代谢通路

Keasling博士并不是唯一一个想产生人工代谢通路的人。

Dr Keasling 's project is not the only one to lay down artificial metabolic pathways .

其他未发现的与口吃相关的基因是否也与代谢通路有关？

Do other undiscovered genes associated with stuttering have roles in metabolic pathways ?

细胞中有许多生物反应通路，比如物质代谢通路、基因表达通路、DNA复制通路、信号转导通路等等，其中最复杂的就是信号转导通路。

There are many biological response paths in a cell , such as material metabolism paths , gene express paths , DNA duplication paths , signal transduction paths and so on .

本实验室通过合理改造Pichiapastoris的代谢通路，获得了一株组成型表达SAM合成酶2（SAM2）的重组P.pastoris菌株。

By changing Pichia pastoris metabolic path rationally , a constitutive recombinant Pichia pastoris with riched SAM synthetase was obtained .

糖尿病是一种伴有诸多严重并发症的疾病，在退行性糖尿病并发症病变的发生和发展过程中，多元醇代谢通路（Polyolpathway）起了十分重要的作用。

Diabetes mellitus ( DM ) is a serious disease with severe complications . Polyol pathway plays an important role during the development of degenerative diabetic complications .

该酶被认为催化了固醇生物合成、环丙烷和环丙稀脂肪酸生物合成、环丙烷脂肪酸（CFA）生物合成等三个代谢通路中的四个反应。

This protein was thought to be able to catalyze 4 reactions in 3 different pathways , sterol biosynthesis , cyclopropane and cyclopropene fatty acid biosynthesis , cyclopropane fatty acid ( CFA ) biosynthesis .

KEGG通路分析表明，在感染48及72h后，大多数涉及到代谢通路的基因的表达水平发生了下调，所有涉及到核糖体通路和蛋白酶体通路的基因的表达水平均发生了上调。

KEGG pathways analysis indicated that at 48h and 72h post-inoculation , most genes related to metabolism pathways were down-regulated while expressions of genes involved in ribosome and proteasome pathway were all up-regulated .

甲基黄酮醇胺对血小板花生四烯酸代谢通路的影响

Effects of methylflavonolamine on arachidonic acid metabolism pathway of platelet

因此，通过对各种糖代谢通路进行有针对性的干预，有望开发出新型治疗药物。

Hence it is hopeful to exploit new therapeutic drugs by pharmacological interference glycometabolism pathway .

介绍褪黑素的合成、代谢通路及其抗氧化、抗细胞凋亡等神经保护作用。

The pathway of synthesis and metabolism , and neuron-protective effect of melatonin were introduced .

背景和目的：铁在人脑中存在小脑-脑干-基底节这一代谢通路。

Background and Purpose : Iron in brain has a metabolic pathway of " cerebellum-brain stem-basal ganglia " .

复方丹参片对糖尿病大鼠坐骨神经功能和多元醇代谢通路的影响

Effects of Tablet Compound Red-rooted Salvia on Function of Sciatic Nerve and Polyol Metabolic Pathway in Diabetic Rats

代谢通路分析的研究中主要有两种方法，基元模式和极端途径。

There are two methods in the research of the metabolic pathways : elementary flux modes and the extreme pathways .

根据虎皮楠生物碱与角鲨烯代谢通路间的关系，初步探索了这类生物碱的生物功能。

Furthermore , biological functions of Daphniphyllum alkaloids were initially seeked after based on their relation to squalene metabolism pathway .

在不久的将来这种技术就可以把来自不同物种的基因组装在一起产生新的代谢通路，甚至产生新的物种。

In the short run such engineering means assembling genes from different organisms to create new metabolic pathways or even new organisms .

然而，当铁的代谢通路受到脑内损伤的影响时，会在脑内深部核团发生铁沉积现象。

However , iron deposition in the deep brain nucleus will take place , when the iron metabolic pathway is affected by cerebral lesion .

以便进一步探讨产生异戊二烯的甲羟戊酸和类异戊二烯代谢通路及其代谢异常在精神分裂症病理生理机制中的作用。

The aim of this study was to explore the role of the mevalonate pathway and the isoprenoid pathway in the pathogenesis of schizophrenia .

