show that when M-BMMs were further cultured with RANKL and M-CSF , TRAP-positive mononucleared and multinucleated cells were formed within 3 days , typical resorption lacunae were formed on bone slices .

本研究进一步证实了肿瘤性多核巨细胞可能与破骨细胞一样来源于同一前体细胞。

It further demonstrated that MGC and the osteoclasts might be derived from the same precursor cells .

压力与牙周膜细胞对体外诱导脐血单核细胞分化为破骨样细胞的影响

Effect of continuously compressive pressure and human periodontal ligament cells on the differentiation of osteoclast-like cells in vitro

成骨细胞和破骨细胞的传导通路和相关因子压力与牙周膜细胞对体外诱导脐血单核细胞分化为破骨样细胞的影响

The transduction pathway of osteoblasts and osteoclasts and related factors Effect of continuously compressive pressure and human periodontal ligament cells on the differentiation of osteoclast-like cells in vitro

目的观察1,25二羟维生素D31,25（OH）2D3诱导成年大鼠骨髓来源的单核细胞形成多核破骨细胞的作用。

Objective To investigate the effect of 1,25 ( OH ) 2 dihydroxyvitamin D3 on the generation of osteoclasts from mononuclear cells of adult rats .

破骨细胞是负责吸收骨质的多核巨细胞，主要来源于单核/巨噬细胞系，该细胞系RANK表达的多少在某种程度上体现了单核/巨噬细胞向破骨细胞样细胞分化的潜能。

Osteoclasts are a kind of multinucleated giant cell derived from monocyte / macrophages line , capable of bone absorption . The level of RANK expression in the cell line indicated the potential of monocyte / macrophages differentiating into osteoclast-like cells .