内吞
- 网络endocytosis;internalization;RME
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受体介导内吞对巨噬细胞膜电位、胞浆和溶酶体pH的影响
Effects of receptor-mediated endocytosis on macrophage mebrane potential , cytosolic pH and lysosomal pH
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神经节苷脂GM1和GM3对受体介导的转铁蛋白内吞过程的影响
The effect of ganglioside gm_1 and gm_3 on receptor-mediated endocytosis of transferrin
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结论同一种外源性抗原被DC和巨噬细胞内吞后,在这两类细胞中的运行路径明显不同。
Conclusion The endocytic route of exogenous antigen in DC apparently differs from that in macrophages .
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用流式细胞仪测内吞FITC标记的dextran的DC的百分率。
Detect the phagocytosis FITC labeled dextran capacity of DC flow cytometer .
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肺腺癌细胞对谷胱甘肽纳米Fe3O4的内吞作用
Endocytosis of lung adenocarcinoma cell on glutathione modified magnetite ( Fe_3O_4 ) nanoparticles
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PE结构域Ⅱ的作用是使裂解后的毒素部分或其他效应分子从内吞体转位到细胞质。
The function of domain II is to translocate the cleaved part of the toxin or other effectors from endosome to cytosol .
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而红细胞对外源SOD的少量吸收主要是通过内吞胞饮作用实现的,整个过程可能是由红细胞膜上的SOD载体介导的。
RBCs absorb outer SODs by pinocytosis . The process may be initiated by the binding of SODs and SOD receptors .
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三种细胞被广泛应用于细胞毒性检测,内吞作用,新陈代谢,繁殖以及RNA表达等课题的研究,是比较具有代表性的细胞模型。
These cell lines are typical models widely used in studies of cytotoxicity , endocytosis , metabolism , proliferation and RNA expressions .
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结论内吞体功能复杂,它可能与细胞的pH值,水盐代谢,能量、蛋白质的代谢以及活性氧的产生等都有一定的关系。
Conclusion Endosome has complicated function and probably relates with cellular pH , the metabolism of water and salt , the metabolism of energy , protein and the production of active oxygen .
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结论1.外源性和内源性H2S可抑制巨噬细胞内吞ox-LDL。
Ectogenic and endogenic hydrogen sulfide can suppress the cellular uptake ability of ox-LDL by macrophages . 2 .
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小鼠腹腔巨噬细胞的conA受体分布及受体介导内吞
The distributing of conA receptor on macrophage membrane and the phagocytic activity mediated by the receptor
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在近年的研究中发现Numb作为细胞内吞蛋白在神经发育过程中发挥重要作用。
Numb as an endocytosis protein plays an important role in the nerve development process in recent studies .
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细胞通过低密度脂蛋白受体(LDL-R)介导的LDL内吞及自身合成而保持胞内胆固醇的平衡。
Cellular cholesterol balance is maintained by low density lipoprotein ( LDL ) mediating the uptake of exogenous cholesterol and the synthesis of cholesterol within cell .
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通过这种方法,蒋澄宇的课题组鉴定出非典病毒并不依赖内吞作用的常规途径进入细胞。而一处名叫脂质筏(lipidrafts)的结构则在非典病毒进入细胞中发挥了重要作用。
By doing so , the research team identified that the SARS virus does not rely on the conventional endocytic pathways to enter cells .
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丙酸睾酮对鸡的法氏囊表面上皮内吞作用(Endocytosis)的影响
Effects of testosterone propionate on endocytosis of the surface epithelium of bursa FABRICII in chicks
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分泌到细胞外基质中的DCN,可被纤维母细胞通过内吞作用内化后,经溶酶体降解。
DCN secreted into the extracellular matrix can be degraded through lysosomal after endocytosis by fibroblasts .
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用pH值敏感荧光探针Snaflcalcein-AM标记体外培养48小时的小鼠腹腔巨噬细胞,570型粘附式细胞仪观察巨噬细胞在对刀豆素A进行受体介导内吞过程中细胞内pH值的变化。
By using fluorescence staining method , the effect of receptor-mediated endocytosis on intracellular pH ( pHi ) of mouse macrophages was studied with adherent cell analysis and sorting cytometer 570 ( ACAS 570 ) .
