噬菌体抗体
- 名phage antibody
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结论成功地构建出了一个有效库容量为4.75×106的鼠抗LPS单链噬菌体抗体库。
Conclusion A 4.75 × 106 murine anti-LPS single chain phage antibody library was successfully constructed .
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结论:所获得的表达载体pAL适用于构建大容量Fab噬菌体抗体库。
Conclusion : pAL is useful for construction of large phage antibody libraries .
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利用pⅧ展示系统改进噬菌体抗体芯片
Improving Phage Antibody Chip by p ⅷ Display System
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应用细胞内PCR技术构建及筛选白癜风噬菌体抗体库
Construction and screening of human vitiligo phage autoantibody library based on in-cell PCR
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目的构建B细胞淋巴瘤Fab噬菌体抗体库。
Objective To construct Fab phage display library against human B-lymphoma .
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结论用分子生物学手段制备并纯化了人工重组抗原B,为批量生产诊断抗原、制备单克隆抗体及筛选噬菌体抗体库奠定了基础。
Conclusion Hydatid disease antigen B can be produced by molecular method and applied in monoclonal antibody production and phage antibody library scanning .
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抗HBsAg人源噬菌体抗体重链基因的序列分析
DNA sequence analysis of heavy chain of human phage antibody to HBsAg
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轻链替换提高抗HBsAg噬菌体抗体的结合力
Improvment in affinity of phage antibodies against HBsAg by light chain shuffling
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目的评价菌落PCR法鉴定噬菌体抗体库阳性重组率的可靠性。
Objective To evaluate the reliability of colony PCR in identifying the recombinant clones selected from phage antibody libraries .
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抗HCV解旋酶人源性单链噬菌体抗体的筛选
Screening of Human ScFv Antibody of HCV Helicase
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人抗HBsAg噬菌体抗体Fab段基因的序列分析及表达
Sequence analysis and expression of anti HBsAg phage antibody Fab gene
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从人源性噬菌体抗体库分离出1株含有异常序列的抗HBsAgFab克隆
A human anti-HBsAg Fab with abnormal sequences cloned from phage antibody library
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目的构建人免疫缺陷病毒1型(HIV-1)特异性噬菌体抗体库,制备人源抗HIV-1gp120单克隆抗体。
Human monoclonal antibodies to type 1 immunodeficiency virus ( HIV-1 ) gp120 were generated from phage antibody combinatorial library .
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SLE患者自身抗体单链噬菌体抗体库构建及抗体活性检测
Patients with SLE and Detection of Antibody Activities
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从噬菌体抗体库克隆抗人RBC单链抗体基因
ScFv against human RBC from phage antibody library
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在本研究中,我们采用噬菌体抗体库技术,成功地从1例长期带瘤生存的MM患者体内克隆到特异性抗MM细胞的抗体,为进一步的研究和应用奠定了基础。
The successful preparation of specific antibodies against MM cells by phage display technology paves the way for further study and application .
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斑点叉尾鮰天然Fab噬菌体抗体库的构建
Construction of Channel Catfish Naive Fab Fragment Phage Display Antibody Libraries
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抗华支睾吸虫CAg噬菌体抗体表达与活性鉴定
Expression and identification of phage antibodies against clonorchis sinensis CAg
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噬菌体抗体库(phageantibodylibrary)是将人抗体基因与噬菌粒载体相连,在细菌体内表达而制备的人全套抗体(repertoireofantibodies)。
Phage antibody library is a repertoire of antibodies , which connects human antibody genes to phagemid vector and is expressed in bacteria .
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新式SOEPCR高效组装人单链抗体在高容量人天然噬菌体抗体库中的应用
Application of an improved efficient SOE PCR in assembling scFv genes during construction of large human antibody library
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用噬菌体抗体库分离NK细胞抑制受体特异性的ScFv片段
Isolation of ScFv fragment specific for human NK cell inhibitory receptor from the phage
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人源化抗血小板膜糖蛋白GPⅡb/Ⅲa单链噬菌体抗体的研究
Study on Humanized Anti-Platelet GP ⅱ B / ⅲ A Phage Single Chain FV Antibody
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目的:用黑素瘤(MM)细胞系筛选大容量人源噬菌体抗体库,获得能与MM细胞特异性结合的人源性单链抗体(scFv)。
AIM : To obtain the specific human scFv against malignant melanoma ( MM ) using phage antibody library technology .
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抗恶性疟SERA噬菌体抗体库的构建及单链抗体的筛选与鉴定(英文)
Construction of anti-SERA phage-displayed antibody library and the screen and identification of single chain Fv antibodies ( ScFvs )
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目的构建针对B细胞淋巴瘤Raji细胞系噬菌体抗体库并从中筛选出特异性的抗体。
AIM : To construct and screen the specific Fab phage antibody library against human Raji cell strain in B-lymphoma .
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人源抗HAV噬菌体抗体的筛选及基因序列分析
Selection of human phage antibodies against HAV and DNA sequence analysis
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目的用噬菌体抗体库技术克隆抗人红细胞(RBC)的单链抗体(ScFv)基因。
This work intended to clone anti human RBC ScFv gene from phage antibody library .
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人-鼠杂合Fab噬菌体抗体库的建立大容量人源噬菌体抗体库的构建
Construction of human-mouse hybrid Fab phage antibody libraries Establishment of large phage antibody library
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SARS-CoV免疫噬菌体抗体库的构建及筛选
Construction and Panning of Immune Phage Antibody Library Against SARS-CoV
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方法:应用错配PCR技术在抗TNFαscFv基因中引入随机突变,再通过DNA交换(shuffling)使引入的点突变进一步重排组合,构建突变噬菌体抗体库。
METHODS : A mutant phage antibody library derived from an anti-TNF - α scFv gene was generated by error-prone PCR .