烟曲霉

烟曲霉单克隆抗体的制备与鉴定以及烟曲霉GM抗原捕获方法的建立

Preparation and Characterization of Monoclonal Antibody of Aspergillus Fumigatus and Establishment of Aspergillus Fumigatus GM Antigen-capture Assay

烟曲霉几丁质合成酶基因chsC在烟曲霉的生长、形态和抗真菌药物敏感性方面起着重要的作用。

ChsC gene of Aspergillus fumigatus play an important role in its lifestyle , appearance and sensitivity for antifungus drugs .

肉桂醛和柠檬醛对黄曲霉及烟曲霉细胞DNA与RNA的影响

Effect of cinnamaldehyde and citral on DNA and RNA in Aspergillus flavus and A. fumigatus cells

毛霉、烟曲霉、念珠菌病石蜡切片各1例的PCR扩增结果均阴性。

Each 1 sample Mucor , Aspergillus fumigatus and albicans of PCR amplification is negative . 3 .

烟曲霉感染中Toll样受体作用机制研究进展

Advance in Study on Mechanism of Toll-like Receptor During the Infection of Aspergillus Fumigatus

一种快捷、定量检测烟曲霉GM抗原双mAb夹心ELISA的方法

Development of a rapid quantitative double mAb sandwich ELISA for detecting galactomannan antigen of aspergillus fumigatus

TNP-470是半合成的烟曲霉素类似物，具有较强的抗血管生成活性。

TNP-470 , a semisynthetic analogue of fumagillin has a potent antiangiogenesis effects .

目的：研究核苷酸结合寡聚化结构域（nucleotide-bindingoligomerizationdomain，NOD）相关蛋白在烟曲霉（Af）感染小鼠肺组织中的表达。

Objective : To study the expression of nucleotide-binding oligomerization domain ( NOD ) associated proteins in lungs of mice infected with Aspergillus fumigatus .

CMC固定化烟曲霉活菌体小球中微生物的增殖及基质消耗动力学长白山红蚂蚁微量生物活性物质分析

Multiplication and substance consuming kinetics of Aspergillus fumigatus entrapped in CMC Microanalysis of the Biologically Active Ingredients in Red Ant ( Formica Aquilonia ) in Changbai Mountains

目的研究O-（氯乙酰-氨甲酰基）烟曲霉醇（TNP-470）联合5-Fu对大鼠结肠癌肝转移生长的抑制作用。

Objective To study O - ( chloracetyl-carbamoyl ) aspergillus fumigatus cedrol ( TNP-470 ) united 5-Fu in inhibiting metastasis of rats ' colon cancer .

抗烟曲霉GM单克隆抗体用于烟曲霉感染免疫酶组织化学染色，具有快速、直观、清晰可见、结果容易判断的优点，为烟曲霉菌组织学检测增加了一种特异性的诊断手段。

GM McAb-HRP can be used as immunoenzyme histochemical stain in Aspergillus infection cases . It is a rapid , direct-viewing , results facility judgement , and develop a new and specific diagnosis method of Aspergillus fumigatus histology examination .

目的：为了验证O-烟曲霉醇（TNP-470）和丝裂霉素联用的增效作用。

Objective : To determine whether O - ( Chloroacetyl-carbamoyl ) - fumagillol ( TNP-470 ) could potentiate the anti-tumor effect of mitomycin .

为建立快速、简便、灵敏的检测烟曲霉震颤素B（fumitremorginB，FTB）的定量检测方法，利用自行制备的FTB制备出3种FTB复合抗原。

To find the quick , convenient and sensitive method for detecting quantitatively the fumitremorgin B ( FTB ), three complex antigens were produced .

目的研究烟曲霉醇（TNP-470）联合健择（Gem）对人肺腺癌细胞（A549）和人脐静脉内皮细胞（ECV-304）血管内皮生长因子（VEGF）及其受体FLT-1、KDR表达的抑制作用。

Objective To investigate the effect of TNP-470 and Gemcitabine ( Gem ) on the expression of VEGF , FLT-1 , KDR in human pulmonary adenocarcinoma A549 cells and umbilical vein endothelium ECV-304 cells .

考虑到几种镰刀菌真菌毒素增加的风险，在欧盟、美国、加拿大和其他国家确定了DON、ZEA和烟曲霉毒素的调节限量。

Taking into account the risk of increased occurrence of several Fusarium mycotoxins , regulatory limits of DON , ZEA and fumonisins were established in EU , USA , Canada and other countries .

将含烟草钙调蛋白信号肽序列的烟曲霉WY-2植酸酶基因组成型表达在烟草中。

The A.fumigatus WY-2 phytase gene fusing with the signal sequence from tobacco calreticulin was constitutively expressed in tobacco .

产烟曲霉酸等甾型抗生素的真菌，例如烟曲霉和金龟子绿僵菌等，具有优良的甾体羟化和C1,2位脱氢能力。

Aspergillus fumigatus and Metarhizium anisopliae , fungi which produce steroid antibiotics like helvolic acid , have a great capability for steroid hydroxylation and C1,2 dehydrogenation .

结论：RNAi在烟曲霉中的应用使快速敲除靶基因产生类似基因敲除的表型，为研究靶基因功能、识别可能的药物作用靶位奠定了良好的基础。

Conclusion : Silencing the investigated gene of A. fumigatus by RNAi will allow easier knockout a gene of interest to generate the phenotypic consequences of reducing expression of target gene , it settle a favourable foundation to research gene function and to identify potential target site of drug action .

烟曲霉产壳聚糖酶液体发酵条件研究

Study on conditions of chitosanase from Aspergillus fumigatus by liquid fermentation

对烟曲霉植酸酶的酶学特性进行了研究。

The enzymatic characteristics of phytase from Aspergillus fumigatus were studied .

很多分子和基因与烟曲霉的毒力相关。

Many molecular and genes involved the virulence of Aspergillus fumigatus .

磷脂酶D在烟曲霉中的作用还没有研究和报道。

There is poor study of phospholipase D in A. fumigatus .

五种抗深部真菌药物对烟曲霉体外抗菌活性的实验研究

In vitro activity study of five anti-deep fungal drugs against Aspergillus fumigatus

烟曲霉组氨酸激酶基因片段的隆及表达分析

Cloning and Expression of Histidine Kinase Gene of Aspergillus Fumigatus

胰蛋白酶对烟曲霉分生孢子表面纤连蛋白受体的影响

The effect of trypsin on surface fibronectin receptors of Aspergillus fumigatus conidia

固定化烟曲霉吸附染料后的解吸平衡及动力学研究

Desorption equilibrium and kinetics for dyes absorbed on immobilized inactive Aspergillus fumigatus

烟曲霉分生孢子表面形态改变及纤连蛋白受体分布状态

Change of Surface Shape and Distribution of Fibronectin Receptors on Aspergillus fumigatus Conidia

结论烟曲霉组氨酸激酶基因的表达可能有助于其在体内存活，该基因可能是烟曲霉潜在的毒力基因。

Conclusion The results indicate that this gene may attribute to the invasive aspergillosis .

侵袭性烟曲霉感染早期病原学诊断方法研究

Early Laboratory Diagnosis of Invasive Aspergillus Fumigatus Infection

烟曲霉醇联合5-氟尿嘧啶抑制大鼠结肠癌肝转移的实验研究

Experimental study of TNP-470 united 5-Fu in inhibiting metastasis of rats ' colon cancer