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HCMV病毒感染细胞的过程是从病毒包膜糖蛋白与靶细胞膜表面受体结合开始的,结合后HCMV以膜融合或受体介导的内吞机制进入细胞。
HCMV infection starts from the viral envelope glycoprotein binding with the cell surface receptor . Then HCMV enters cells by membrane fusion or receptor-mediated endocytosis .
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本文采用电子显微镜对胶体金标记刀豆素A(ConA-Au)与小鼠腹腔巨噬细胞表面ConA受体的结合、内吞及其在巨噬细胞中转运的形态学变化;
The binding , internalization and intracellular routing of colloid gold labeled ConA ( ConA Au ) have been studied in mouse peritoneal macrophages by electron microscopy .
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尺寸合适的SWNT能够通过内吞进入细胞内,具有药物载体的潜质。
As the ability to enter cell by endocytosis , SWNT with suitable size is potential drug carriers .
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窖蛋白-1(caveolin-1)是胞膜窖的主要结构成分,在细胞内吞、胆固醇运输、信号传导、肿瘤转化中发挥着重要的作用。
Caveolin-1 is a major structural protein of caveolae and plays important roles in signal transduction , cellular transformation and tumor metastasis .
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电镜观察表明:ConA的内吞属于受体介导内吞,低温对其有抑制作用。
Electron microscopic studies indicated that endocytosis of ConA belonged to the receptor mediated endocytosis ( RME ), which could be inhibited by low temperature .
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方法通过透射电镜(TEM)与普鲁士兰染色法观察SPC-A1细胞对GSSG修饰的纳米Fe3O4的内吞作用。
Methods The uptake of GSSG-modified Fe_3O_4 nanoparticles by SPC-A1 cell was observed by transmission electron microscopy ( TEM ) and Prussian blue staining .
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内吞后30分钟,巨噬细胞摄入的大部分抗原进入溶酶体,而DC则将大部分抗原送入MIC,这可能与DC独特的抗原提呈功能有关。
Most of antigens taken by macrophages enter into lysosomes within 30 minutes . In the case of DC , most of internalized antigens enter into MIICs , which may be related to their unique antigen presenting function .
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晚期糖基化修饰白蛋白在实验性BREC内吞中的作用
The Function of AGE-modified Bovine Serum Albumin in Experimental Endocytosis of BREC
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q细胞的分泌活动是神经元释放神经递质、内分泌细胞分泌激素和细胞膜上功能蛋白的镶入和内吞等生命活动的基础,对于生物体正常机能的维持是必需的。
The activity of secretion is the basis for transmitters release from neurons , hormones secretion from endocrine cells and setting or endocytosis of functional membrane proteins , which are absolutely necessary in maintaining normal physiological function of organisms .
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RodriguezA在Nature报道吞噬可溶性抗原转运到胞浆,进入MHC-I类分子递呈途径,却一直未能鉴定外源抗原从内吞囊泡到胞浆的转运机制。
Rodriguez A reported that soluble antigens are transport to cytosol and enter the classic MHC I restricted pathway , while the mechanisms of exogenous antigen transport from phagosome to cytosol remains uncovered .
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方法:在不同温度及细胞松弛素B处理前后对人肺腺癌细胞SPC-A1进行培养,通过透射电镜动态观察细胞对氨基硅烷纳米Fe3O4的不同内吞情况。
Methods : Human lung adenocarcinoma SPC-A1 cells were cultured at different temperatures or at 37 ℃ with or without cytochalasin B treatment . The dynamic endocytosis of aminosilane-coated Fe_3O_4 nanoparticles was observed by transmission electron microscopy .
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作为质膜上的独立结构,胞膜窖参与多种细胞活动,如胆固醇转运、细胞内吞(endocytosis)、细胞膜组装、信号转导、肿瘤生成等。
As distinct domains of the plasma membrane , caveolae participate in many cellular processes such as cholesterol trafficking , endocytosis , membrane sorting , signaling and oncogenesis .
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因此,它在DNA的修复、细胞周期运转、信号转导、转录水平上的调节、细胞内吞、抗原呈递、细胞凋亡等过程中具有非常重要的作用。
So the ubiquitin pathway plays an essential role in DNA repair , progression through the cell cycle , signal transduction , transcriptional regulation , the nuclear transport process , receptor control by endocytosis , the processing of antigens in the immune system , pathological alterations and programmed cell death .