代谢组
- 名metabolome
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槲皮素对氧化应激大鼠肝细胞代谢组的影响
The protective effects of quercetin on hepatocytes metabolome against oxidative stress in rat
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急性低氧暴露小鼠外周血代谢组变化分析
Effects of acute hypoxia on plasma metabolome in mice
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Sprague-Dawley大鼠肾脏急性缺血再灌注损伤的代谢组学研究
Metabolomics analysis of renal acute ischemia / reperfusion injury in Sprague-Dawley rats
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目的从粪便上清液代谢组学及基因组学探讨类风湿关节炎(Rheumatoidarthritis,简称RA)脾虚证的中医证候实质。
Objective : To study the spleen deficiency syndrome of rheumatoid arthritis from fecal supernatant metabonomics and Genomics of traditional Chinese medicine .
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LC/MS/MS结合主成分分析(PCA)用于鼠尿中灯盏花素代谢组学的研究
Application of the Liquid Chromatography Coupled to Tandem Mass Spectrometry with Principal Components Analysis for Metabonomics Studies of Scutellarin in Rat Urine
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经前期综合征(PMS)肝气逆证代谢组学研究
Metabonomics Study on Premenstrual Syndrome with Liver-qi Invasion
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目的:采用核磁共振(NMR)代谢组学法研究雷公藤多苷片对大鼠代谢的影响。
Objective : To investigate the toxic effects of Glucoside Tripterygium total on rats with nuclear magnetic resonance ( NMR ) - based metabonomic method .
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代谢组学数据中的噪音属性很可能会对SVM最优超平面的构建产生影响,进而影响到对特征的评价。
Noise features in metabolomics data are likely to impact the construction of the optimal hyper-plane in SVM . thus can affect the evaluation of features .
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CCL4诱导大鼠肝损伤模型的代谢组学及茵陈蒿汤的干预作用研究
Metabonomics of CCL4-Induced Rat Liver Injury and Interfering Effects of the Yin Chen Hao Tang Extract
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利用代谢组学技术对功能性消化不良(FD)女性患者血浆中代谢产物的变化进行研究。
Metabonomics was applied to study the changes in plasma metabolites of female patients with functional dyspepsia ( FD ) .
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以上结果表明,代谢组学技术能够对FD女性患者血浆中代谢产物的变化进行客观评价。
These results suggested that , changes in plasma metabolites of female patients with FD could be evaluated by metabonomics objectively .
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目的:建立测定K562及K562/A细胞内核苷类代谢物含量的高效液相色谱法,用于两者代谢组学研究。
Objective : To establish a reversed-phase ion-pair high-performance liquid chromatographic method for simultaneous determination of nucleotides and nucleosides in K562 and K562 / A cell lines .
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本文简要介绍了核磁共振波谱技术的基本原理、多维NMR以及在结构鉴定、构象分析、医学临床检测、蛋白质组学、代谢组学等方面的应用。
This article mainly introduces the principle of NMR , multidimensional NMR and their application in structural identification , conformational analysis , clinical check of iatrology , proteomics , metabolomics , and so on .
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基于NMR代谢组学研究显示与正常组相比,痛风组1H-NMR图谱中丁酸、丙酸、乙醇、谷氨酰胺、牛磺酸、葡萄糖等代谢物的谱峰有了明显的改变。
In the metabolomics studies , compared with normal group , butyric acid , propionic acid , ethanol , glutamine , taurine , glucose in the gout group have obviously changed .
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气相色谱-质谱联用(GC-MS)是代谢组学研究中常用的分析技术之一,具有分辨率和灵敏度高,取样量少等的特点,并且有可用于快速鉴定代谢物的商业化质谱数据库。
Gas chromatography-mass spectrometry ( GC-MS ) technique is one of the commonly used analysis technics in metabonomics , which is characterized by high resolution and sensitivity , with a commercialized MS database for rapid identification of metabolites .
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本研究运用病证结合手段,采用液相色谱-质谱联用(LC-MS)技术的代谢组学方法,以代谢综合征为基础病探讨其脾气虚患者尿液中小分子代谢组成分。
We investigated the small molecular metabolite in urine of Metabolism syndrome patients as the foundation of spleen qi deficiency using method of disease and syndrome with combination and liquid chromatography-mass spectrometry technology .
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基于NMR的代谢组学分析方法为探讨GDM的病理机制提供一个很好的技术平台,并将在GDM的早期诊断和个体化治疗等方面的研究具有广阔的应用前景。
Results have shown that the NMR-based metabonomics approach provides a robust technical platform to study the pathomechanism on GDM , and will have broad application prospects in early diagnosis and individual therapy of GDM in the future .
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表明利用代谢组学研究尿液中的代谢物,可以为HLP的诊断和发病机制提供一个可借鉴的手段;
It was noted that the research of metabolites in the urine samples may be a useful tool to help diagnose and understand the pathogenesis of HLP .
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论文主要是将RJMCMC算法应用于代谢组学的核磁共振信号处理中。
In this paper , a Reversible Jump Markov chain Monte Carlo ( RJMCMC ) algorithm is applied to signal processing of NMR-based metabonomics .
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代谢组学(Metabonomics)能够反映细胞、体液的内源性和外源性代谢物浓度与机体功能之间的关系,已在医学、生物学等众多领域得到广泛的应用。
Metabonomics can reflect the relationships between the organism function and concentration of endogenous and exogenous metabolites which in the cells and body fluids , and has been widely used in the research of pharmacology and biological sciences .
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而气相色谱-质谱(GC-MS)联用技术具有较强的分离分析能力,灵敏度高,操作简便,而且有商品化的标准质谱数据库,可对代谢物的结构进行快速鉴定,适合于代谢组学分析。
Gas chromatography-mass spectrometry ( GC-MS ) is a better and mature technique with searchable standard database , excellent separating , qualitative abilities with a high sensitivity and easy operation , which facilitates the identification of metabolites . Thus GC-MS considered as an ideal tool is suitable for metabonomics analysis .
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探讨了灌胃槲皮素对大鼠尿液代谢组的影响。
The effects of quercetin on urine metabolic profiles were investigated .
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中医证候标准化现代化研究与代谢组学方法的应用
Standardization study on syndrome of TCM and the application of metabonomics
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龙胆对大鼠尿液影响的代谢组学初步研究
Metabonomics preliminary study on the urine of radix gentianae administrated rats
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高血压病阴虚阳亢证的代谢组学研究
Study of Hypertension Yin Deficiency and Yang Excess Syndrome on Metabonomics
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代谢组学评价黄连对大鼠药理作用的初步研究
Study of metabonomics on pharmacological action appraisal Rhizoma Coptidis in rats
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骨髓增生异常综合征中医证型的代谢组学分析
Metabonomics Analysis of Traditional Chinese Medicine Patterns in Patients with Myelodysplastic Syndrome
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基于代谢组学技术的辛伐他汀对磷脂类物质作用的初探
Study the effects of simvastatin on phospholipids by metabonomics-based technique
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核磁共振代谢组学数据处理新方法及应用
New Methods of NMR-based Metabonomics Data Processing and Its Application
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应用代谢组学方法对细菌培养体中霉菌毒素的研究
Research of Mycotoxin in Bacteria Culture Medium by Application of Metabolomic Method