毛细胞再生

听觉损伤后毛细胞再生与聋病基因治疗策略

Strategies of inner ear hair cell regeneration and gene therapy for hearing loss

我们将涵盖有关于内耳发育与毛细胞再生的主题。

We will cover topics relating to inner ear development and hair cell regeneration .

EGF组毛细胞再生活跃，PCNA阳性细胞核明显增多。

In EGF group hair cell regenerated were active , and the number of PCNA positive cell nuclear increased obviously .

结论：提示c－myc基因表达是毛细胞再生过程中的一个重要分子事件，可能与前体细胞增殖有关。

Conclusion : The results indicate that c-mys gene expression may be an important molecular event in HC regeneration and may play a role in regulating progenitor cells proliferation .

结论Survivin参与小鼠内耳发育，在细胞增殖与分化、器官塑形过程中起一定的作用，为探索毛细胞再生和耳聋防治奠定基础。

Conclusion Survivin played an important role in the development of inner ears of mice , including the proliferation and differentiation of cells and the mold of organ . It laid a foundation of further study on the regeneration of hair cells and the prevention and treatment of deaf .

目的：建立大鼠耳蜗感觉上皮细胞（CSEC）的原代培养体系，为研究毛细胞再生的分子机制提供大量来源一致的细胞。

Objective : To further investigate the mechanisms of hair cell generation or regeneration , the primary culture systems of cochlear sensory epithelial cell ( CSEC ) of rats were established .

小鼠胚胎耳蜗辐射损伤后毛细胞再生及其机理的研究

Hair Cell Regeneration in the Mouse Embryonic Cochlea Damaged with Irradiation

研究者们还认定，毛细胞再生可以提高听力。

They also determined that hair-cell regeneration can result in improved hearing ;

内耳前庭毛细胞再生的实验研究

Experimental Studies on Regeneration of tbe Vestibular Cells

创伤后内耳毛细胞再生、修复和影响因素

Regeneration and repair of damaged hair cells in the inner ear and its controlling factors

高强纯音声损伤鸡耳蜗后毛细胞再生研究

Hair Cell Regeneration and Recovery Following Intense Sound Exposure Induced Damage in the Chick Cochlea

庆大霉素致损后鸡耳蜗毛细胞再生的放射自显影研究

Autoradiographic Study in the Regeneration of Hair Cells of the Chicken Cochlea Following Gentamycin Toxicity

用于毛细胞再生研究的噪声性聋动物模型的建立

A Model of NIHL guinea pig for study of cochlear hair cell regeneration in mammalian

促进毛细胞再生主要有两种办法。

There are two main approaches to efforts aimed at inducing hair cells to regenerate .

小鸡基底乳头毛细胞再生中增殖细胞的免疫组织化学染色显示

The method of detecting proliferating cell in the basilar papilla of chick during hair cell regeneration

鸡耳蜗结构的观察庆大霉素损害鸡耳蜗后毛细胞再生的超微结构及其与听功能恢复的关系

Ultrastructural observations on regenerating hair cells and functional recovery in the avian cochlea following gentamycin ototoxicity

创伤后的毛细胞再生提示有三种模式：支持细胞的再生性增殖；

Three modes of hair cell renewal following injury were suggested : regenerative proliferation of supporting cells ;

声损伤后鸡听觉上皮的修复和毛细胞再生&扫描电镜与图像分析研究

Restoration of auditory epithelia and regeneration of hair cell of chicks following acoustic TRAUMA-STUDY of SEM and image analysis

爆震和白噪声损伤后雏鸡耳蜗毛细胞再生及增殖细胞核抗原表达的研究

Study on hair cell regeneration and expression of PCNA in young chicken cochlea traumatized by blast and white noise

庆大霉素中毒后雏鸡耳蜗毛细胞再生和表皮生长因子的促再生作用

Hair cell regeneration in young chicken damaged by gentamicin and the effect of epidermal growth factor on promotion of regeneration

有一项研究发了然一种似乎可以让动物毛细胞再生的发育蛋白。

One finding identified a developmental protein that appears to be turned on in animals able to regenerate hair cells .

15年前，你的叔叔比尔是某位研究麻雀耳内毛细胞再生的著名学者的实验室里的高年级博士班学生。

15 years ago , your Uncle Bill was a senior graduate student in the lab of a famous researcher studying hair cell regeneration in sparrows .

他们的团队同时还在进行另一组研究，试图了解导致斑马鱼、鸟类和老鼠的毛细胞再生的基因和其他分子。

The teams also are working on a separate group of studies to understand the genes and other molecules that allow the regeneration of hair cells in zebrafish , birds and mice .

“如果我们理解了这种细胞的基因模板，那么我们就可以利用这个模板在哺乳动物身上模拟毛细胞再生，”他说。

' If we understand the template of genes that are expressed by the cells we would want to divide , then we could tap into that template'to mimic regeneration efforts in mammals , he says .

而华盛顿大学等组织的其他研究人员则将注意力集中在同毛细胞再生有关的分子和遗传学原理，以及如何在毛细胞无法再生的动物身上重复这一过程上面。

Other researchers , like those at the University of Washington , are focused on understanding the molecules and genetics involved with hair-cell regeneration , and how to mimic this process in animals that don 't spontaneously regenerate hair cells .

结论：GM耳中毒的雏鸡耳蜗毛细胞可以再生；

Conclusion : Hair cell may regenerate after GM damage .

当恢复1周后，受损处毛细胞迅速再生，至恢复2周后Bp基本正常。

By four weeks post recovery , the regeneration hair cell developed normal sensory hair cells .

目的：观察雏鸡庆大霉素（GM）中毒后耳蜗毛细胞的再生及表皮生长因子（EGF）对其再生的影响。

To observe hair cell regeneration and the effect of epidermal growth factor ( EGF ) in young chickens damaged by gentamicin ( GM ) .

庆大霉素中毒后小鸡耳蜗毛细胞的再生研究

Hair cell regeneration in the chick cochlea following gentamycin ototoxicity

庆大霉素损伤后的毛细胞可以再生。

Hair cells after gentamicin-induced cochlear damage possess regenerative ability .