基因疗法

现在对基因疗法下结论还为时过早。

It is far too early to make sweeping statements about gene therapy .

作为律师，我会反对在现阶段对基因疗法进行任何形式的法律管制。

As a lawyer , I would deprecate any sort of legal control on gene therapy at this stage .

基因疗法使用DNA治疗疾病，而不是使用蛋白质或药物。

Gene therapy involves the use of DNA , rather than a protein or drug , to treat an ailment .

成纤维细胞介导的人IL-10基因疗法的实验研究

Study of experimental model of interleukin 10 gene therapy with fibroblasts

脂质体介导的腹腔内IL-2和IL-6基因疗法对淋巴瘤小鼠巨噬细胞的激活作用

Activation of macrophages from lymphoma bearing mice by liposome mediated intraperitoneal IL 2 and IL 6 gene therapy

成纤维细胞介导的G-CSF基因疗法促进化疗后造血功能恢复的实验研究

The Enhancing Effects of Fibroblast-Mediated G-CSF Gene Therapy on the Recovery of Hematopoiesis

葡萄糖糖酵解酶、热休克蛋白（HSP）、磷酶甘油还原酶B（PGMB）及基因疗法可提高机体对缺氧的耐受性和适应性。

Glucose glycolysis enzyme , HSP , PGM B and gene treatment may increase the tolerance and adaptability of mitochondria to anoxia .

因此，较其它基因疗法如RNAi、DNAdecoy等，更能有效地抑制HIV复制，并且对由HIV变异而导致的耐药病毒株同样有效，同时对病毒突变的诱导作用也较其它抗病毒药物低。

Compared with other gene therapies such as RNAi and DNA decoy , ribozymes could inhibit the replication of HIV more effectively including HIV persisters ;

IOC的官员担心，基因疗法使得运动员能够将HGH基因注入自身的DNA而躲过检测。

IOC officials fear that gene therapy could allow athletes to insert the HGH gene in their DNA and avoid detection .

【结论】含CEA启动子的CD基因疗法可能是胰腺癌靶向性基因治疗的可行途径。

Conclusion These results demonstrate that utilization of the CEA promoter in an adenoviral vector may be a potential approach for targeting gene therapy of pancreatic carcinoma .

这与当前仍处临床试验阶段的“基因疗法”有本质的不同。基因疗法治疗遗传病时，会把DNA加入到患者受损的细胞中，但这种变化不会遗传给后代。

This is fundamentally different to " gene therapy , " currently in clinical trials , which treats genetic diseases by adding DNA to patients " affected cells but does not transmit changes to their offspring .

HSV-tkGCV自杀基因疗法及其影响树突状细胞功能的实验研究

Experimental studies on the characteristics of suicide gene system HSV-tk / GCV and its effect on dendritic cells

BMP的人工骨和局部基因疗法研究为修复骨缺损提供了新途经。

The research on bone morphogenic protein and its combined human bone and local gene therapy afford new ways for bone defect repairing .

阳离子脂质体介导的HSV-tk自杀基因疗法的体内外抗肝癌作用

The Effect of Anti-Hepatocellular Carcinoma of HSV-tk Gene Therapy Mediated by Cationic Liposome in vitro and in vivo

Egr-1启动子调控的造血因子基因疗法对SCID小鼠辐射防护的初步探讨

Radioprotective effect of hematopoietic growth factor gene therapy regulated by Egr-1 promoter on radiation injury of SCID mice

研究了成纤维细胞介导的IL－3基因疗法、IL－6基因疗法以及两者联合后对造血系统的影响。

In the present study , investigated the effects of fibroblast-mediated interleukin-3 ( IL-3 ) gene therapy , interleukin-6 ( IL-6 ) gene therapy or their combination on the hematopoietic regulation .

腺病毒载体介导的IL-3基因疗法对放射损伤小鼠造血功能重建的影响

Interleukin-3 gene therapy mediated by recombinant adenovirus vector on hemopoietic reconstitution of mice injured by 5 Gy γ irradiation

综述骨形态发生蛋白（BoneMorphogenicProtein，BMP）的成骨机理及其复合人工骨和局部基因疗法在治疗骨缺损中的研究进展。

We reviewed the recent advances made in research on bone morphogenic protein regarding its mechanism of osteogenesis and on effect of combined human bone and local gene therapy in bone defect repairing .

