细胞分化

DNA碱基序列重组作为决定细胞分化一个环节的逻辑可能性

The Logical Passability of The Somatic Recombination of DNA Nucleoside Sequences As One Link in the Cell Differentiation

结果显示，宫颈癌组DNA指数平均值明显高于正常组，且与肿瘤细胞分化有关；

The results showed that the DI in cervical cancer was higher than in normal group and was related with tumor cell differentiation .

DMSO诱导下蛋白激酶C与HL-60细胞分化的关系

Correlation between Protein Kinase C and Differentiation of HL-60 Cells Induced by DMSO

苦参碱诱导K562白血病细胞分化和凋亡的实验研究

Differentiation and apoptosis in K562 erythroleukemia cells induced by matrine

Notch信号与神经干细胞分化

Notch signal and neural stem cell differentiation

离心洗脱法在Rb蛋白与细胞分化关系研究中的应用

Application of Centrifugal Elutriation for the Study of Relationship between Rb Protien and Cell Differentiation

维甲酸诱导HL-60细胞分化与细胞周期的关系

Alteration of the Cell Cycle during the Differentiation of HL-60 Cells by Induction of Retinoic Acid

破骨细胞分化因子和护骨素mRNA在OVX小鼠骨组织的相对表达

The relative expression of receptor activator of nuclear factor-kappa B ligand and osteoprotegerin mRNA in bone tissue in ovariectomized mice

RANKL诱导类风湿性关节炎滑膜CD68阳性细胞分化为破骨细胞的实验研究

RANKL Induces CD68-positive Synoviocytes of Rheumatoid Arthritis into Osteoclasts in Vitro

目的研究镰刀菌毒素丁烯酸内酯（BUT）对软骨细胞分化的影响及硒（Se）的保护作用。

Objective To study the effect of butenolide ( BUT ) on cultured chondrocytes differentiation and the possible protective effects of selenium ( Se ) .

方法形态学观察和硝基四氮唑蓝还原反应鉴定DADS诱导HL-60细胞分化；

Methods Cell differentiation was validated by morphological method and nitroblue tetrazolium ( NBT ) reduction test .

目的：探索c-Myc、Fas和P53与成骨性肿瘤细胞分化的关系。

Objective : [ WT5BZ ] To investigate the relation between osteogenic tumour differentiation and expression of c-Myc , Fas and P 53 protein .

结论：NGF诱导PC12细胞分化的神经细胞能以无丝分裂方式增殖；

Conclusion : The neurons differentiated by NGF in cultured PC12 cells can divide in amitotic way .

目的：丹参提取物可诱导肿瘤细胞分化和凋亡，观察复方丹参药物血清对人BEL-7402细胞增殖的影响。

AIM Extract from dan-sen root can lead to the differentiation and apoptosis of tumor cells .

结果：PCNA在正常腮腺组织、腮腺多形性腺瘤及腮腺腺样囊性癌中呈阳性表达，但PCNA表达阳性率及强度与腮腺细胞分化程度相关；

Results : All cases showed PCNA positive expression but positive intensity and the positive rate correlated with the cell differentiation of parotid glan .

目的研究灵芝酯溶性提取物对PC12细胞分化的影响。

Aim To investigate the effects of lipophilic fraction of Ganoderma lucidum on PC12 differentiation .

IL-3对小鼠骨髓来源树突状细胞分化发育的影响

The Influence of IL-3 on the Differentiation and Development of Dendritic Cells from Mouse Bone Marrow

目的：构建能够报告人破骨细胞分化因子（ODF）基因启动子活性的表达载体。

Objective : To construct a specific reporter vector to monitor the activity of human osteoclast differentiation factor ( ODF ) gene promoter .

结论：ATRA可诱导A549细胞分化及凋亡，为临床应用ATRA化学预防肺癌提供理论依据。

Conclusion : ATRA could both induce differentiation and apoptosis of A549 cells . This observation may provide evidence for ATRA in chemoprevention of lung cancer .

目的：探讨细胞分化抗原CD117在各型白血病中的表达情况及意义。

Objective : To explore the expression of CD117 on different types of leukemia cells and it 's significance .

电离辐射对O-2A祖细胞分化影响的离体实验

Differentiation of O-2A Progenitor Cells after Irradiation in Vitro

目前异体来源的ESCs在临床应用上还需要攻克细胞分化机制、免疫排斥等问题，而治疗性克隆获得的ESCs虽可以解决免疫排斥问题，但其技术复杂、离分化完全的功能细胞距离较远。

Up to now , problems of the cell differentiation mechanism and immunological rejection of xenogenic resource ESCs meeted during clinical application were still not resolved .

对这些转录因子的调节以及各种其他因子的作用方式及对脂肪细胞分化机制的研究，可预防与治疗人类肥胖症、II型糖尿病等疾病，以及为减肥功能食品的开发提供理论依据。

Studies on the regulation of these transcriptional factors and mechanisms of adipocyte differentiation provides a theoretic basis for precaution or therapy of obesity , diabetes II and filtration of medicament for above disease , as well as for research of the functional food .

[结论]一定剂量的NGF能促进大鼠脊髓神经细胞分化和增殖，增强其活性。

[ Conclusion ] Certain concentration of NGF ( 20.0 ~ 80.0 ng / ml ) can promote the differentiation and proliferation of embryonic spinal cord neurons , and enhance the activity of the neurons .

目的：观察苦参碱诱导人肝癌细胞分化、凋亡时，G1细胞周期调节因子的变化，探讨苦参碱对肿瘤细胞增殖的调控。

Objective : To observe changes of cell cycle G1 phase regulation factors during matrine induced differentiation and apoptosis in hepatoma cells , and to investigate the function of matrine in regulating proliferation of tumor cell .

同时TGFβ能促进成纤维细胞分化，增加胶原生成，抑制胶原酶活性而降低胶原的分解，促进基质沉淀，引起移植器官纤维化及动脉粥样硬化，TGFβ的基因多态性与此密切相关。

Meanwhile TGF β also caused fibroblast migration and promoted matrix deposition by increasing collagen production and decreasing collagen breakdown via inhibition of collagenases , which resulted in transplant organ fibrosis and arteriosclerosis , gene polymorphisms of the TGF β were associated with it .

方法用苯丁酸钠诱导胶质瘤细胞分化，cDNA阵列检测诱导前和诱导2h、6d后的18000个基因表达，扫描仪分析结果，多点杂交验证。

Method The expression level of 18 000 genes in glioma cells was evaluated before and after induction with sodium phenyl-butyrate for 2 hours or 6 days by cDNA array technique , with the results proved by multi-dot blot .

神经干细胞分化后呈MAP-2、GFAP和CNP阳性的三种类型细胞，但分化的神经元数量较少、胞体较小、突起较少。

The differentiated cells expressed MAP-2 , GFAP and CNP , respectively , but the number of MAP-2 positive neurons was less , the size of cell body was smaller and the processes were scarce .

皮层和海马神经干细胞分化产生的Tuj-1阳性细胞分别是40.7%和19.3%；

Tuj-1 positive cells were 40.7 % and 19.3 % in the differentiated neural stem cells of cortex and hippocampus .

同时，还初步观察了PI3K信号通路对成骨细胞分化的调控作用。（4）BMP-2对成骨细胞分化的诱导作用并不直接通过活化MAPK信号通路来实现。

Meanwhile , the regulatory mechanism of PI3K on osteoblast differentiation was studied preliminarily . BMP-2 , the most potent regulator of osteoblast differentiation , did not directly depend on the activation of MAPK pathway to induce the differentiation of osteoblast differentiation .