这些蛋白被认为参与了一些重要的细胞信号转导和代谢通路，并且这些信号转导和代谢通路与细胞的表面识别和细胞外被的降解有关。

These proteins were thought to be associated with several important cell signaling or metabolic pathways during the cell surface recognition and extracellular glycocalyx destruction .

此外，一些细胞内的代谢通路似乎在不同的人类谱系当中有所不同，如谷氨酸，氨基丁酸和钙/钙调信号途径。

Furthermore , intracellular responses to several cellular pathways seem to be different in the human lineage , such as glutamate-GABA-and calcium / calmodulin-signaling pathways .

与NO产生相关的内皮中3-磷酸激酶依赖的胰岛素信号通路，与骨骼肌中促进葡萄糖摄取的代谢通路有着惊人的相似。

PI 3-kinase-dependent insulin signaling pathways in endothelium related to production of NO share striking similarities with metabolic pathways in skeletal muscle that promote glucose uptake .

当然仅仅一条人工代谢通路不能最终能够证明合成生物学的成功，需要的是人工生物来证明。

The ultimate proof of the success of synthetic biology , though , would be not merely an artificial metabolic pathway , but an artificial organism .

最后，为了方便使用，采用动态布局的可视化用户界面，设计实现了一个代谢通路可视化集成工具。

In addition , considering a friend interface for end user , a metabolic pathway visualized integration tool was designed and implemented using dynamic layout graphic user interface .

生物体内不同构型的氨基酸在传递神经信息、调节代谢通路及肽和蛋白质的合成等许多生理过程中起着不同的作用。

And their functions in the course of the transferring of nerve information , adjusting of metabolize pathway , and the sythesis of peptides and proteins are vary .

醛糖还原酶是多元醇代谢通路中的限速酶，醛糖还原酶抑制剂能有效抑制此通路，减慢或改善糖尿病并发症。

Aldose reductase is a key rate ? limiting enzyme in the pathway , while aldose reductase inhibitors can inhibit the pathway and alleviate the symptoms of diabetic complications .

背景：瘦素是一种主要由脂肪组织分泌的激素，影响机体许多生理系统和代谢通路，并与许多疾病关系密切。

BACKGROUND : Leptin , one of hormones secreted from adipose tissues , has an effect on many physiological systems and metabolic pathways and is closely related to many diseases .

我们还发现，尽管清除速率存在种属差异，但不管在大鼠肝微粒体还是在人肝微粒体中Ⅱ相通路都是贝特类药物的主要代谢通路。

It was also found that the phase II pathway in either rat liver microsomes or human liver microsomes are the major pathway for fibrates despite the species difference in term of elimination velocity .

本课题通过生物信息学手段从酿酒酵母细胞核代谢通路中查找了到近百种核内小分子，它们大多是一些氨基酸、核苷酸或其结构类似物。

In this subject , nearly 100 hundred nuclear chemicals had been selected from the pathway in nuclear of Saccharomyces cerevisiae by the method of bioinformatics . Most of the nuclear chemicals were amino acid , nucleotide and their analogues .

很多代谢通路出现了差异表达，涉及到蔗糖降解、丙酮酸盐合成、乙醛酸循环、三羧酸循环、戊糖磷酸途径、莽草酸途径、脂肪酸β氧化、氨基酸合成。

Many metabolic pathways were involved in differential expression , which include sucrose degradation , synthesis of pyruvate , glyoxylae cycle , TCA cycle , pentose-phosphate pathway , shikimic acid pathway , fatty acid oxidation , and synthesis of amino acid .

利用近期公布的大豆全基因组序列信息可研究大豆目标基因（家族）在代谢通路中的作用，揭示其分子进化特点，其与分子遗传学研究相结合则可更全面掌握目标基因的遗传规律。

The released whole-genome sequence of soybean can be utilized to reveal the function and molecular evolution of the target gene ( protein family ), and the overall understanding of the gene characters can be obtained through combining the methodologies of molecular biology with evolutionary analysis .

研究发现，成人高GC暴露与外周组织胰岛素抵抗相关的代谢信号通路之间存在着网络调控。

Other investigations show that there are cross-linked regulations between high GC exposure to adult and peripheral insulin resistance related signal pathways .