间充质干细胞（MesenchymalStemcells，MSCs）基因疗法是近几年提出的修复肌损伤的新思路。

Thus , how to repair muscle injury has been considered a heat and difficult issue for a long time . In recent years , gene therapy with mesenchymal stem cells ( MSCs ) has been studied in the treatment of injury of muscle .

美国Beckman研究所的分子生物学教授JohnRossi领导的一个研究组正在试验基因疗法。在该疗法中，基因被注入到了细胞或组织中，用于治疗艾滋病。

A team headed by John Rossi , professor of molecular biology at the US-based Beckman Research Institute , is testing gene therapy , where genes are injected into cells or tissue to treat disease .

总之，miRNA干扰沉默SOD2基因疗法可以应用于放疗抵抗的鼻咽癌，能使癌症放疗的放射敏感性增高。

The results presented suggest that miRNA interference silencing SOD2 gene therapy may be applicable to the radioresistant nasopharyngeal carcinoma , enabling radiosensitivity escalation in cancer radiotherapy .

FDA说在其他基因疗法的实验中并未见到任何相似的问题，然而，为了预防起见，所有已在进行的应用AAV传递方法的实验都在调查之中。

The FDA said it was not aware of any similar problems in other gene therapy trials but , as a precaution , was reviewing all ongoing trials that used the AAV delivery method .

结论：人成纤维细胞株KMB17可以作为靶细胞用于BMP2基因疗法研究。

Conclusion : The human fibroblast strain KMB 17 can be used as target cells in BMP 2 gene therapy study .

一种将DNA直接植入眼睛以逆转某类儿童视力丧失的开创性疗法，有望得到美国监管机构的批准。此前，一个由科学家组成的顾问委员会对这种由SparkTherapeutics公司研发的“基因疗法”表示了一致的支持。

A pioneering treatment that can reverse a form of childhood vision loss by inserting DNA directly into the eye is on track for regulatory approval in the US , after a panel of scientists endorsed unanimously the " gene therapy " being developed by Spark Therapeutics .

XIAP蛋白的基因疗法能够保护濒临死亡的这一眼睛的重要组成部分的细胞，在保护视力造成重大。

XIAP gene therapy was able to protect the cells of this critical part of the eye from dying , resulting in significant preservation of vision .

目的：研究肿瘤的自杀基因疗法，建立含单纯疱疹病毒胸苷激酶（HSVtk）基因重组逆转录病毒包装细胞PA317/TK。

Objectives : In order to study suicide gene therapy on tumor , we constructed the package cell PA317 / TK with recombinant retroviral vector containing HSVtk gene .

尤其重点介绍了高强度聚焦超声（HIFU）无创外科、超声增强药物传递、超声基因疗法、超声血管成形术、肝癌的超声血管阻断疗法，并展望了超声治疗技术的发展前景。

Especially this paper mainly introduces HIFU unwound surgical department , ultrasound strengthen the transfer of medicine , ultrasound gene treatment , ultrasound angioplasty and blocking vascular treatment of liver cancer , and then prospects the development perspectives of ultrasound treatment technology .

药敏基因疗法（或自杀基因疗法）是基因治疗方法中的一种，以单纯疱疹病毒胸苷激酶基因（HSV-tk基因）做为目的基因在药敏基因疗法中应用最广。

Drag sensitivity gene therapy ( or suicide gene therapy ) is one of approach of gene therapy . In this approach , Herpes Simplex virus thymidine kinase ( HSV-tk ) gene is the most useful target gene .

T6.6体内移植后能显著增强淋巴细胞增殖反应和IL-2产生水平。表明成纤维细胞介导的IL-6基因疗法能有效地增强免疫功能，可望为肿瘤治疗开辟一条新途径。

Lymphocyte proliferation and IL-2 production could be enhanced significantly after in vivo implantation of T6.6 . These results demonstrate that fibroblasts - mediated IL-6 gene therapy could augment immune function efficiently and outline a novel strategy for cancer treatment .

美国的Sangamo生物科学公司正在开发一种模仿骨髓移植效应的基因疗法，从而“击败”艾滋病病毒感染者体内的病毒。

US company Sangamo Biosciences is developing a gene therapy to emulate the effect of a bone marrow transplant that " vanquished " the virus in an HIV patient .