神经祖细胞

在调节神经元分化方面Bcl-xl和Bax起决定性作用，而Bax和Bak在调节神经祖细胞量方面起作用。

Bcl-xl and Bax play crucial roles in regulating neuron differentiation . Bax and Bak play roles in regulating the amount of the neural progenitor cell .

丹参酮ⅡA对神经祖细胞系C17.2的保护作用

Protective effect of Tanshinone ⅱ A on neural progenitor cell line C17.2

目的探讨外源性一氧化氮（NO）对小鼠神经祖细胞（NPC）增殖的抑制作用。

Objective To explore the inhibitive effect of exogenous nitric oxide ( NO ) on the proliferation of mouse neural progenitor cells ( NPCs ) .

YAP在鸡胚过度表达导致神经祖细胞池显著扩大。

In chick embryo , overexpression of YAP causes a marked expansion of the neural progenitor pool .

在运用再生类药物治疗ALS之前，了解体内成体神经祖细胞在运动神经元退行性病变过程中的组织与变化是极为重要的。

It is critical to understand the organization and distribution of endogenous adult NPCs in response to motor neuron degeneration before regenerative medicine can be applied for ALS therapy .

在ALS转基因小鼠模型中，体内神经祖细胞在疾病起始和进展阶段的重新组织与分布给刺激体内神经再生治疗ALS提供了坚实的理论基础。

The organization and distribution of endogenous adult NPCs in the ALS-like transgenic mice at the disease onset and progression stages provide fundamental bases for consideration of regenerative therapy of ALS by increasing de novo neurogenesis .

目的：了解丹参酮ⅡA对神经祖细胞系C17.2的保护作用，探讨其可能的作用机制。

AIM : To investigate the protective effect of Tanshinone ⅱ A on neural progenitor cell line C17.2 , and explore its possible mechanism .

目的探讨抗氧化剂在分离培养成年大鼠海马NG2蛋白聚糖阳性神经祖细胞（NG2细胞）中的重要作用。

Objective To explore the effect of antioxidants on the isolation and culture of adult rat hippocampal NG2 proteoglycan expressing progenitor cells ( NG2 cells ) .

体内移植iNPC及NPC发现细胞在异位组织不能增殖。结论：本研究成功建立永生化神经祖细胞系iNPC，实验证明其在体外无限增殖的可能性并不受限于培养条件。

In vivo transplantation iNPC and NPC found no proliferation cells in ectopic tissues . Conclusion : This study successfully established immortalized neural progenitor cell line iNPC , experiment proves the possibility of unlimited proliferation in vitro is not limited by culture conditions .

外源性一氧化氮对小鼠神经祖细胞增殖的抑制作用

Exogenous nitric oxide inhibits the proliferation of mouse neural progenitor cells

人类中脑神经祖细胞的体外扩增及诱导分化

The proliferation and differentiation of human mesencephalic progenitor cells in vitro

帕金森病模型大鼠黑质内神经祖细胞的增殖

The proliferation and differentiation of neural progenitors in the SN of parkinsonian rats

本研究结果提示，在胚胎发育晚期的脊髓套层内存在着具有增殖活性的神经祖细胞，它们可能是脊髓神经细胞产生的另外的来源。

These neural progenitors might be another source of the spinal neuron production .

长链多不饱和脂肪酸对成年大鼠海马由来神经祖细胞的影响

Effect of long-chain polyunsaturated fatty acids on the Hippocampal Progenitor Cells of adult rat

证明永生化神经祖细胞能够代表不同脑区，并具有多向分化潜能。

Proved immortalized neural progenitor cells could represent different brain regions , and multipotent of differentiation .

抗氧化剂在分离培养成年大鼠海马神经祖细胞中的作用

The effect of antioxidants on the isolation and culture of adult rat hippocampal neural progenitor cells

在侧脑室区，疾病进展期神经祖细胞的数目显著减少；而在海马区，无论在疾病的起始或进展阶段，都没有检测到神经祖细胞的变化。

Furthermore , a decrease of NPCs in the lateral ventricle at the disease progression stage was observed , while no difference in the number of NPCs in the hippocampus was detected at the disease onset and progression stages .

SVZ中的神经细胞祖细胞能形成切线形式的嘴侧迁移流（RMS）到嗅球，在嗅球分化成成熟的中间神经元。

The neuronal progenitors in the SVZ migrate tangentially along the rostral migratory stream into the olfactory bulb where they differentiate into local interneurons .

命运决定子Numb在神经干/祖细胞不对称分裂及分化中的调控作用

Regulatory Mechanism of Numb in Asymmetric Cell Division and Differentiation of Neural Stem / Progenitor Cells

人类神经干/祖细胞的体外扩增

The proliferation of human neural stem cells in vitro

原儿茶酸对体外培养的神经干/祖细胞增殖及凋亡的影响

Studies on the effects of protocatechuic acid on cell proliferation and apoptosis in cultured neural stem / progenitor cells

最近的研究表明，甘丙肽及其受体可表达于正常哺乳动物的胚胎干细胞和成年动物脑内增殖区域的神经干／祖细胞内，推测甘丙肽可能在神经发育过程中发挥一定的作用。

Recent reports have described that galanin and its receptors are expressed in embryonic stem cells of mammalian and in neural stem / progenitor cells located in the proliferation zones of SVZ in the brain of adult rat , which indicates that galanin may be involved in the neurodevelopment .

胶质细胞的神经干细胞/祖细胞特性

The Characteristics of Glia as Neural Stem Cells / Progenitors

血管内皮生长因子激活钙调神经磷酸酶促进内皮祖细胞增殖

Vascular Endothelial Growth Factor Promotes the Proliferative Capacity of Endothelial Progenitor Cells by Increasing Calcineurin Enzymatic Activity

迄今，关于脑缺血后神经干细胞或祖细胞的增殖、新生神经元向损伤部位迁移的分子机制所知甚少。

The molecular events underlying the proliferation of progenitors and the migration of newborn neurons into injured tissue after cerebral ischemia insults are only partly understood .

早期悬浮培养细胞以神经干细胞和祖细胞为主；而贴壁培养细胞则以谱系限制性神经前体细胞为主（80%）。

Cell population with suspension culture are basically composed of neural stem cells and progenitor cells in early stage , while adherent culture are chiefly formed by the NRP / GRP ( 80 % ) .

成年哺乳动物脑室下区（SVZ）富有神经干细胞、神经细胞祖细胞和胶质细胞祖细胞，它们能生成新的神经细胞、星状胶质细胞和少突胶质细胞。

The subventricular zone ( SVZ ) of the adult mammalian forebrain contains stem cells , neuronal progenitors and glial progenitors which give rise to neurons , astrocytes and oligodendrocytes .

在神经发育中，SHH调节神经管[2]的图式发育及神经祖细胞的增值和分化。

In the developing nervous system , SHH modulates patterning of the neural tube and regulates the differentiation and proliferation of neural stem cell .